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Alzheimer's disease (AD) is a neurodegenerative disorder affecting millions worldwide, necessitating early and accurate diagnosis for optimal patient management. In recent years, advancements in deep learning have shown remarkable potential…
Introduction: Machine learning (ML) has been extremely successful in identifying key features from high-dimensional datasets and executing complicated tasks with human expert levels of accuracy or greater. Methods: We summarize and…
There is a pressing need to automatically understand the state and progression of chronic neurological diseases such as dementia. The emergence of state-of-the-art sensing platforms offers unprecedented opportunities for indirect and…
Alzheimer's Disease (AD) causes a continuous decline in memory, thinking, and judgment. Traditional diagnoses are usually based on clinical experience, which is limited by some realistic factors. In this paper, we focus on exploiting deep…
Effective and accurate diagnosis of Alzheimer's disease (AD) or mild cognitive impairment (MCI) can be critical for early treatment and thus has attracted more and more attention nowadays. Since first introduced, machine learning methods…
More than 10.7% of people aged 65 and older are affected by Alzheimer's disease. Early diagnosis and treatment are crucial as most Alzheimer's patients are unaware of having it until the effects become detrimental. AI has been known to use…
Early diagnosis of Alzheimer Diagnostics (AD) is a challenging task due to its subtle and complex clinical symptoms. Deep learning-assisted medical diagnosis using image recognition techniques has become an important research topic in this…
The evolution of deep learning and artificial intelligence has significantly reshaped technological landscapes. However, their effective application in crucial sectors such as medicine demands more than just superior performance, but…
This paper presents a tutorial of an explainable approach using Convolutional Neural Network (CNN) and Gradient-weighted Class Activation Mapping (Grad-CAM) to classify four progressive dementia stages based on open MRI brain images. The…
Structural magnetic resonance imaging (sMRI) can identify subtle brain changes due to its high contrast for soft tissues and high spatial resolution. It has been widely used in diagnosing neurological brain diseases, such as Alzheimer…
Computer-aided early diagnosis of Alzheimer's disease (AD) and its prodromal form mild cognitive impairment (MCI) based on structure Magnetic Resonance Imaging (sMRI) has provided a cost-effective and objective way for early prevention and…
Pattern recognition methods using neuroimaging data for the diagnosis of Alzheimer's disease have been the subject of extensive research in recent years. In this paper, we use deep learning methods, and in particular sparse autoencoders and…
Alzheimer's Disease (AD) is the world leading cause of dementia, a progressively impairing condition leading to high hospitalization rates and mortality. To optimize the diagnostic process, numerous efforts have been directed towards the…
Alzheimer's Disease (AD) detection employs machine learning classification models to distinguish between individuals with AD and those without. Different from conventional classification tasks, we identify within-class variation as a…
This work validates the generalizability of MRI-based classification of Alzheimer's disease (AD) patients and controls (CN) to an external data set and to the task of prediction of conversion to AD in individuals with mild cognitive…
The cerebrospinal fluid (CSF) of 19 subjects who received a clinical diagnosis of Alzheimer's disease (AD) as well as of 5 pathological controls have been collected and analysed by Raman spectroscopy (RS). We investigated whether the raw…
Alzheimer's disease and Frontotemporal dementia are two major types of dementia. Their accurate diagnosis and differentiation is crucial for determining specific intervention and treatment. However, differential diagnosis of these two types…
Autistic Spectrum Disorder (ASD) is a neurological disease characterized by difficulties with social interaction, communication, and repetitive activities. While its primary origin lies in genetics, early detection is crucial, and…
Dementia and especially Alzheimer's disease (AD) are the most common causes of cognitive decline in elderly people. A spread of the above mentioned mental health problems in aging societies is causing a significant medical and economic…
Alzheimer's disease and Frontotemporal dementia are common forms of neurodegenerative dementia. Behavioral alterations and cognitive impairments are found in the clinical courses of both diseases and their differential diagnosis is…