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Phenotype-driven gene prioritization is a critical process in the diagnosis of rare genetic disorders for identifying and ranking potential disease-causing genes based on observed physical traits or phenotypes. While traditional approaches…

Quantitative Methods · Quantitative Biology 2024-04-04 Junyoung Kim , Jingye Yang , Kai Wang , Chunhua Weng , Cong Liu

The rapid development of generative artificial intelligence (GenAI) tools such as ChatGPT has intensified interest in their role in higher education, particularly in how students perceive and use them and how these perceptions may relate to…

Computers and Society · Computer Science 2026-03-20 Seyma Yaman Kayadibi

Objective To solve major clinical natural language processing (NLP) tasks using a unified text-to-text learning architecture based on a generative large language model (LLM) via prompt tuning. Methods We formulated 7 key clinical NLP tasks…

Computation and Language · Computer Science 2023-12-12 Cheng Peng , Xi Yang , Aokun Chen , Zehao Yu , Kaleb E Smith , Anthony B Costa , Mona G Flores , Jiang Bian , Yonghui Wu

Prompt learning is an effective paradigm that bridges gaps between the pre-training tasks and the corresponding downstream applications. Approaches based on this paradigm have achieved great transcendent results in various applications.…

Information Retrieval · Computer Science 2022-09-26 Zhigang Kan , Linhui Feng , Zhangyue Yin , Linbo Qiao , Xipeng Qiu , Dongsheng Li

Synthesis of digital artifacts conditioned on user prompts has become an important paradigm facilitating an explosion of use cases with generative AI. However, such models often fail to connect the generated outputs and desired target…

Machine Learning · Computer Science 2026-04-15 Melvin Wong , Yew-Soon Ong , Abhishek Gupta , Kavitesh K. Bali , Caishun Chen

While GPT has become the de-facto method for text generation tasks, its application to pinyin input method remains unexplored. In this work, we make the first exploration to leverage Chinese GPT for pinyin input method. We find that a…

Computation and Language · Computer Science 2022-03-03 Minghuan Tan , Yong Dai , Duyu Tang , Zhangyin Feng , Guoping Huang , Jing Jiang , Jiwei Li , Shuming Shi

Access to high-quality education at scale is limited by the difficulty of providing student feedback on open-ended assignments in structured domains like computer programming, graphics, and short response questions. This problem has proven…

Machine Learning · Computer Science 2021-03-25 Ali Malik , Mike Wu , Vrinda Vasavada , Jinpeng Song , Madison Coots , John Mitchell , Noah Goodman , Chris Piech

Despite universal GenAI adoption, students cannot distinguish task performance from actual learning and lack skills to leverage AI for learning, leading to worse exam performance when AI use remains unreflective. Yet few interventions…

Human-Computer Interaction · Computer Science 2026-02-19 Ruiwei Xiao , Runlong Ye , Xinying Hou , Jessica Wen , Harsh Kumar , Michael Liut , John Stamper

Inductive qualitative methods have been a mainstay of education research for decades, yet it takes much time and effort to conduct rigorously. Recent advances in artificial intelligence, particularly with generative AI (GAI), have led to…

Computation and Language · Computer Science 2024-11-12 John Chen , Alexandros Lotsos , Lexie Zhao , Grace Wang , Uri Wilensky , Bruce Sherin , Michael Horn

Large Language Models (LLMs) have demonstrated remarkable capabilities across various tasks, with their performance heavily dependent on the quality of input prompts. While prompt engineering has proven effective, it typically relies on…

Neural and Evolutionary Computing · Computer Science 2025-04-17 Xavier Sécheresse , Jacques-Yves Guilbert--Ly , Antoine Villedieu de Torcy

This study aims to explore the best practices for utilizing GenAI as a programming tool, through a comparative analysis between GPT-4 and GLM-4. By evaluating prompting strategies at different levels of complexity, we identify that simplest…

Software Engineering · Computer Science 2024-02-21 Angus Yang , Zehan Li , Jie Li

The growing integration of AI tools in software development, particularly Large Language Models (LLMs) such as ChatGPT, has revolutionized how developers approach coding tasks. However, achieving high-quality code often requires iterative…

Software Engineering · Computer Science 2025-06-03 Sophia DiCuffa , Amanda Zambrana , Priyanshi Yadav , Sashidhar Madiraju , Khushi Suman , Eman Abdullah AlOmar

Recent advancements in Natural Language Processing (NLP) have led to the development of NLP-based recommender systems that have shown superior performance. However, current models commonly treat items as mere IDs and adopt discriminative…

Information Retrieval · Computer Science 2023-04-11 Jinming Li , Wentao Zhang , Tian Wang , Guanglei Xiong , Alan Lu , Gerard Medioni

Generative AI systems such as ChatGPT and Claude are built upon language models that are typically evaluated for accuracy on curated benchmark datasets. Such evaluation paradigms measure predictive and reasoning capabilities of language…

Human-Computer Interaction · Computer Science 2025-03-03 Shreya Rajagopal , Jae Ho Sohn , Hari Subramonyam , Shiwali Mohan

Using prompts to explore the knowledge contained within pre-trained language models for downstream tasks has now become an active topic. Current prompt tuning methods mostly convert the downstream tasks to masked language modeling problems…

Computation and Language · Computer Science 2022-10-25 Jiale Han , Shuai Zhao , Bo Cheng , Shengkun Ma , Wei Lu

This paper introduces the design and development of a framework that integrates a large language model (LLM) with a retrieval-augmented generation (RAG) approach leveraging both a knowledge graph and user interaction history. The framework…

Programming Languages · Computer Science 2026-03-27 Lalita Na Nongkhai , Jingyun Wang , Adam Wynn , Takahiko Mendori

Adopting contextually appropriate, audience-tailored linguistic styles is critical to the success of user-centric language generation systems (e.g., chatbots, computer-aided writing, dialog systems). While existing approaches demonstrate…

Computation and Language · Computer Science 2023-01-26 Samraj Moorjani , Adit Krishnan , Hari Sundaram , Ewa Maslowska , Aravind Sankar

Text-to-image generative models are a new and powerful way to generate visual artwork. However, the open-ended nature of text as interaction is double-edged; while users can input anything and have access to an infinite range of…

Human-Computer Interaction · Computer Science 2023-09-29 Vivian Liu , Lydia B. Chilton

The rapid advancement of generative models has empowered modern AI systems to comprehend and produce highly sophisticated content, even achieving human-level performance in specific domains. However, these models are fundamentally…

The GPT (Generative Pre-trained Transformer) language models are an artificial intelligence and natural language processing technology that enables automatic text generation. There is a growing interest in applying GPT language models to…

Computers and Society · Computer Science 2024-03-25 Manuel de Buenaga , Francisco Javier Bueno