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Human brain development is a complex and dynamic process that is affected by several factors such as genetics, sex hormones, and environmental changes. A number of recent studies on brain development have examined functional connectivity…

Computer Vision and Pattern Recognition · Computer Science 2020-01-29 Peyman Hosseinzadeh Kassani , Li Xiao , Gemeng Zhang , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu Ping Wang

Spontaneous brain activity, as observed in functional neuroimaging, has been shown to display reproducible structure that expresses brain architecture and carries markers of brain pathologies. An important view of modern neuroscience is…

Machine Learning · Statistics 2010-11-15 Gaël Varoquaux , Alexandre Gramfort , Jean Baptiste Poline , Bertrand Thirion

Mathematical models are fundamental building blocks in the design of dynamical control systems. As control systems are becoming increasingly complex and networked, approaches for obtaining such models based on first principles reach their…

Machine Learning · Computer Science 2022-07-19 Dominik Baumann , Friedrich Solowjow , Karl H. Johansson , Sebastian Trimpe

In this study, we propose a neural network approach to capture the functional connectivities among anatomic brain regions. The suggested approach estimates a set of brain networks, each of which represents the connectivity patterns of a…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Baran Baris Kivilcim , Itir Onal Ertugrul , Fatos T. Yarman Vural

Dynamic effective connectivity networks (dECNs) reveal the changing directed brain activity and the dynamic causal influences among brain regions, which facilitate the identification of individual differences and enhance the understanding…

Machine Learning · Computer Science 2025-02-03 Faming Xu , Yiding Wang , Chen Qiao , Gang Qu , Vince D. Calhoun , Julia M. Stephen , Tony W. Wilson , Yu-Ping Wang

Effective connectivity analysis in functional magnetic resonance imaging (fMRI) studies directional interactions among brain regions and experimental stimuli. Dynamic causal modeling (DCM) is a widely used method to estimate effective…

Methodology · Statistics 2026-05-15 Kaitlyn R. Fales , Hyebin Song , Nicole A. Lazar

Causal discovery is at the core of human cognition. It enables us to reason about the environment and make counterfactual predictions about unseen scenarios that can vastly differ from our previous experiences. We consider the task of…

Machine Learning · Computer Science 2020-12-01 Yunzhu Li , Antonio Torralba , Animashree Anandkumar , Dieter Fox , Animesh Garg

Multimodal MRI offers complementary multi-scale information to characterize the brain structure. However, it remains challenging to effectively integrate multimodal MRI while achieving neuroscience interpretability. Here we propose to use…

Neurons and Cognition · Quantitative Biology 2025-12-15 Chengzhi Xia , Jianwei Chen , Yixuan Jiang , Qi Yan , Chao Li

Network control theory has recently emerged as a promising approach for understanding brain function and dynamics. By operationalizing notions of control theory for brain networks, it offers a fundamental explanation for how brain dynamics…

Quantitative Methods · Quantitative Biology 2020-03-20 Shikuang Deng , Shi Gu

The network architecture of the human brain has become a feature of increasing interest to the neuroscientific community, largely because of its potential to illuminate human cognition, its variation over development and aging, and its…

Neurons and Cognition · Quantitative Biology 2016-11-07 Richard F. Betzel , Danielle S. Bassett

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

Machine Learning · Computer Science 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

Communication within or between complex systems is commonplace in the natural sciences and fields such as graph neural networks. The brain is a perfect example of such a complex system, where communication between brain regions is…

Neurons and Cognition · Quantitative Biology 2022-10-10 Eloy Geenjaar , Noah Lewis , Amrit Kashyap , Robyn Miller , Vince Calhoun

Brain function emerges from coordinated activity across anatomically connected regions, where structural connectivity (SC) -- the network of white matter pathways - provides the physical substrate for functional connectivity (FC) -- the…

Neurons and Cognition · Quantitative Biology 2025-07-09 Sam Frank Kelemen , Joaquín Gõni , Sérgio Pequito , Arian Ashourvan

As neuroscientists we want to understand how causal interactions or mechanisms within the brain give rise to perception, cognition, and behavior. It is typical to estimate interaction effects from measured activity using statistical…

Neurons and Cognition · Quantitative Biology 2020-10-26 David Marc Anton Mehler , Konrad Paul Kording

The dynamic characteristics of multiphase industrial processes present significant challenges in the field of industrial big data modeling. Traditional soft sensing models frequently neglect the process dynamics and have difficulty in…

Machine Learning · Computer Science 2024-07-09 Yimeng He , Le Yao , Xinmin Zhang , Xiangyin Kong , Zhihuan Song

This paper describes an approach of using dynamic Structural Equation Modeling (SEM) analysis to estimate the connectivity networks from resting-state fMRI data measured by a multiband EPI sequence. Two structural equation models were…

Neurons and Cognition · Quantitative Biology 2017-04-03 Jiancheng Zhuang

Functional brain network has been widely studied to understand the relationship between brain organization and behavior. In this paper, we aim to explore the functional connectivity of brain network under a \emph{multi-step} cognitive task…

Neurons and Cognition · Quantitative Biology 2017-12-06 Shi-Min Cai , Wei Chen , Dong-Bai Liu , Ming Tang , Xun Chen

We introduce structural causal bottleneck models (SCBMs), a novel class of structural causal models. At the core of SCBMs lies the assumption that causal effects between high-dimensional variables only depend on low-dimensional summary…

Machine Learning · Statistics 2026-03-17 Simon Bing , Jonas Wahl , Jakob Runge

Naturalistic fMRI characterizes the brain as a dynamic predictive engine driven by continuous sensory streams. However, modeling the causal forward evolution in realistic neural simulation is impeded by the timescale mismatch between…

Neurons and Cognition · Quantitative Biology 2026-02-05 Xuanhua Yin , Runkai Zhao , Lina Yao , Weidong Cai

Network controllability is a powerful tool to study causal relationships in complex systems and identify the driver nodes for steering the network dynamics into desired states. However, due to ill-posed conditions, results become unreliable…

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