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We currently observe a disconcerting phenomenon in machine learning studies in psychiatry: While we would expect larger samples to yield better results due to the availability of more data, larger machine learning studies consistently show…

Alzheimer's disease (AD) is the most common form of dementia, which causes problems with memory, thinking and behavior. Growing evidence has shown that the brain connectivity network experiences alterations for such a complex disease.…

Methodology · Statistics 2020-05-29 Chen Hao , Guo Ying , He Yong , Ji Jiadong , Liu Lei , Shi Yufeng , Wang Yikai , Yu Long , Zhang Xinsheng

Objective: Tinnitus affects 10-15% of the population yet lacks objective diagnostic biomarkers. This study applied machine learning to EEG and fMRI data to identify neural signatures distinguishing tinnitus patients from healthy controls.…

Signal Processing · Electrical Eng. & Systems 2025-10-28 Kiana Kiashemshaki , Sina Samieirad , Sarvenaz Erfani , Aryan Jalaeianbanayan , Nasibeh Asadi Isakan , Hossein Najafzadeh

The detection of emotions using an Electroencephalogram (EEG) is a crucial area in brain-computer interfaces and has valuable applications in fields such as rehabilitation and medicine. In this study, we employed transfer learning to…

Signal Processing · Electrical Eng. & Systems 2024-04-09 Sidharth Sidharth , Ashish Abraham Samuel , Ranjana H , Jerrin Thomas Panachakel , Sana Parveen K

Objective: To improve prediction of Chronic Kidney Disease (CKD) progression to End Stage Renal Disease (ESRD) using machine learning (ML) and deep learning (DL) models applied to an integrated clinical and claims dataset of varying…

Quantitative Methods · Quantitative Biology 2025-05-06 Yubo Li , Rema Padman

EEG-based emotion recognition holds significant potential in the field of brain-computer interfaces. A key challenge lies in extracting discriminative spatiotemporal features from electroencephalogram (EEG) signals. Existing studies often…

Human-Computer Interaction · Computer Science 2025-12-02 Xin Zhou , Dawei Huang , Xiaojing Peng , Lijun Yin

Early diagnosis of dementia, particularly in the prodromal stage (i.e., mild cognitive impairment, or MCI), has become a research and clinical priority but remains challenging. Automated analysis of the drawing process has been studied as a…

Signal Processing · Electrical Eng. & Systems 2022-11-17 Yasunori Yamada , Masatomo Kobayashi , Kaoru Shinkawa , Miyuki Nemoto , Miho Ota , Kiyotaka Nemoto , Tetsuaki Arai

The literature manifests that schizophrenia is associated with alterations in brain network connectivity. We investigate whether large-scale Extended Granger Causality (lsXGC) can capture such alterations using resting-state fMRI data. Our…

Neurons and Cognition · Quantitative Biology 2021-01-27 Axel Wismüller , M. Ali Vosoughi

Background and Objective: It is commonly accepted that accurate monitoring of neurodegenerative diseases is crucial for effective disease management and delivery of medication and treatment. This research develops automatic clinical…

Neural and Evolutionary Computing · Computer Science 2022-05-31 Amir Dehsarvi , Jennifer Kay South Palomares , Stephen Leslie Smith

Resting-state functional Magnetic Resonance Imaging (R-fMRI) holds the promise to reveal functional biomarkers of neuropsychiatric disorders. However, extracting such biomarkers is challenging for complex multi-faceted neuropatholo-gies,…

Emotions are integral to human social interactions, with diverse responses elicited by various situational contexts. Particularly, the prevalence of negative emotional states has been correlated with negative outcomes for mental health,…

Computation and Language · Computer Science 2024-01-10 Abu Bakar Siddiqur Rahman , Hoang-Thang Ta , Lotfollah Najjar , Azad Azadmanesh , Ali Saffet Gönül

Major depressive disorder (MDD) is a common mental disorder that typically affects a person's mood, cognition, behavior, and physical health. Resting-state functional magnetic resonance imaging (rs-fMRI) data are widely used for…

Image and Video Processing · Electrical Eng. & Systems 2024-06-10 Yunling Ma , Chaojun Zhang , Xiaochuan Wang , Qianqian Wang , Liang Cao , Limei Zhang , Mingxia Liu

Cardiovascular diseases (CVD) are a predominant health concern globally, emphasizing the need for advanced diagnostic techniques. In our research, we present an avant-garde methodology that synergistically integrates ECG readings and…

Cardiovascular disease (CVD) is a major pediatric health burden, and early screening is of critical importance. Electrocardiography (ECG), as a noninvasive and accessible tool, is well suited for this purpose. This paper presents the first…

Signal Processing · Electrical Eng. & Systems 2025-10-07 Yiqiao Chen

Neuroscientific studies aim to find an accurate and reliable brain Effective Connectome (EC). Although current EC discovery methods have contributed to our understanding of brain organization, their performances are severely constrained by…

Machine Learning · Computer Science 2024-03-12 Abdolmahdi Bagheri , Mahdi Dehshiri , Yamin Bagheri , Alireza Akhondi-Asl , Babak Nadjar Araabi

Major depressive disorder (MDD) is a prevalent psychiatric disorder that is associated with significant healthcare burden worldwide. Phenotyping of MDD can help early diagnosis and consequently may have significant advantages in patient…

Recently there has been significant interest in measuring time-varying functional connectivity (TVC) between different brain regions using resting-state functional magnetic resonance imaging (rs-fMRI) data. One way to assess the…

Signal Processing · Electrical Eng. & Systems 2022-03-29 Hamed Honari , Martin A. Lindquist

This study investigates the potential of deep learning methods to identify individuals with suspected COVID-19 infection using remotely collected heart-rate data. The study utilises data from the ongoing EU IMI RADAR-CNS research project…

Despite progress in deep learning for Alzheimer's disease (AD) diagnostics, models trained on structural magnetic resonance imaging (sMRI) often do not perform well when applied to new cohorts due to domain shifts from varying scanners,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Zobia Batool , Diala Lteif , Vijaya B. Kolachalama , Huseyin Ozkan , Erchan Aptoula

The goal of the present study is to identify autism using machine learning techniques and resting-state brain imaging data, leveraging the temporal variability of the functional connections (FC) as the only information. We estimated and…

Neurons and Cognition · Quantitative Biology 2017-12-22 Ravi Tejwani , Adam Liska , Hongyuan You , Jenna Reinen , Payel Das