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Related papers: Re-evaluating Retrosynthesis Algorithms with Synth…

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Retrosynthesis analysis is pivotal yet challenging in drug discovery and organic chemistry. Despite the proliferation of computational tools over the past decade, AI-based systems often fall short in generalizing across diverse reaction…

Machine Learning · Computer Science 2024-08-21 Yifei Yang , Runhan Shi , Zuchao Li , Shu Jiang , Bao-Liang Lu , Yang Yang , Hai Zhao

Autonomous agents are increasingly expected to support scientific research, and recent benchmarks report progress in code repair and autonomous experimentation. However, these evaluations typically assume a pre-configured execution…

Software Engineering · Computer Science 2026-03-12 Yubang Wang , Chenxi Zhang , Bowen Chen , Zezheng Huai , Zihao Dai , Xinchi Chen , Yuxin Wang , Yining Zheng , Jingjing Gong , Xipeng Qiu

Program synthesis is a class of regression problems where one seeks a solution, in the form of a source-code program, mapping the inputs to their corresponding outputs exactly. Due to its precise and combinatorial nature, program synthesis…

Artificial Intelligence · Computer Science 2018-06-08 Yewen Pu , Zachery Miranda , Armando Solar-Lezama , Leslie Pack Kaelbling

Program synthesis and repair have emerged as an exciting area of research, driven by the potential for revolutionary advances in programmer productivity. Among most promising ideas emerging for synthesis are syntax-driven search,…

Programming Languages · Computer Science 2017-07-14 Manos Koukoutos , Mukund Raghothaman , Etienne Kneuss , Viktor Kuncak

The increasing attention on deep learning has tremendously spurred the design of intelligence processing hardware. The variety of emerging intelligence processors requires standard benchmarks for fair comparison and system optimization (in…

Designing synthetically accessible molecules and recommending analogs to unsynthesizable molecules are important problems for accelerating molecular discovery. We reconceptualize both problems using ideas from program synthesis. Drawing…

Biomolecules · Quantitative Biology 2025-03-04 Michael Sun , Alston Lo , Minghao Guo , Jie Chen , Connor Coley , Wojciech Matusik

Time-series forecasting is an essential task with wide real-world applications across domains. While recent advances in deep learning have enabled time-series forecasting models with accurate predictions, there remains considerable debate…

Machine Learning · Computer Science 2026-03-26 Zhiyuan Zhao , Juntong Ni , Shangqing Xu , Haoxin Liu , Wei Jin , B. Aditya Prakash

The community of program optimisation and analysis, code performance evaluation, parallelisation and optimising compilation has published since many decades hundreds of research and engineering articles in major conferences and journals.…

Performance · Computer Science 2009-07-06 Sid Touati

The evaluation of clustering algorithms can involve running them on a variety of benchmark problems, and comparing their outputs to the reference, ground-truth groupings provided by experts. Unfortunately, many research papers and graduate…

Machine Learning · Computer Science 2023-10-27 Marek Gagolewski

Molecule synthesis through machine learning is one of the fundamental problems in drug discovery. Current data-driven strategies employ one-step retrosynthesis models and search algorithms to predict synthetic routes in a top-bottom manner.…

Machine Learning · Computer Science 2024-06-05 Songtao Liu , Hanjun Dai , Yue Zhao , Peng Liu

The aim of this work is to address issues where formal specifications cannot be realized on a given dynamical system subjected to a changing environment. Such failures occur whenever the dynamics of the system restrict the robot in such a…

Synthesizing relational data has started to receive more attention from researchers, practitioners, and industry. The task is more difficult than synthesizing a single table due to the added complexity of relationships between tables. For…

Databases · Computer Science 2024-10-07 Valter Hudovernik , Martin Jurkovič , Erik Štrumbelj

Computer-assisted synthesis planning aims to help chemists find better reaction pathways faster. Finding viable and short pathways from sugar molecules to value-added chemicals can be modeled as a retrosynthesis planning problem with a…

Other Computer Science · Computer Science 2019-11-19 Peihong Jiang , Hieu Doan , Sandeep Madireddy , Rajeev Surendran Assary , Prasanna Balaprakash

Existing approaches typically rely on large-scale fine-tuning to adapt LLMs for information reranking tasks, which is computationally expensive. In this work, we demonstrate that modern LLMs can be effectively adapted using only minimal,…

Computation and Language · Computer Science 2025-10-28 Tingyu Song , Yilun Zhao , Siyue Zhang , Chen Zhao , Arman Cohan

We report on the design and results of the second reactive synthesis competition (SYNTCOMP 2015). We describe our extended benchmark library, with 6 completely new sets of benchmarks, and additional challenging instances for 4 of the…

Evaluating performance across optimization algorithms on many problems presents a complex challenge due to the diversity of numerical scales involved. Traditional data processing methods, such as hypothesis testing and Bayesian inference,…

Optimization and Control · Mathematics 2024-09-10 Yunpeng Jinng , Qunfeng Liu

Training certifiably robust neural networks is an important but challenging task. While many algorithms for (deterministic) certified training have been proposed, they are often evaluated on different training schedules, certification…

Machine Learning · Computer Science 2025-05-29 Yuhao Mao , Stefan Balauca , Martin Vechev

We present a new framework and associated synthesis algorithms for program synthesis over noisy data, i.e., data that may contain incorrect/corrupted input-output examples. This framework is based on an extension of finite tree automata…

Programming Languages · Computer Science 2021-03-15 Shivam Handa , Martin Rinard

Classical and natural language planning tasks remain a difficult domain for modern large language models (LLMs). In this work, we lay the foundations for improving planning capabilities of LLMs. First, we construct a comprehensive benchmark…

Computation and Language · Computer Science 2024-11-05 Bernd Bohnet , Azade Nova , Aaron T Parisi , Kevin Swersky , Katayoon Goshvadi , Hanjun Dai , Dale Schuurmans , Noah Fiedel , Hanie Sedghi

Nowadays, software artifacts are ubiquitous in our lives being an essential part of home appliances, cars, cell phones, and even in more critical activities like aeronautics and health sciences. In this context software failures may produce…

Software Engineering · Computer Science 2014-01-07 Manuel Giménez , Mariano M. Moscato , Carlos G. Lopez Pombo , Marcelo F. Frias