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Artificial intelligence (AI) is transforming scientific research, with explainable AI methods like concept-based models (CMs) showing promise for new discoveries. However, in molecular science, CMs are less common than black-box models like…

Artificial Intelligence · Computer Science 2024-12-17 Zimin Zhang , Qianli Wu , Botao Xia , Fang Sun , Ziniu Hu , Yizhou Sun , Shichang Zhang

Concept Bottleneck Models (CBMs) have emerged as a cornerstone approach for interpretable machine learning, providing human-understandable intermediate representations through explicit concept activations. However, this interpretability…

Machine Learning · Computer Science 2026-05-26 Aditya Sridhar

Deep neural networks based on layer-stacking architectures have historically suffered from poor inherent interpretability. Meanwhile, symbolic probabilistic models function with clear interpretability, but how to combine them with neural…

Computation and Language · Computer Science 2023-03-07 Xiang Hu , Xinyu Kong , Kewei Tu

Machine learning (ML) has seen significant growth in both popularity and importance. The high prediction accuracy of ML models is often achieved through complex black-box architectures that are difficult to interpret. This interpretability…

Machine Learning · Statistics 2024-07-29 David Köhler , David Rügamer , Matthias Schmid

In recent years, the black-box nature of deep learning models has limited their application in high-stakes domains such as medical diagnosis and finance, where interpretability is essential. To address this, we propose a novel approach…

Computation and Language · Computer Science 2026-05-26 Yike Sun , Mingkun Xu , Mu You , Zhongzhi He , Henghua Shen , Zehan Tan , Derek F. Wong , Tao Fang

Tabular data is often hidden in text, particularly in medical diagnostic reports. Traditional machine learning (ML) models designed to work with tabular data, cannot effectively process information in such form. On the other hand, large…

Machine Learning · Computer Science 2023-06-09 Aleksa Bisercic , Mladen Nikolic , Mihaela van der Schaar , Boris Delibasic , Pietro Lio , Andrija Petrovic

In machine learning algorithm design, there exists a trade-off between the interpretability and performance of the algorithm. In general, algorithms which are simpler and easier for humans to comprehend tend to show worse performance than…

Machine Learning · Computer Science 2024-07-15 Eric M. Vernon , Naoki Masuyama , Yusuke Nojima

Many interpretable AI approaches have been proposed to provide plausible explanations for a model's decision-making. However, configuring an explainable model that effectively communicates among computational modules has received less…

Machine Learning · Computer Science 2023-11-09 Jinyung Hong , Keun Hee Park , Theodore P. Pavlic

Despite the high performance of neural network-based time series forecasting methods, the inherent challenge in explaining their predictions has limited their applicability in certain application areas. Due to the difficulty in identifying…

Machine Learning · Computer Science 2023-01-09 Ozan Ozyegen , Juyoung Wang , Mucahit Cevik

Concept Bottleneck Models (CBMs) aim to enhance interpretability by predicting human-understandable concepts as intermediates for decision-making. However, these models often face challenges in ensuring reliable concept representations,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-04 Yuxuan Cai , Xiyu Wang , Satoshi Tsutsui , Winnie Pang , Bihan Wen

Time series classification is a task of paramount importance, as this kind of data often arises in safety-critical applications. However, it is typically tackled with black-box deep learning methods, making it hard for humans to understand…

Machine Learning · Computer Science 2025-08-28 Irene Ferfoglia , Simone Silvetti , Gaia Saveri , Laura Nenzi , Luca Bortolussi

Multi-modal Large Language Models (MLLMs) have demonstrated remarkable capabilities in understanding and generating content across various modalities, such as images and text. However, their interpretability remains a challenge, hindering…

Computer Vision and Pattern Recognition · Computer Science 2024-05-29 Loris Giulivi , Giacomo Boracchi

Models based on human-understandable concepts have received extensive attention to improve model interpretability for trustworthy artificial intelligence in the field of medical image analysis. These methods can provide convincing…

Computer Vision and Pattern Recognition · Computer Science 2024-12-25 Hongmei Wang , Junlin Hou , Hao Chen

Concept Bottleneck Models (CBMs) have emerged as a promising interpretable method whose final prediction is based on intermediate, human-understandable concepts rather than the raw input. Through time-consuming manual interventions, a user…

Machine Learning · Computer Science 2024-10-18 Moritz Vandenhirtz , Sonia Laguna , Ričards Marcinkevičs , Julia E. Vogt

Interpretability benefits the theoretical understanding of representations. Existing word embeddings are generally dense representations. Hence, the meaning of latent dimensions is difficult to interpret. This makes word embeddings like a…

Computation and Language · Computer Science 2023-06-27 Minxue Xia , Hao Zhu

Interpretable text representations should expose coordinates that are not only predictive, but also meaningful enough for independent auditors to apply. Existing discriminative representations often use anonymous embedding directions, while…

Computation and Language · Computer Science 2026-05-21 Tong Wang , Yiqing Xu , Leo Yang Yang

Concept bottleneck models (CBMs), which predict human-interpretable concepts (e.g., nucleus shapes in cell images) before predicting the final output (e.g., cell type), provide insights into the decision-making processes of the model.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Winnie Pang , Xueyi Ke , Satoshi Tsutsui , Bihan Wen

Concept bottleneck models (CBMs) ensure interpretability by decomposing predictions into human interpretable concepts. Yet the annotations used for training CBMs that enable this transparency are often noisy, and the impact of such…

Machine Learning · Computer Science 2026-02-02 Seonghwan Park , Jueun Mun , Donghyun Oh , Namhoon Lee

InterpretML is an open-source Python package which exposes machine learning interpretability algorithms to practitioners and researchers. InterpretML exposes two types of interpretability - glassbox models, which are machine learning models…

Machine Learning · Computer Science 2019-09-23 Harsha Nori , Samuel Jenkins , Paul Koch , Rich Caruana

The field of machine learning has seen tremendous progress in recent years, with deep learning models delivering exceptional performance across a range of tasks. However, these models often come at the cost of interpretability, as they…

Machine Learning · Computer Science 2024-01-08 Shun Liu