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Multiple instance learning (MIL) has emerged as a popular method for classifying histopathology whole slide images (WSIs). Existing approaches typically rely on frozen pre-trained models to extract instance features, neglecting the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Yi Lin , Zhengjie Zhu , Kwang-Ting Cheng , Hao Chen

This paper proposes a novel method of classifying malware into families using high-resolution greyscale images and multiple instance learning to overcome adversarial binary enlargement. Current methods of visualisation-based malware…

Cryptography and Security · Computer Science 2023-11-22 Tim Peters , Hikmat Farhat

Various multi-instance learning (MIL) based approaches have been developed and successfully applied to whole-slide pathological images (WSI). Existing MIL methods emphasize the importance of feature aggregators, but largely neglect the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Yicheng Song , Tiancheng Lin , Die Peng , Su Yang , Yi Xu

Although multiple instance learning (MIL) methods are widely used for automatic tumor detection on whole slide images (WSI), they suffer from the extreme class imbalance within the small tumor WSIs. This occurs when the tumor comprises only…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Ziyu Su , Mostafa Rezapour , Usama Sajjad , Shuo Niu , Metin Nafi Gurcan , Muhammad Khalid Khan Niazi

Multiple instance learning (MIL) has emerged as the dominant paradigm for whole slide image (WSI) analysis in computational pathology, achieving strong diagnostic performance through patch-level feature aggregation. However, existing MIL…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Yiran Song , Yikai Zhang , Shuang Zhou , Guojun Xiong , Xiaofeng Yang , Nian Wang , Fenglong Ma , Rui Zhang , Mingquan Lin

Convolutional neural networks can be trained to perform histology slide classification using weak annotations with multiple instance learning (MIL). However, given the paucity of labeled histology data, direct application of MIL can easily…

Computer Vision and Pattern Recognition · Computer Science 2019-11-05 Ming Y. Lu , Richard J. Chen , Jingwen Wang , Debora Dillon , Faisal Mahmood

Multi-Instance Learning (MIL) is pivotal for analyzing complex, weakly labeled datasets, such as whole-slide images (WSIs) in computational pathology, where bags comprise unordered collections of instances with sparse diagnostic relevance.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Yuedi Zhang , Zhixiang Xia , Guosheng Yin , Bin Liu

Prostate cancer is the second deadliest cancer for American men. While Magnetic Resonance Imaging (MRI) is increasingly used to guide targeted biopsies for prostate cancer diagnosis, its utility remains limited due to high rates of false…

Multi-label image recognition aims to predict a set of labels that present in an image. The key to deal with such problem is to mine the associations between image contents and labels, and further obtain the correct assignments between…

Computer Vision and Pattern Recognition · Computer Science 2023-04-25 Yanan Wu , Songhe Feng , Yang Wang

Multiple instance learning (MIL) is the standard approach for whole-slide image (WSI) classification and survival prediction, where attention-based models ag gregate patch features into slide-level predictions. These models treat attention…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Xiangyu Li , Ran Su

Multiple instance learning (MIL) can reduce the need for costly annotation in tasks such as semantic segmentation by weakening the required degree of supervision. We propose a novel MIL formulation of multi-class semantic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2015-04-16 Deepak Pathak , Evan Shelhamer , Jonathan Long , Trevor Darrell

Multiple Instance Learning (MIL) has been widely used in weakly supervised whole slide image (WSI) classification. Typical MIL methods include a feature embedding part, which embeds the instances into features via a pre-trained feature…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Peijie Qiu , Pan Xiao , Wenhui Zhu , Yalin Wang , Aristeidis Sotiras

Multiple Instance Learning (MIL) involves predicting a single label for a bag of instances, given positive or negative labels at bag-level, without accessing to label for each instance in the training phase. Since a positive bag contains…

Machine Learning · Computer Science 2020-09-09 Beomjo Shin , Junsu Cho , Hwanjo Yu , Seungjin Choi

Multiple Instance Learning (MIL) has been widely applied in histopathology to classify Whole Slide Images (WSIs) with slide-level diagnoses. While the ground truth is established by expert pathologists, the slides can be difficult to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Marie Arrivat , Rémy Peyret , Elsa Angelini , Pietro Gori

Foundation models (FMs) have transformed computational pathology by providing powerful, general-purpose feature extractors. However, adapting and benchmarking individual FMs for specific diagnostic tasks is often time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Peiran Quan , Zifan Gu , Zhuo Zhao , Qin Zhou , Donghan M. Yang , Ruichen Rong , Yang Xie , Guanghua Xiao

The application of AI in oncology has been limited by its reliance on large, annotated datasets and the need for retraining models for domain-specific diagnostic tasks. Taking heed of these limitations, we investigated in-context learning…

Image and Video Processing · Electrical Eng. & Systems 2025-05-15 Mobina Shrestha , Bishwas Mandal , Vishal Mandal , Asis Shrestha

Supervised learning tasks such as cancer survival prediction from gigapixel whole slide images (WSIs) are a critical challenge in computational pathology that requires modeling complex features of the tumor microenvironment. These learning…

Image and Video Processing · Electrical Eng. & Systems 2022-11-22 Iain Carmichael , Andrew H. Song , Richard J. Chen , Drew F. K. Williamson , Tiffany Y. Chen , Faisal Mahmood

Detecting anomalies over real-world datasets remains a challenging task. Data annotation is an intensive human labor problem, particularly in sequential datasets, where the start and end time of anomalies are not known. As a result, data…

Machine Learning · Computer Science 2022-10-05 Parastoo Kamranfar , David Lattanzi , Amarda Shehu , Daniel Barbará

In this paper, we address the challenge of few-shot classification in histopathology whole slide images (WSIs) by utilizing foundational vision-language models (VLMs) and slide-level prompt learning. Given the gigapixel scale of WSIs,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Devavrat Tomar , Guillaume Vray , Dwarikanath Mahapatra , Sudipta Roy , Jean-Philippe Thiran , Behzad Bozorgtabar

Multi-instance multi-label (MIML) learning is a challenging problem in many aspects. Such learning approaches might be useful for many medical diagnosis applications including breast cancer detection and classification. In this study subset…

Computer Vision and Pattern Recognition · Computer Science 2015-10-13 Baris Gecer , Ozge Yalcinkaya , Onur Tasar , Selim Aksoy
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