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In an order-of-addition experiment, each treatment is a permutation of m components. It is often unaffordable to test all the m! treatments, and the design problem arises. We consider a model that incorporates the order of each pair of…

Statistics Theory · Mathematics 2018-05-15 Jiayu Peng , Rahul Mukerjee , Dennis K. J. Lin

In this paper, we propose iterative inner/outer approximations based on a recent notion of block factor-width-two matrices for solving semidefinite programs (SDPs). Our inner/outer approximating algorithms generate a sequence of upper/lower…

Optimization and Control · Mathematics 2022-09-30 Feng-Yi Liao , Yang Zheng

This work explores the nature of augmented importance sampling in safety-constrained model predictive control problems. When operating in a constrained environment, sampling based model predictive control and motion planning typically…

Systems and Control · Electrical Eng. & Systems 2022-04-13 Manan Gandhi , Hassan Almubarak , Yuichiro Aoyama , Evangelos Theodorou

Dynamic multi-objective optimization problems (DMOPs) are widely accepted to be more challenging than stationary problems due to the time-dependent nature of the objective functions and/or constraints. Evaluation of purpose-built algorithms…

Neural and Evolutionary Computing · Computer Science 2022-04-11 Daniel Herring , Michael Kirley , Xin Yao

Block coordinate descent (BCD) methods are prevalent in large scale optimization problems due to the low memory and computational costs per iteration, the predisposition to parallelization, and the ability to exploit the structure of the…

Optimization and Control · Mathematics 2025-10-31 Luis Briceño-Arias , Paulo Gonçalves , Guillaume Lauga , Nelly Pustelnik , Elisa Riccietti

Biomarker-guided designs are increasingly used to evaluate personalized treatments based on patients' biomarker status in Phase II and III clinical trials. With adaptive enrichment, these designs can improve the efficiency of evaluating the…

Methodology · Statistics 2024-06-11 Kaiyuan Hua , Hwanhee Hong , Xiaofei Wang

Given the stringent requirements of energy efficiency for Internet-of-Things edge devices, approximate multipliers, as a basic component of many processors and accelerators, have been constantly proposed and studied for decades, especially…

Hardware Architecture · Computer Science 2023-06-30 Ying Wu , Chuangtao Chen , Weihua Xiao , Xuan Wang , Chenyi Wen , Jie Han , Xunzhao Yin , Weikang Qian , Cheng Zhuo

Achieving fault-tolerance will require a strong relationship between the hardware and the protocols used. Different approaches will therefore naturally have tailored proof-of-principle experiments to benchmark progress. Nevertheless,…

Quantum Physics · Physics 2024-05-28 Milan Liepelt , Tommaso Peduzzi , James R. Wootton

We present a novel approach for constructing discrete optimization benchmarks that enables fine-grained control over problem properties, and such benchmarks can facilitate analyzing discrete algorithm behaviors. We build benchmark problems…

Neural and Evolutionary Computing · Computer Science 2026-04-09 Furong Ye , Frank Neumann , Thomas Bäck , Niki van Stein

We consider the problem of constructing optimal designs for model discrimination between competing regression models. Various new properties of optimal designs with respect to the popular $T$-optimality criterion are derived, which in many…

Statistics Theory · Mathematics 2009-08-14 Holger Dette , Stefanie Titoff

A/B experiments are commonly used in research to compare the effects of changing one or more variables in two different experimental groups - a control group and a treatment group. While the benefits of using A/B experiments are widely…

Software Engineering · Computer Science 2023-09-26 Andrew Hornback , Sungeun An , Scott Bunin , Stephen Buckley , John Kos , Ashok Goel

Background: Ventilator-associated pneumonia (VAP) in traumatic brain injury (TBI) patients poses a significant mortality risk and imposes a considerable financial burden on patients and healthcare systems. Timely detection and…

Machine Learning · Computer Science 2024-08-05 Negin Ashrafi , Armin Abdollahi , Maryam Pishgar

This paper investigates the problem of efficient constrained global optimization of hybrid models that are a composition of a known white-box function and an expensive multi-output black-box function subject to noisy observations, which…

Machine Learning · Statistics 2023-07-31 Congwen Lu , Joel A. Paulson

Data-driven modeling plays an increasingly important role in different areas of engineering. For most of existing methods, such as genetic programming (GP), the convergence speed might be too slow for large scale problems with a large…

Optimization and Control · Mathematics 2017-06-29 Chen Chen , Changtong Luo , Zonglin Jiang

In nonadaptive group testing, the main research objective is to design an efficient algorithm to identify a set of up to $t$ positive elements among $n$ samples with as few tests as possible. Disjunct matrices and separable matrices are two…

Combinatorics · Mathematics 2021-10-15 Bingchen Qian , Xin Wang , Gennian Ge

Multimodal Large Language Models (MLLMs) are undergoing rapid progress and represent the frontier of AI development. However, their training and inference efficiency have emerged as a core bottleneck in making MLLMs more accessible and…

A Bayesian design is given by maximising an expected utility over a design space. The utility is chosen to represent the aim of the experiment and its expectation is taken with respect to all unknowns: responses, parameters and/or models.…

Methodology · Statistics 2019-01-16 Antony M. Overstall , James M. McGree

Adaptive designs are increasingly used in clinical trials and online experiments to improve participant outcomes by dynamically updating treatment allocation as data accumulate. In practice, experimenters often consider multiple candidate…

Methodology · Statistics 2026-04-08 Wenxin Zhang , Aaron Hudson , Maya Petersen , Mark van der Laan

Under a generalised estimating equation analysis approach, approximate design theory is used to determine Bayesian D-optimal designs. For two examples, considering simple exchangeable and exponential decay correlation structures, we compare…

Methodology · Statistics 2024-02-16 Laura Etfer , James M. S. Wason , Michael J. Grayling

The unextendible orthogonal matrices (UPBs) can be used for various problems in quantum information. We provide an algorithm to check if two UPBs are non-equivalent to each other. We give a method to construct UPBs and we apply this method…

Quantum Physics · Physics 2024-02-20 Caohan Cheng , Lin Chen
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