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We investigate block designs, under the A- and MV-criteria, when each treatment can have only one or two replications due to resource constraints, as can happen, for example, in early generation varietal trials. While these are commonly…

Statistics Theory · Mathematics 2026-03-25 R. A. Bailey , Rahul Mukerjee

Optimal block designs in small blocks are explored when the treatments have a natural ordering and interest lies in comparing consecutive pairs of treatments. We first develop an approximate theory which leads to a convenient multiplicative…

Statistics Theory · Mathematics 2014-05-20 S. Huda , Rahul Mukerjee

Balanced incomplete block designs (BIBDs) are a class of designs with v treatments and b blocks of size k that are optimal with regards to a wide range of optimality criteria, but it is not clear which designs to choose for combinations of…

Statistics Theory · Mathematics 2019-02-13 Sera Aylin Cakiroglu , Peter J Cameron

This paper is about the construction of augmented row-column designs for unreplicated trials. The method uses the representation of a $k \times t$ equireplicate incomplete-block design with $t$ treatments in $t$ blocks of size $k$, termed…

Methodology · Statistics 2025-02-26 R. A. Bailey , L. M. Haines

This paper deals exclusively with crossover designs for the purpose of comparing t test treatments with a control treatment when the number of periods is no larger than t+1. Among other results it specifies sufficient conditions for a…

Statistics Theory · Mathematics 2007-06-13 A. S. Hedayat , Min Yang

A/B test, a simple type of controlled experiment, refers to the statistical procedure of experimenting to compare two treatments applied to test subjects. For example, many IT companies frequently conduct A/B tests on their users who are…

Methodology · Statistics 2026-05-12 Qiong Zhang , Lulu Kang

We consider experiments for comparing treatments using units that are ordered linearly over time or space within blocks. In addition to the block effect, we assume that a trend effect influences the response. The latter is modeled as a…

Statistics Theory · Mathematics 2008-12-18 Dibyen Majumdar , John Stufken

For large classes of group testing problems, we derive lower bounds for the probability that all significant items are uniquely identified using specially constructed random designs. These bounds allow us to optimize parameters of the…

Statistics Theory · Mathematics 2022-02-17 Jack Noonan , Anatoly Zhigljavsky

We consider designs for cancer trials which allow each medical centre to treat only a limited number of cancer types with only a limited number of drugs. We specify desirable properties of these designs, and prove some consequences. Then we…

Applications · Statistics 2019-05-31 R. A. Bailey , Peter J. Cameron

For paired comparison experiments involving competing options described by two-level attributes several different methods of constructing designs having block paired observations under the main effects model are presented. These designs are…

Methodology · Statistics 2019-10-16 Eric Nyarko

Judging scholarly posters creates a challenge to assign the judges efficiently. If there are many posters and few reviews per judge, the commonly used Balanced Incomplete Block Design is not a feasible option. An additional challenge is an…

Applications · Statistics 2018-06-04 Xiaoyue Niu , James L. Rosenberger

While clinical trials are the state-of-the-art methods to assess the effect of new medication in a comparative manner, benchmarking in the field of medical image analysis is performed by so-called challenges. Recently, comprehensive…

Computer Vision and Pattern Recognition · Computer Science 2023-07-17 Annika Reinke , Georg Grab , Lena Maier-Hein

We show that in a complex d-dimensional vector space, one can find O(d) bases whose elements form a 2-design. Such vector sets generalize the notion of a maximal collection of mutually unbiased bases (MUBs). MUBs have manifold applications…

Quantum Physics · Physics 2008-05-19 Gary McConnell , David Gross

Experimental design has emerged as a powerful approach for improving the sample efficiency of A/B testing, yet existing designs rely critically on correctly specified models. We study robust sequential experimental design under model…

Machine Learning · Statistics 2026-05-14 Qianglin Wen , Xiangkun Wu , Chengchun Shi , Ting Li , Niansheng Tang , Yingying Zhang , Hongtu Zhu

Designs for Order-of-Addition (OofA) experiments have received growing attention due to their impact on responses based on the sequence of component addition. In certain cases, these experiments involve heterogeneous groups of units, which…

Methodology · Statistics 2026-02-04 Chang-Yun Lin

Resolvable designs with two blocks per replicate are studied from an optimality perspective. Because in practice the number of replicates is typically less than the number of treatments, arguments can be based on the dual of the information…

Statistics Theory · Mathematics 2009-09-29 J. P. Morgan , Brian H. Reck

A new gradient-based adaptive sampling method is proposed for design of experiments applications which balances space filling, local refinement, and error minimization objectives while reducing reliance on delicate tuning parameters. High…

Methodology · Statistics 2024-05-09 Lucas Caparini , Gwynn J. Elfring , Mauricio Ponga

Follow-up experimental designs are popularly used in industry. In many follow-up designs, some additional factors with two or three levels may be added in the follow-up stage since they are quite important but may be neglected in the first…

Statistics Theory · Mathematics 2018-08-23 Feng Yang , Yong-Dao Zhou , Aijun Zhang

This work provides performance guarantees for the greedy solution of experimental design problems. In particular, it focuses on A- and E-optimal designs, for which typical guarantees do not apply since the mean-square error and the maximum…

Machine Learning · Computer Science 2018-02-01 Luiz F. O. Chamon , Alejandro Ribeiro

It is increasingly common for therapies in oncology to be given in combination. In some cases, patients can benefit from the interaction between two drugs, although often at the risk of higher toxicity. A large number of designs to conduct…

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