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Interpretability in machine learning models is important in high-stakes decisions, such as whether to order a biopsy based on a mammographic exam. Mammography poses important challenges that are not present in other computer vision tasks:…

Machine Learning · Computer Science 2021-03-24 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

Understanding how galaxies trace the underlying matter density field is essential for characterizing the influence of the large-scale structure on galaxy formation, being therefore a key ingredient in observational cosmology. This…

Black box machine learning models are currently being used for high stakes decision-making throughout society, causing problems throughout healthcare, criminal justice, and in other domains. People have hoped that creating methods for…

Machine Learning · Statistics 2019-09-24 Cynthia Rudin

The rapid adoption of complex Artificial Intelligence (AI) and Machine Learning (ML) models has led to their characterization as black boxes due to the difficulty of explaining their internal decision-making processes. This lack of…

Machine Learning · Computer Science 2026-01-13 Silvia Ruiz-España , Laura Arnal , François Signol , Juan-Carlos Perez-Cortes , Joaquim Arlandis

Here we investigate the possibility that some globular clusters (GCs) harbor intermediate mass black holes (BH) in their centers and are also embedded in a low-mass dark matter (DM) halo. Up to date, there is no evidence on whether or not…

High Energy Astrophysical Phenomena · Physics 2020-08-19 Elaine C. F. S. Fortes , Oswaldo D. Miranda , Floyd W. Stecker , Carlos A. Wuensche

During the last decades, much effort has been devoted to explain the discrepancy between the amount of intracluster medium (ICM) estimated from stellar evolution theories and that emerging from observations in globular clusters (GCs). One…

Astrophysics of Galaxies · Physics 2016-07-27 C. Pepe , L. J. Pellizza

Most pregnancies and births result in a good outcome, but complications are not uncommon and when they do occur, they can be associated with serious implications for mothers and babies. Predictive modeling has the potential to improve…

Many observed globular clusters (GCs) seem to show a central overabundance of mass whose nature has not yet fully understood. Indeed, it is not clear whether it is due to a central intermediate mass black hole (IMBH) or to a massive stellar…

Astrophysics of Galaxies · Physics 2016-06-23 Manuel Arca-Sedda

Machine learning models have had discernible achievements in a myriad of applications. However, most of these models are black-boxes, and it is obscure how the decisions are made by them. This makes the models unreliable and untrustworthy.…

Machine Learning · Computer Science 2020-03-23 Raha Moraffah , Mansooreh Karami , Ruocheng Guo , Adrienne Raglin , Huan Liu

Most of the work on interpretable machine learning has focused on designing either inherently interpretable models, which typically trade-off accuracy for interpretability, or post-hoc explanation systems, which lack guarantees about their…

Machine Learning · Computer Science 2019-06-05 Gregory Plumb , Maruan Al-Shedivat , Eric Xing , Ameet Talwalkar

Model interpretability is an increasingly important component of practical machine learning. Some of the most common forms of interpretability systems are example-based, local, and global explanations. One of the main challenges in…

Machine Learning · Computer Science 2019-01-08 Gregory Plumb , Denali Molitor , Ameet Talwalkar

Concept-Based Models (CBMs) are a class of deep learning models that provide interpretability by explaining predictions through high-level concepts. These models first predict concepts and then use them to perform a downstream task.…

Machine Learning · Computer Science 2025-06-27 David Debot , Pietro Barbiero , Gabriele Dominici , Giuseppe Marra

Interpretability of machine learning models is critical for data-driven precision medicine efforts. However, highly predictive models are generally complex and are difficult to interpret. Here using Model-Agnostic Explanations algorithm, we…

Quantitative Methods · Quantitative Biology 2016-10-31 Gajendra Jung Katuwal , Robert Chen

Interpretable machine learning has become a strong competitor for traditional black-box models. However, the possible loss of the predictive performance for gaining interpretability is often inevitable, putting practitioners in a dilemma of…

Machine Learning · Computer Science 2019-05-13 Tong Wang , Qihang Lin

With the advancement of technology for artificial intelligence (AI) based solutions and analytics compute engines, machine learning (ML) models are getting more complex day by day. Most of these models are generally used as a black box…

Machine Learning · Computer Science 2022-10-11 P. Sai Ram Aditya , Mayukha Pal

The dynamical evolution of globular clusters (GCs) is tied to their binary population, as binaries segregate to the cluster centre, leading to an increased binary fraction in the core. This central overabundance of mainly hard binaries can…

Intermediate mass black holes (IMBHs) are an (as yet) elusive class of black holes that are expected to lie in the $10^2-10^5\,M_{\odot}$ range, between the firmly established stellar-mass black holes and ${\gtrsim}10^6\,M_{\odot}$…

Astrophysics of Galaxies · Physics 2018-05-16 Filippos Koliopanos

Intermediate mass black holes (IMBHs) have masses between the $10^2\!-\!10^6$ M$_\odot$ and are key to our understanding of the formation of massive black holes. The known population of IMBH remains small, with a few hundred candidates and…

Astrophysics of Galaxies · Physics 2020-02-12 Jorge Martínez-Palomera , Paulina Lira , India Bhalla-Ladd , Francisco Förster , Richard M. Plotkin

Machine Learning (ML) models are often complex and difficult to interpret due to their 'black-box' characteristics. Interpretability of a ML model is usually defined as the degree to which a human can understand the cause of decisions…

Methodology · Statistics 2020-06-25 Simon Kocbek , Primoz Kocbek , Leona Cilar , Gregor Stiglic

We introduce Matched Machine Learning, a framework that combines the flexibility of machine learning black boxes with the interpretability of matching, a longstanding tool in observational causal inference. Interpretability is paramount in…

Methodology · Statistics 2023-04-05 Marco Morucci , Cynthia Rudin , Alexander Volfovsky
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