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High-throughput technologies such as next generation sequencing allow biologists to observe cell function with unprecedented resolution, but the resulting datasets are too large and complicated for humans to understand without the aid of…

Applications · Statistics 2021-10-08 David S. Watson

Recent efforts in Machine Learning (ML) interpretability have focused on creating methods for explaining black-box ML models. However, these methods rely on the assumption that simple approximations, such as linear models or decision-trees,…

Machine Learning · Computer Science 2019-06-13 Owen Lahav , Nicholas Mastronarde , Mihaela van der Schaar

With the spread and rapid advancement of black box machine learning models, the field of interpretable machine learning (IML) or explainable artificial intelligence (XAI) has become increasingly important over the last decade. This is…

Globular clusters (GCs) are thought to harbor the long-sought population of intermediate-mass black holes (IMBHs). We present a systematic search for a putative IMBH in 81 Milky Way GCs, based on archival Chandra X-ray observations. We find…

High Energy Astrophysical Phenomena · Physics 2022-08-31 Zhao Su , Zhiyuan Li , Meicun Hou , Mengfei Zhang , Zhongqun Cheng

Prediction of survival in patients diagnosed with a brain tumour is challenging because of heterogeneous tumour behaviours and responses to treatment. Better estimations of prognosis would support treatment planning and patient support.…

Machine Learning · Computer Science 2021-06-18 Colleen E. Charlton , Michael Tin Chung Poon , Paul M. Brennan , Jacques D. Fleuriot

Intermediate-mass black holes (IMBHs) by definition have masses of $M_{\rm IMBH} \sim 10^{2-5}~M_\odot$, a range with few observational constraints. Finding IMBHs in globular star clusters (GCs) would validate a formation channel for…

Astrophysics of Galaxies · Physics 2021-09-08 J. M. Wrobel , T. J. Maccarone , J. C. A. Miller-Jones , K. E. Nyland

Globular clusters (GCs) have been at the heart of many longstanding questions in many sub-fields of astronomy and, as such, systematic identification of GCs in external galaxies has immense impacts. In this study, we take advantage of M87's…

There have been reports of possible detections of intermediate-mass black holes (IMBHs) in globular clusters (GCs). Empirically, there exists a tight correlation between the central supermassive black hole (SMBH) mass and the mean velocity…

High Energy Astrophysical Phenomena · Physics 2015-06-03 Yu-Qing Lou , Yi-Hong Wu

The existence of intermediate-mass black holes (IMBHs) in globular clusters (GCs) remains a crucial problem. Searching IMBHs in GCs reveals a discrepancy between radio observations and dynamical modelings: the upper mass limits constrained…

High Energy Astrophysical Phenomena · Physics 2015-06-16 Mou-Yuan Sun , Ya-Ling Jin , Wei-Min Gu , Tong Liu , Da-Bin Lin , Ju-Fu Lu

By means of a multimass isotropic and spherical model that includes the self-consistent treatment of a central intermediate-mass black hole (IMBH), the influence of this black hole on the morphological and physical properties of globular…

Astrophysics · Physics 2008-11-26 P. Miocchi

To learn about real world phenomena, scientists have traditionally used models with clearly interpretable elements. However, modern machine learning (ML) models, while powerful predictors, lack this direct elementwise interpretability (e.g.…

Machine Learning · Statistics 2024-07-16 Timo Freiesleben , Gunnar König , Christoph Molnar , Alvaro Tejero-Cantero

We discuss the potential of the gravitational microlensing method as a unique tool to detect unambiguous signals caused by intermediate-mass black holes in globular clusters. We select clusters near the line of sight to the Galactic Bulge…

Astrophysics of Galaxies · Physics 2016-06-15 N. Kains , D. M. Bramich , K. C. Sahu , A. Calamida

Deep learning approaches have recently been extensively explored for the prognostics of industrial assets. However, they still suffer from a lack of interpretability, which hinders their adoption in safety-critical applications. To improve…

Machine Learning · Computer Science 2024-05-29 Florent Forest , Katharina Rombach , Olga Fink

In this paper we explore the interplay between intermediate-mass black holes (IMBHs) and their nursing globular clusters (GCs), taking advantage of over 2000 Monte Carlo GC models. We find that the average density of IMBHs sphere of…

Astrophysics of Galaxies · Physics 2019-05-06 Manuel Arca Sedda , Abbas Askar , Mirek Giersz

In machine learning (ML), it is in general challenging to provide a detailed explanation on how a trained model arrives at its prediction. Thus, usually we are left with a black-box, which from a scientific standpoint is not satisfactory.…

Materials Science · Physics 2021-04-22 Luca M. Ghiringhelli

In this work, we address the following question: ``can we use the current cosmological simulations to identify intermediate-mass black holes (IMBHs) and quantify a putative population of wandering IMBHs?''. We compare wandering-IMBH counts…

Astrophysics of Galaxies · Physics 2025-04-30 Floor van Donkelaar , Lucio Mayer , Pedro R. Capelo , Tomas Tamfal

Interpretable machine learning (IML) becomes increasingly important in highly regulated industry sectors related to the health and safety or fundamental rights of human beings. In general, the inherently IML models should be adopted because…

Machine Learning · Computer Science 2021-11-03 Agus Sudjianto , Aijun Zhang

Understanding why machine learning models behave the way they do empowers both system designers and end-users in many ways: in model selection, feature engineering, in order to trust and act upon the predictions, and in more intuitive user…

Machine Learning · Statistics 2016-06-20 Marco Tulio Ribeiro , Sameer Singh , Carlos Guestrin

It has been assumed that intermediate-mass black holes (IMBHs) in globular clusters can only reside in the most centrally concentrated clusters, with a so-called `core-collapsed' density profile. While this would be a natural guess, it is…

Astrophysics · Physics 2009-11-10 Holger Baumgardt , Junichiro Makino , Piet Hut

Objectives: We study interpretable recidivism prediction using machine learning (ML) models and analyze performance in terms of prediction ability, sparsity, and fairness. Unlike previous works, this study trains interpretable models that…

Machine Learning · Statistics 2022-03-15 Caroline Wang , Bin Han , Bhrij Patel , Cynthia Rudin