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Optimizing the mRNA codon has an essential impact on gene expression for a specific target protein. It is an NP-hard problem; thus, exact solutions to such optimization problems become computationally intractable for realistic problem sizes…

Quantum Physics · Physics 2024-05-13 Hongfeng Zhang , Aritra Sarkar , Koen Bertels

Quantum algorithms for binary optimization problems have been the subject of extensive study. However, the application of quantum algorithms to integer optimization problems remains comparatively unexplored. In this paper, we study the…

We propose an inexact variable-metric proximal point algorithm to accelerate gradient-based optimization algorithms. The proposed scheme, called QNing can be notably applied to incremental first-order methods such as the stochastic…

Machine Learning · Statistics 2019-01-30 Hongzhou Lin , Julien Mairal , Zaid Harchaoui

The Quantum Approximate Optimization Algorithm can naturally be applied to combinatorial search problems on graphs. The quantum circuit has p applications of a unitary operator that respects the locality of the graph. On a graph with…

Quantum Physics · Physics 2020-04-21 Edward Farhi , David Gamarnik , Sam Gutmann

The Quantum Approximate Optimization Algorithm (QAOA) -- one of the leading algorithms for applications on intermediate-scale quantum processors -- is designed to provide approximate solutions to combinatorial optimization problems with…

Quantum Physics · Physics 2024-09-18 Pontus Vikstål , Laura García-Álvarez , Shruti Puri , Giulia Ferrini

Combinatorial optimization is among the main applications envisioned for near-term and fault-tolerant quantum computers. In this work, we consider a well-studied quantum algorithm for combinatorial optimization: the Quantum Approximate…

Quantum Physics · Physics 2020-11-12 Sami Boulebnane

One of the most basic computational problems is the task of finding a desired item in an ordered list of N items. While the best classical algorithm for this problem uses log_2 N queries to the list, a quantum computer can solve the problem…

Quantum Physics · Physics 2007-05-23 Andrew M. Childs , Andrew J. Landahl , Pablo A. Parrilo

Quantum computation appears to offer significant advantages over classical computation and this has generated a tremendous interest in the field. In this thesis we consider the application of quantum computers to scientific computing and…

Quantum Physics · Physics 2018-05-10 Stuart Hadfield

Variational quantum algorithms constitute one of the most widespread methods for using current noisy quantum computers. However, it is unknown if these heuristic algorithms provide any quantum-computational speedup, although we cannot…

The Quantum Approximate Optimization Algorithm (QAOA) is an algorithmic framework for finding approximate solutions to combinatorial optimization problems, derived from an approximation to the Quantum Adiabatic Algorithm (QAA). In solving…

Quantum Physics · Physics 2020-02-05 Yue Ruan , Samuel Marsh , Xilin Xue , Xi Li , Zhihao Liu , Jingbo Wang

Present-day, noisy, small or intermediate-scale quantum processors---although far from fault-tolerant---support the execution of heuristic quantum algorithms, which might enable a quantum advantage, for example, when applied to…

Motivated by economic dispatch and linearly-constrained resource allocation problems, this paper proposes a novel Distributed Approx-Newton algorithm that approximates the standard Newton optimization method. A main property of this…

Numerical Analysis · Computer Science 2017-03-24 Tor Anderson , Chin-Yao Chang , Sonia Martinez

This paper proposes a quantum-classical algorithm to evaluate and select classical artificial neural networks architectures. The proposed algorithm is based on a probabilistic quantum memory and the possibility to train artificial neural…

The quantum approximate optimization algorithm (QAOA) transforms a simple many-qubit wavefunction into one which encodes a solution to a difficult classical optimization problem. It does this by optimizing the schedule according to which…

Quantum Physics · Physics 2022-06-29 Yunlong Yu , Chenfeng Cao , Carter Dewey , Xiang-Bin Wang , Nic Shannon , Robert Joynt

Variational quantum algorithms (VQAs) provide a promising approach to achieving quantum advantage for practical problems on near-term noisy intermediate-scale quantum (NISQ) devices. Thus far, most studies on VQAs have focused on…

Quantum Physics · Physics 2023-10-06 Yutaro Enomoto , Keitaro Anai , Kenta Udagawa , Shuntaro Takeda

Combinatorial optimization is considered a promising class of problems in which quantum computers can show significant advantages. However, problems of practical relevance typically have more variables than current or foreseeable quantum…

Quantum Physics · Physics 2025-12-23 Mathias Schmid , Naeimeh Mohseni , Michael J. Hartmann

The quantum approximate optimization algorithm (QAOA) has numerous promising applications in solving the combinatorial optimization problems on near-term Noisy Intermediate Scalable Quantum (NISQ) devices. QAOA has a quantum-classical…

Quantum Physics · Physics 2022-02-17 Xinwei Lee , Yoshiyuki Saito , Dongsheng Cai , Nobuyoshi Asai

In recent years, quantum computing has emerged as a transformative force in the field of combinatorial optimization, offering novel approaches to tackling complex problems that have long challenged classical computational methods. Among…

This paper presents a novel quantum K-nearest neighbors (QKNN) algorithm, which offers improved performance over the classical k-NN technique by incorporating quantum computing (QC) techniques to enhance classification accuracy,…

Quantum Physics · Physics 2025-08-05 Asif Akhtab Ronggon , Md. Saifur Rahman

We study quantum computing algorithms for solving certain constrained resource allocation problems we coin as Mission Covering Optimization (MCO). We compare formulations of constrained optimization problems using Quantum Annealing…

Quantum Physics · Physics 2022-05-05 Massimiliano Cutugno , Annarita Giani , Paul M. Alsing , Laura Wessing , Austars Schnore