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Quantum annealers have been designed to propose near-optimal solutions to NP-hard optimization problems. However, the accuracy of current annealers such as the ones of D-Wave Systems, Inc., is limited by environmental noise and hardware…

Quantum Physics · Physics 2022-10-27 Aaron Barbosa , Elijah Pelofske , Georg Hahn , Hristo N. Djidjev

In this note, we describe an experiment on portfolio optimization using the Quadratic Unconstrained Binary Optimization (QUBO) formulation. The dataset we use is taken from a real-world problem for which a classical solution is currently…

We present a quantum annealing-based solution method for topology optimization (TO). In particular, we consider TO in a more general setting, i.e., applied to structures of continuum domains where designs are represented as distributed…

Numerical Analysis · Mathematics 2023-01-30 Zisheng Ye , Xiaoping Qian , Wenxiao Pan

Mixed-integer linear programming problems are extensively used in industry for a wide range of optimization tasks. However, as they get larger, they present computational challenges for classical solvers within practical time limits.…

Quantum Physics · Physics 2026-01-21 Sergio López-Baños , Elisabeth Lobe , Ontje Lünsdorf , Oriol Raventós

This paper presents a hybrid quantum-classical approach to prime factorization. The proposed algorithm is based on the Variational Quantum Eigensolver (VQE), which employs a classical optimizer to find the ground state of a given…

Quantum Physics · Physics 2025-03-21 Mona Sobhani , Yahui Chai , Tobias Hartung , Karl Jansen

Quantum computing is gaining popularity across a wide range of scientific disciplines due to its potential to solve long-standing computational problems that are considered intractable with classical computers. One promising area where…

Quantum Physics · Physics 2023-05-15 Benjamin C. B. Symons , David Galvin , Emre Sahin , Vassil Alexandrov , Stefano Mensa

AlphaFold has achieved groundbreaking advancements in protein structure prediction, exerting profound influence across biology, medicine, and drug discovery. However, its reliance on multiple sequence alignment (MSA) is inherently…

Quantum Physics · Physics 2025-06-03 Rong Chen , Quan-Xin Mei , Wen-Ding Zhao , Lin Yao , Hao-Xiang Yang , Shun-Yao Zhang , Jiao Chen , Hong-Lin Li

Quantum annealing has great promise in leveraging quantum mechanics to solve combinatorial optimisation problems. However, to realize this promise to it's fullest extent we must appropriately leverage the underlying physics. In this spirit,…

Quantum Physics · Physics 2020-12-10 Nicholas Chancellor

Optimization of electricity surplus is a crucial element for transmission power networks to reduce costs and efficiently use the available electricity across the network. In this paper we showed how to optimize such a network with quantum…

Quantum Physics · Physics 2022-12-06 Giuseppe Colucci , Stan van der Linde , Frank Phillipson

Quantum annealing machines based on superconducting qubits, which have the potential to solve optimization problems faster than digital computers, are of great interest not only to researchers but also to the general public. Here, we…

Quantum Physics · Physics 2018-10-22 T. Tanamoto , Y. Higashi , T. Marukame , J. Deguchi

Quantum optimization allows for up to exponential quantum speedups for specific, possibly industrially relevant problems. As the key algorithm in this field, we motivate and discuss the Quantum Approximate Optimization Algorithm (QAOA),…

Quantum Physics · Physics 2025-11-18 Jonas Stein , Maximilian Zorn , Leo Sünkel , Thomas Gabor

Quantum annealing aims to solve combinatorial optimization problems mapped on to Ising interactions between quantum spins. A critical factor that limits the success of a quantum annealer is its sensitivity to noise, and intensive research…

Quantum Physics · Physics 2019-01-29 Shruti Puri , Christian Kraglund Andersen , Arne L. Grimsmo , Alexandre Blais

Quantum Annealing (QA) relies on mixing two Hamiltonian terms, a simple driver and a complex problem Hamiltonian, in a linear combination. The time-dependent schedule for this mixing is often taken to be linear in time: improving on this…

Quantum Physics · Physics 2024-09-17 Giovanni Pecci , Ruiyi Wang , Pietro Torta , Glen Bigan Mbeng , Giuseppe Santoro

Solving continuous variable optimization problems by factorization machine quantum annealing (FMQA) demonstrates the potential of Ising machines to be extended as a solver for integer and real optimization problems. However, the details of…

Quantum Physics · Physics 2024-07-08 Katsuhiro Endo , Kazuaki Z. Takahashi

We propose a novel method for reducing the number of variables in quadratic unconstrained binary optimization problems, using a quantum annealer (or any sampler) to fix the value of a large portion of the variables to values that have a…

Quantum Physics · Physics 2017-09-26 Hamed Karimi , Gili Rosenberg

The Closest String Problem is an NP-complete problem which appears more commonly in bioinformatics and coding theory. Less surprisingly, classical approaches have been pursued with two prominent algorithms being the genetic algorithm and…

Quantum Physics · Physics 2023-10-20 Chandeepa Dissanayake

Quantum annealing (QA) and Quantum Alternating Operator Ansatz (QAOA) are both heuristic quantum algorithms intended for sampling optimal solutions of combinatorial optimization problems. In this article we implement a rigorous direct…

Quantum Physics · Physics 2023-08-31 Elijah Pelofske , Andreas Bärtschi , Stephan Eidenbenz

Quantum block encoding (QBE) is a crucial step in the development of most quantum algorithms, as it provides an embedding of a given matrix into a suitable larger unitary matrix. Historically, the development of efficient techniques for QBE…

Quantum Physics · Physics 2026-03-20 Giacomo Antonioli , Paola Boito , Gianna M. Del Corso , Margherita Porcelli

Current quantum computing devices have different strengths and weaknesses depending on their architectures. This means that flexible approaches to circuit design are necessary. We address this task by introducing a novel space-efficient…

Parallel Quantum Annealing is a technique to solve multiple optimization problems simultaneously. Parallel quantum annealing aims to optimize the utilization of available qubits on a quantum topology by addressing multiple independent…

Quantum Physics · Physics 2024-03-12 Arit Kumar Bishwas , Anuraj Som , Saurabh Choudhary