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For a one-locus haploid infinite population with discrete generations, the celebrated Kingman's model describes the evolution of fitness distributions under the competition of selection and mutation, with a constant mutation probability.…

Probability · Mathematics 2021-06-01 Linglong Yuan

Near the beginning of the century, Wright and Fisher devised an elegant, mathematically tractable model of gene reproduction and replacement that laid the foundation for contemporary population genetics. The Wright-Fisher model and its…

Probability · Mathematics 2013-12-23 Todd L. Parsons

Evolutionary graph theory studies the evolutionary dynamics in a population structure given as a connected graph. Each node of the graph represents an individual of the population, and edges determine how offspring are placed. We consider…

Neural and Evolutionary Computing · Computer Science 2017-06-22 Krishnendu Chatterjee , Rasmus Ibsen-Jensen , Martin A. Nowak

Sufficient dimension reduction (SDR) is a popular class of regression methods which aim to find a small number of linear combinations of covariates that capture all the information of the responses i.e., a central subspace. The majority of…

Methodology · Statistics 2024-10-15 Linh H. Nghiem , F. K. C. Hui

To complete a previous paper, the probability density functions of the center-of-gravity as positioning algorithm are derived with classical methods. These methods, as suggested by the textbook of Probability, require the preliminary…

Statistical Mechanics · Physics 2020-06-05 Gregorio Landi , Giovanni E. Landi

In this paper, we consider several efficient data structures for the problem of sampling from a dynamically changing discrete probability distribution, where some prior information is known on the distribution of the rates, in particular…

Computational Engineering, Finance, and Science · Computer Science 2021-10-13 Federico D'Ambrosio , Hans L. Bodlaender , Gerard T. Barkema

In this paper we study the following one-dimensional reaction-diffusion problem $$ u_t+(-\Delta)^s u=f(x-c t, u) \;\:\textrm{ in } \mathbb{R}\times (0,+\infty), $$ where $s>\frac{1}{2}$, $c \in \mathbb{R}$ is a prescribed velocity, and $f$…

Analysis of PDEs · Mathematics 2025-09-29 Sebastián Flores-Sepúlveda , Gabrielle Nornberg , Alexander Quaas

Understanding the temporal spread of gene drive alleles -- alleles that bias their own transmission -- through modeling is essential before any field experiments. In this paper, we present a deterministic reaction-diffusion model describing…

Analysis of PDEs · Mathematics 2023-11-01 Léna Kläy , Léo Girardin , Vincent Calvez , Florence Débarre

We establish the global existence of weak solutions for a two-species cross-diffusion system, set on the 1-dimensional flat torus, in which the evolution of each species is governed by two mechanisms. The first of these is a diffusion which…

Analysis of PDEs · Mathematics 2025-04-28 Alpár R. Mészáros , Guy Parker

Many important statistical models fall outside classical moment-based methods due to the non-existence of moments or moment generating functions. We propose a generalised probabilistic framework in which densities are replaced by pairs…

Probability · Mathematics 2026-05-22 R. Labouriau

We introduce a theory of sequential causal inference in which learners in a chain estimate a structural model from their upstream teacher and then pass samples from the model to their downstream student. It extends the population dynamics…

Populations and Evolution · Quantitative Biology 2012-02-28 James P. Crutchfield , Sean Whalen

We formulate pure characteristics demand models under uncertainties of probability distributions as distributionally robust mathematical programs with stochastic complementarity constraints (DRMP-SCC). For any fixed first-stage variable and…

Optimization and Control · Mathematics 2021-02-10 Jie Jiang , Xiaojun Chen

The reparameterization trick enables optimizing large scale stochastic computation graphs via gradient descent. The essence of the trick is to refactor each stochastic node into a differentiable function of its parameters and a random…

Machine Learning · Computer Science 2017-03-07 Chris J. Maddison , Andriy Mnih , Yee Whye Teh

Evolutionary graph theory studies the evolutionary dynamics of populations structured on graphs. A central problem is determining the probability that a small number of mutants overtake a population. Currently, Monte Carlo simulations are…

Computer Science and Game Theory · Computer Science 2013-01-14 Paulo Shakarian , Patrick Roos , Geoffrey Moores

The majority of theoretical analyses of evolutionary algorithms in the discrete domain focus on binary optimization algorithms, even though black-box optimization on the categorical domain has a lot of practical applications. In this paper,…

Neural and Evolutionary Computing · Computer Science 2024-07-11 Ryoki Hamano , Kento Uchida , Shinichi Shirakawa , Daiki Morinaga , Youhei Akimoto

This paper introduces an upper bound on the absolute difference between: (a) the cumulative distribution function (CDF) of the sum of a finite number of independent and identically distributed random variables with finite absolute third…

Information Theory · Computer Science 2020-07-22 Dadja Anade , Jean-Marie Gorce , Philippe Mary , Samir Perlaza

We propose a model for diffusion-limited annihilation of two species, $A+B\to A$ or $B$, where the motion of the particles is subject to a drift. For equal initial concentrations of the two species, the density follows a power-law decay for…

Condensed Matter · Physics 2010-10-12 Daniel ben-Avraham , Vladimir Privman , Dexin Zhong

By exploiting an analogy between population genetics and statistical mechanics, we study the evolution of a polygenic trait under stabilizing selection, mutation, and genetic drift. This requires us to track only four macroscopic variables,…

Populations and Evolution · Quantitative Biology 2010-11-18 Harold P. de Vladar , Nick Barton

An equation describing the evolution of phenotypic distribution is derived using methods developed in statistical physics. The equation is solved by using the singular perturbation method, and assuming that the number of bases in the…

Populations and Evolution · Quantitative Biology 2009-11-13 Katsuhiko Sato , Kunihiko Kaneko

Natural phenomena frequently involve a very large number of interacting molecules moving in confined regions of space. Cellular transport by motor proteins is an example of such collective behavior. We derive a deterministic compartmental…

Subcellular Processes · Quantitative Biology 2017-11-01 Yoram Zarai , Michael Margaliot , Anatoly B. Kolomeisky