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Biomembranes play a central role in various phenomena like locomotion of cells, cell-cell interactions, packaging of nutrients, and in maintaining organelle morphology and functionality. During these processes, the membranes undergo…

Quantitative Methods · Quantitative Biology 2021-12-01 Debabrata Auddya , Xiaoxuan Zhang , Rahul Gulati , Ritvik Vasan , Krishna Garikipati , Padmini Rangamani , Shiva Rudraraju

Recent developments in lipid membrane models for simulations are reviewed. To reduce computational costs, various coarse-grained molecular models have been proposed. Among them, implicit solvent (solvent-free) molecular models are…

Soft Condensed Matter · Physics 2015-05-13 Hiroshi Noguchi

In this paper, we present a novel numerical scheme for simulating deformable and extensible capsules suspended in a Stokesian fluid. The main feature of our scheme is a partition-of-unity (POU) based representation of the surface that…

Numerical Analysis · Mathematics 2024-04-09 Dhwanit Agarwal , George Biros

We present a general simulation approach for incompressible fluid--structure interactions in a fully Eulerian framework using the reference map technique (RMT). The approach is suitable for modeling one or more rigid or finitely-deformable…

Fluid Dynamics · Physics 2022-03-14 Xiaolin Wang , Ken Kamrin , Chris H. Rycroft

We present a numerical method specifically designed for simulating three-dimensional fluid--structure interaction (FSI) problems based on the reference map technique (RMT). The RMT is a fully Eulerian FSI numerical method that allows fluids…

Fluid Dynamics · Physics 2022-05-18 Yuexia L. Lin , Nicholas J. Derr , Chris H. Rycroft

We describe a numerical method to simulate an elastic shell immersed in a viscous incompressible fluid. The method is developed as an extension of the immersed boundary method using shell equations based on the Kirchhoff-Love and the planar…

Numerical Analysis · Mathematics 2025-10-20 E. Givelberg

Viscoelastic surface rheology plays an important role in multiphase systems. A typical example is the actin cortex which surrounds most animal cells. It shows elastic properties for short time scales and behaves viscous for longer time…

Fluid Dynamics · Physics 2021-06-01 Eloy de Kinkelder , Leonard Sagis , Sebastian Aland

Cell proliferation, apoptosis, and myosin-dependent contraction can generate elastic stress and strain in living tissues, which may be dissipated by internal rearrangement through cell topological transition and cytoskeletal reorganization.…

Biological Physics · Physics 2021-12-07 Chaozhen Wei , Min Wu

A three-dimensional deformable capsule convected through a square duct with a corner is studied via numerical simulations. We develop an accelerated boundary integral implementation adapted to general geometries and boundary conditions. A…

Fluid Dynamics · Physics 2015-06-22 Lailai Zhu , Luca Brandt

In this paper, we propose a linear and monolithic finite element method for the approximation of an incompressible viscous fluid interacting with an elastic and deforming plate. We use the arbitrary Lagrangian-Eulerian (ALE) approach that…

Numerical Analysis · Mathematics 2023-01-13 Sebastian Schwarzacher , Bangwei She , Karel Tuma

A computational approach is introduced for the study of the rheological properties of complex fluids and soft materials. The approach allows for a consistent treatment of microstructure elastic mechanics, hydrodynamic coupling, thermal…

Soft Condensed Matter · Physics 2023-02-28 P. J. Atzberger

This paper introduces a sharp interface method to simulate fluid-structure interaction (FSI) involving rigid bodies immersed in viscous incompressible fluids. The capabilities of this methodology are demonstrated for a range of benchmark…

The deformation of an initially spherical capsule, freely suspended in simple shear flow, can be computed analytically in the limit of small deformations [D. Barthes-Biesel, J. M. Rallison, The Time-Dependent Deformation of a Capsule Freely…

Soft Condensed Matter · Physics 2010-08-10 Timm Krüger , Fathollah Varnik , Dierk Raabe

In this work, we present a computational formulation based on continuum mechanics to study the interaction of fluid membranes embedded with semiflexible filaments. This is motivated by systems in membrane biology, such as cytoskeletal…

Numerical Analysis · Mathematics 2023-12-21 Basant Lal Sharma , Luigi E. Perotti , Sanjay Dharmavaram

Fluid deformable surfaces are ubiquitous in cell and tissue biology, including lipid bilayers, the actomyosin cortex, or epithelial cell sheets. These interfaces exhibit a complex interplay between elasticity, low Reynolds number…

Fluid Dynamics · Physics 2019-06-12 Alejandro Torres-Sánchez , Daniel Millán , Marino Arroyo

This paper presents a general and robust method for the fluid-structure interaction of membranes and shells undergoing large displacement and large added-mass effects by coupling an immersed-boundary method with a shell finite-element…

Fluid Dynamics · Physics 2023-08-15 Marin Lauber , Gabriel D. Weymouth , Georges Limbert

We propose a sharp-interface model for a hyperelastic material consisting of two phases. In this model, phase interfaces are treated in the deformed configuration, resulting in a fully Eulerian interfacial energy. In order to penalize large…

Analysis of PDEs · Mathematics 2024-02-16 Katharina Brazda , Martin Kružík , Fabian Rupp , Ulisse Stefanelli

The development of turbulence closure models, parametrizing the influence of small non-resolved scales on the dynamics of large resolved ones, is an outstanding theoretical challenge with vast applicative relevance. We present a closure,…

Fluid Dynamics · Physics 2024-06-26 Giulio Ortali , Alessandro Corbetta , Gianluigi Rozza , Federico Toschi

In spite of the great success that all-atom molecular dynamics simulations have seen in revealing the nature of the lipid bilayer, the interplay between a membrane's curvature and dynamics remains elusive. This is largely due to the…

Soft Condensed Matter · Physics 2022-07-26 Christopher Kang , Kazuumi Fujioka , Rui Sun

Soft solids in fluids find wide range of applications in science and engineering, especially in the study of biological tissues and membranes. In this study, an Eulerian finite volume approach has been developed to simulate fully resolved…

Computational Physics · Physics 2019-09-17 Suhas S. Jain , Ken Kamrin , Ali Mani