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We consider the problem of estimation in Hidden Markov models with finite state space and nonparametric emission distributions. Efficient estimators for the transition matrix are exhibited, and a semiparametric Bernstein-von Mises result is…

Statistics Theory · Mathematics 2023-03-09 Daniel Moss , Judith Rousseau

We develop and evaluate MlPET, a fast localized machine learning approach for probabilistic PET image analysis addressing the noise-resolution trade-off in conventional reconstructions. MlPET replaces computationally demanding Markov chain…

Medical Physics · Physics 2026-01-27 Thomas Mejer Hansen , Nana Christensen , Mikkel Vendelbo

Stochastic differential equations (SDEs) provide a flexible framework for modeling temporal dynamics in partially observed systems. A central task is to calibrate such models from data, which requires inferring latent trajectories and…

Machine Learning · Statistics 2026-05-08 Yu Wang , Arnab Ganguly

Uncertainty quantification is a critical missing component in radio interferometric imaging that will only become increasingly important as the big-data era of radio interferometry emerges. Since radio interferometric imaging requires…

Instrumentation and Methods for Astrophysics · Physics 2018-09-12 Xiaohao Cai , Marcelo Pereyra , Jason D. McEwen

Posterior inference from pulsar observations in the form of light curves is commonly performed using Markov chain Monte Carlo methods, which are accurate but computationally expensive. We introduce a framework that accelerates posterior…

Accurate pedestrian trajectory prediction is crucial for autonomous systems operating in complex environments, such as modular buses and delivery robots in suburban or semi-structured areas. Social Spatio-Temporal Graph Convolutional Neural…

Robotics · Computer Science 2026-05-19 Yuzhou Liu , Cristina Olaverri-Monreal

Sample-based Bayesian inference provides a route to uncertainty quantification in the geosciences, and inverse problems in general, though is very computationally demanding in the naive form that requires simulating an accurate computer…

Computation · Statistics 2019-04-12 Tiangang Cui , Colin Fox , Michael J O'Sullivan

Positron emission tomography (PET) is a classical imaging technique to reconstruct the mass distribution of a radioactive material. If the mass distribution is static, this essentially leads to inversion of the X-ray transform. However, if…

Optimization and Control · Mathematics 2023-11-30 Marco Mauritz , Bernhard Schmitzer , Benedikt Wirth

This paper aims at mathematically modeling a new multi-physics conductivity imaging system incorporating mechanical vibrations simultaneously applied to an imaging object together with current injections. We perturb the internal…

Medical Physics · Physics 2014-05-20 Habib Ammari , Eunjung Lee , Hyeuknam Kwon , Jin Keun Seo , Eung Je Woo

We propose a novel adaptive importance sampling scheme for Bayesian inversion problems where the inference of the variables of interest and the power of the data noise is split. More specifically, we consider a Bayesian analysis for the…

Computation · Statistics 2021-07-27 L. Martino , F. Llorente , E. Curbelo , J. Lopez-Santiago , J. Miguez

We study Bayesian methods for large-scale linear inverse problems, focusing on the challenging task of hyperparameter estimation. Typical hierarchical Bayesian formulations that follow a Markov Chain Monte Carlo approach are possible for…

Numerical Analysis · Mathematics 2024-01-05 Khalil A Hall-Hooper , Arvind K Saibaba , Julianne Chung , Scot M Miller

Inverse problems, i.e., estimating parameters of physical models from experimental data, are ubiquitous in science and engineering. The Bayesian formulation is the gold standard because it alleviates ill-posedness issues and quantifies…

Machine Learning · Statistics 2024-05-28 Sharmila Karumuri , Ilias Bilionis

Regularization of inverse problems is of paramount importance in computational imaging. The ability of neural networks to learn efficient image representations has been recently exploited to design powerful data-driven regularizers. While…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Maud Biquard , Marie Chabert , Florence Genin , Christophe Latry , Thomas Oberlin

Low-dose positron emission tomography (PET) image reconstruction methods have potential to significantly improve PET as an imaging modality. Deep learning provides a promising means of incorporating prior information into the image…

Computer Vision and Pattern Recognition · Computer Science 2024-09-11 Cameron Dennis Pain , Yasmeen George , Alex Fornito , Gary Egan , Zhaolin Chen

Bayesian learning in undirected graphical models|computing posterior distributions over parameters and predictive quantities is exceptionally difficult. We conjecture that for general undirected models, there are no tractable MCMC (Markov…

Machine Learning · Computer Science 2012-07-19 Iain Murray , Zoubin Ghahramani

Noninvasive reconstruction of cardiac electrical activity from surface electrocardiograms (ECG) involves solving an ill-posed inverse problem. Cardiac electrophysiological (EP) models have been used as important a priori knowledge to…

Image and Video Processing · Electrical Eng. & Systems 2019-05-14 Sandesh Ghimire , John L Sapp , Milan Horacek , Linwei Wang

Parameter inference is a fundamental problem in data-driven modeling. Given observed data that is believed to be a realization of some parameterized model, the aim is to find parameter values that are able to explain the observed data. In…

Data Structures and Algorithms · Computer Science 2016-04-20 Carlo Albert , Simone Ulzega , Ruedi Stoop

High-throughput characterization often requires estimating parameters and model dimension from experimental data of limited quantity and quality. Such data may result in an ill-posed inverse problem, where multiple sets of parameters and…

Quantum Physics · Physics 2026-04-08 Abigail N. Poteshman , Jiwon Yun , Tim H. Taminiau , Giulia Galli

For whole-body (WB) kinetic modeling based on a typical PET scanner, a multi-pass multi-bed scanning protocol is necessary given the limited axial field-of-view. Such a protocol introduces loss of early-dynamics in time-activity curves…

Medical Physics · Physics 2024-05-14 Kyung-Nam Lee , Arman Rahmim , Carlos Uribe

In this article we consider Bayesian parameter inference associated to partially-observed stochastic processes that start from a set B0 and are stopped or killed at the first hitting time of a known set A. Such processes occur naturally…

Computation · Statistics 2012-01-19 Ajay Jasra , Nikolas Kantas
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