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Cardiovascular disease (CVD) is a leading cause of mortality worldwide. Electrocardiograms (ECGs) are the most widely used non-invasive tool for cardiac assessment, yet large, well-annotated ECG corpora are scarce due to cost, privacy, and…

Machine Learning · Computer Science 2025-11-14 Xiaoda Wang , Kaiqiao Han , Yuhao Xu , Xiao Luo , Yizhou Sun , Wei Wang , Carl Yang

Aside from offering state-of-the-art performance in medical image generation, denoising diffusion probabilistic models (DPM) can also serve as a representation learner to capture semantic information and potentially be used as an image…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Chun-Mei Feng

Low-dose Positron Emission Tomography (PET) imaging presents a significant challenge due to increased noise and reduced image quality, which can compromise its diagnostic accuracy and clinical utility. Denoising diffusion probabilistic…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Boxiao Yu , Savas Ozdemir , Jiong Wu , Yizhou Chen , Ruogu Fang , Kuangyu Shi , Kuang Gong

Tabular data plays a crucial role in various domains but often suffers from missing values, thereby curtailing its potential utility. Traditional imputation techniques frequently yield suboptimal results and impose substantial computational…

Machine Learning · Computer Science 2024-03-22 Yizhu Wen , Kai Yi , Jing Ke , Yiqing Shen

Photoplethysmogram (PPG) and electrocardiogram (ECG) are commonly recorded in intesive care unit (ICU) and operating room (OR). However, the high incidence of poor, incomplete, and inconsistent signal quality, can lead to false alarms or…

Machine Learning · Computer Science 2025-09-16 Zongheng Guo , Tao Chen , Manuela Ferrario

Objective: Electrocardiogram (ECG) signals commonly suffer noise interference, such as baseline wander. High-quality and high-fidelity reconstruction of the ECG signals is of great significance to diagnosing cardiovascular diseases.…

Signal Processing · Electrical Eng. & Systems 2023-01-19 Huayu Li , Gregory Ditzler , Janet Roveda , Ao Li

Health risk prediction is one of the fundamental tasks under predictive modeling in the medical domain, which aims to forecast the potential health risks that patients may face in the future using their historical Electronic Health Records…

Machine Learning · Computer Science 2023-10-09 Yuan Zhong , Suhan Cui , Jiaqi Wang , Xiaochen Wang , Ziyi Yin , Yaqing Wang , Houping Xiao , Mengdi Huai , Ting Wang , Fenglong Ma

This paper introduces a novel speech enhancement (SE) approach based on a denoising diffusion probabilistic model (DDPM), termed Guided diffusion for speech enhancement (GDiffuSE). In contrast to conventional methods that directly map noisy…

Sound · Computer Science 2026-03-03 Efrayim Yanir , David Burshtein , Sharon Gannot

While electroencephalogram (EEG) has been a crucial tool for monitoring the brain and diagnosing neurological disorders (e.g., epilepsy), learning meaningful representations from raw EEG signals remains challenging due to limited…

Machine Learning · Computer Science 2025-09-03 Jia Hong Puah , Sim Kuan Goh , Ziwei Zhang , Zixuan Ye , Chow Khuen Chan , Kheng Seang Lim , Si Lei Fong , Kok Sin Woon , Cuntai Guan

Electroencephalography (EEG) plays a significant role in the Brain Computer Interface (BCI) domain, due to its non-invasive nature, low cost, and ease of use, making it a highly desirable option for widespread adoption by the general…

Signal Processing · Electrical Eng. & Systems 2023-03-13 Giulio Tosato , Cesare M. Dalbagno , Francesco Fumagalli

Due to various physical degradation factors and limited counts received, PET image quality needs further improvements. The denoising diffusion probabilistic models (DDPM) are distribution learning-based models, which try to transform a…

Image and Video Processing · Electrical Eng. & Systems 2022-09-15 Kuang Gong , Keith A. Johnson , Georges El Fakhri , Quanzheng Li , Tinsu Pan

Despite the proliferation of generative models, achieving fast sampling during inference without compromising sample diversity and quality remains challenging. Existing models such as Denoising Diffusion Probabilistic Models (DDPM) deliver…

Machine Learning · Computer Science 2023-10-12 Yanwu Xu , Mingming Gong , Shaoan Xie , Wei Wei , Matthias Grundmann , Kayhan Batmanghelich , Tingbo Hou

Denoising diffusion probabilistic models (DDPM) are a class of generative models which have recently been shown to produce excellent samples. We show that with a few simple modifications, DDPMs can also achieve competitive log-likelihoods…

Machine Learning · Computer Science 2021-02-22 Alex Nichol , Prafulla Dhariwal

Generative artificial intelligence (AI) has been playing an important role in various domains. Leveraging its high capability to generate high-fidelity and diverse synthetic data, generative AI is widely applied in diagnostic tasks, such as…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Yifan Jiang , Ahmad Shariftabrizi , Venkata SK. Manem

Background and Objective: Vital sign monitoring in the Intensive Care Unit (ICU) is crucial for enabling prompt interventions for patients. This underscores the need for an accurate predictive system. Therefore, this study proposes a novel…

Machine Learning · Computer Science 2024-04-05 Ping Chang , Huayu Li , Stuart F. Quan , Shuyang Lu , Shu-Fen Wung , Janet Roveda , Ao Li

Multi-channel EEG signals are commonly used for the diagnosis and assessment of diseases such as epilepsy. Currently, various EEG diagnostic algorithms based on deep learning have been developed. However, most research efforts focus solely…

Signal Processing · Electrical Eng. & Systems 2024-10-24 Zekun Jiang , Wei Dai , Qu Wei , Ziyuan Qin , Kang Li , Le Zhang

Diffusion models are increasingly being utilised to create synthetic tabular and time series data for privacy-preserving augmentation. Tabular Denoising Diffusion Probabilistic Models (TabDDPM) generate high-quality synthetic data from…

Machine Learning · Computer Science 2026-04-08 Umang Dobhal , Christina Garcia , Sozo Inoue

Advances in microscopy imaging enable researchers to visualize structures at the nanoscale level thereby unraveling intricate details of biological organization. However, challenges such as image noise, photobleaching of fluorophores, and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Pamela Osuna-Vargas , Maren H. Wehrheim , Lucas Zinz , Johanna Rahm , Ashwin Balakrishnan , Alexandra Kaminer , Mike Heilemann , Matthias Kaschube

An important paradigm in smart health is developing diagnosis tools and monitoring a patient's heart activity through processing Electrocardiogram (ECG) signals is a key example, sue to high mortality rate of heart-related disease. However,…

Signal Processing · Electrical Eng. & Systems 2018-11-02 Jiaming Chen , Ali Valehi , Abolfazl Razi

Electrocardiography (ECG) signals are frequently degraded by noise, limiting their clinical reliability in both conventional and wearable settings. Existing methods for addressing ECG noise, relying on artifact classification or denoising,…

Signal Processing · Electrical Eng. & Systems 2025-07-23 Tae-Seong Han , Jae-Wook Heo , Hakseung Kim , Cheol-Hui Lee , Hyub Huh , Eue-Keun Choi , Hye Jin Kim , Dong-Joo Kim