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The conditional survival function of a time-to-event outcome subject to censoring and truncation is a common target of estimation in survival analysis. This parameter may be of scientific interest and also often appears as a nuisance in…

Methodology · Statistics 2024-08-20 Charles J. Wolock , Peter B. Gilbert , Noah Simon , Marco Carone

Chronic diseases are long-lasting conditions that require lifelong medical attention. Using big EMR data, we have developed early disease risk prediction models for five common chronic diseases: diabetes, hypertension, CKD, COPD, and…

Machine Learning · Computer Science 2026-03-13 Shaheer Ahmad Khan , Muhammad Usamah Shahid , Muddassar Farooq

Accurate prediction of time-to-event outcomes is critical for clinical decision-making, treatment planning, and resource allocation in modern healthcare. While classical survival models such as Cox remain widely adopted in standard…

Machine Learning · Computer Science 2026-02-03 Marina Mastroleo , Alberto Archetti , Federico Mastroleo , Matteo Matteucci

In response to the COVID-19 pandemic, the integration of interpretable machine learning techniques has garnered significant attention, offering transparent and understandable insights crucial for informed clinical decision making. This…

Machine Learning · Computer Science 2024-09-10 Jinzhi Shen , Ke Ma

While analysing time-to-event data, it is possible that a certain fraction of subjects will never experience the event of interest and they are said to be cured. When this feature of survival models is taken into account, the models are…

Methodology · Statistics 2020-01-27 Khandoker Akib Mohammad , Yuichi Hirose , Budhi Surya , Yuan Yao

Purpose: The application of Cox Proportional Hazards (CoxPH) models to survival data and the derivation of Hazard Ratio (HR) is well established. While nonlinear, tree-based Machine Learning (ML) models have been developed and applied to…

Machine Learning · Computer Science 2021-04-06 Sameer Sundrani , James Lu

Survival analysis is a widely known method for predicting the likelihood of an event over time. The challenge of dealing with censored samples still remains. Traditional methods, such as the Cox Proportional Hazards (CPH) model, hinge on…

Machine Learning · Computer Science 2025-01-10 Chanon Puttanawarut , Panu Looareesuwan , Romen Samuel Wabina , Prut Saowaprut

In statistics, time-to-event analysis methods traditionally focus on the estimation of hazards. In recent years, machine learning methods have been proposed to directly predict the event times. We propose a method based on vine copula…

Methodology · Statistics 2021-11-16 Shenyi Pan , Harry Joe

Predictive modelling is vital to guide preventive efforts. Whilst large-scale prospective cohort studies and a diverse toolkit of available machine learning (ML) algorithms have facilitated such survival task efforts, choosing the…

The Cox model, which remains as the first choice in analyzing time-to-event data even for large datasets, relies on the proportional hazards (PH) assumption. When survival data arrive sequentially in chunks, a fast and minimally storage…

Methodology · Statistics 2020-11-24 Yishu Xue , HaiYing Wang , Jun Yan , Elizabeth D. Schifano

The use of massive survival data has become common in survival analysis. In this study, a subsampling algorithm is proposed for the Cox proportional hazards model with time-dependent covariates when the sample is extraordinarily large but…

Computation · Statistics 2023-02-07 Nan Qiao , Wangcheng Li , Feng Xiao , Cunjie Lin , Yong Zhou

The COVID-19 pandemic has strained global public health, necessitating accurate diagnosis and intervention to control disease spread and reduce mortality rates. This paper introduces an interpretable deep survival prediction model designed…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Zhusi Zhong , Jie Li , Zhuoqi Ma , Scott Collins , Harrison Bai , Paul Zhang , Terrance Healey , Xinbo Gao , Michael K. Atalay , Zhicheng Jiao

This work bridges the gap between staggered adoption designs and survival analysis to estimate causal effects in settings with time-varying treatments, addressing a fundamental challenge in medical research exemplified by the Stanford Heart…

Methodology · Statistics 2025-03-04 Xiang Meng , Iavor Bojinov

When dealing with right-censored data, where some outcomes are missing due to a limited observation period, survival analysis -- known as time-to-event analysis -- focuses on predicting the time until an event of interest occurs. Multiple…

Machine Learning · Statistics 2024-10-23 Julie Alberge , Vincent Maladière , Olivier Grisel , Judith Abécassis , Gaël Varoquaux

With increasing interest in applying machine learning to develop healthcare solutions, there is a desire to create interpretable deep learning models for survival analysis. In this paper, we extend the Neural Additive Model (NAM) by…

Machine Learning · Computer Science 2022-11-18 Matthew Peroni , Marharyta Kurban , Sun Young Yang , Young Sun Kim , Hae Yeon Kang , Ji Hyun Song

Survival Regression (SuR) is a key technique for modeling time to event in important applications such as clinical trials and semiconductor manufacturing. Currently, SuR algorithms belong to one of three classes: non-linear black-box --…

Machine Learning · Computer Science 2025-04-09 Luigi Rovito , Marco Virgolin

Traditional survival models such as the Cox proportional hazards model are typically based on scalar or categorical clinical features. With the advent of increasingly large image datasets, it has become feasible to incorporate quantitative…

Computer Vision and Pattern Recognition · Computer Science 2020-01-09 Christoph Haarburger , Philippe Weitz , Oliver Rippel , Dorit Merhof

While there are many well-developed data science methods for classification and regression, there are relatively few methods for working with right-censored data. Here, we present "survival stacking": a method for casting survival analysis…

Methodology · Statistics 2021-07-29 Erin Craig , Chenyang Zhong , Robert Tibshirani

Survival analysis is a crucial semi-supervised task in machine learning with numerous real-world applications, particularly in healthcare. Currently, the most common approach to survival analysis is based on Cox's partial likelihood, which…

Machine Learning · Computer Science 2023-04-27 Andre Vauvelle , Benjamin Wild , Aylin Cakiroglu , Roland Eils , Spiros Denaxas

Survival analysis is a hotspot in statistical research for modeling time-to-event information with data censorship handling, which has been widely used in many applications such as clinical research, information system and other fields with…

Machine Learning · Computer Science 2018-11-14 Kan Ren , Jiarui Qin , Lei Zheng , Zhengyu Yang , Weinan Zhang , Lin Qiu , Yong Yu