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High dimensional data can contain multiple scales of variance. Analysis tools that preferentially operate at one scale can be ineffective at capturing all the information present in this cross-scale complexity. We propose a multiscale joint…

Machine Learning · Statistics 2022-03-15 Daniel Sousa , Christopher Small

Algebraic topology has been widely applied to point cloud data to capture geometric shapes and topological structures. However, its application to genome sequence analysis remains rare. In this work, we propose topological sequence analysis…

Algebraic Topology · Mathematics 2025-07-09 Jian Liu , Li Shen , Dong Chen , Guo-Wei Wei

Single-cell RNA-seq provides detailed molecular snapshots of individual cells but is notoriously noisy. Variability stems from biological differences and technical factors, such as amplification bias and limited RNA capture efficiency,…

Machine Learning · Computer Science 2026-02-27 Victor Chardès

Principal Component Analysis (PCA) has been widely used for dimensionality reduction and feature extraction. Robust PCA (RPCA), under different robust distance metrics, such as l1-norm and l2, p-norm, can deal with noise or outliers to some…

Machine Learning · Computer Science 2021-06-29 Zhao Kang , Hongfei Liu , Jiangxin Li , Xiaofeng Zhu , Ling Tian

Graph neural networks (GNN) are an effective framework that exploit inter-relationships within graph-structured data for learning. Principal component analysis (PCA) involves the projection of data on the eigenspace of the covariance matrix…

Machine Learning · Computer Science 2023-01-18 Saurabh Sihag , Gonzalo Mateos , Corey McMillan , Alejandro Ribeiro

The widespread enthusiasm for deep learning has recently expanded into the domain of tabular data. Recognizing that the advancement in deep tabular methods is often inspired by classical methods, e.g., integration of nearest neighbors into…

Machine Learning · Computer Science 2025-03-04 Han-Jia Ye , Huai-Hong Yin , De-Chuan Zhan , Wei-Lun Chao

The rapidly growing field of single-cell transcriptomic sequencing (scRNAseq) presents challenges for data analysis due to its massive datasets. A common method in manifold learning consists in hypothesizing that datasets lie on a lower…

Kernel principal component analysis (KPCA) is a well-recognized nonlinear dimensionality reduction method that has been widely used in nonlinear fault detection tasks. As a kernel trick-based method, KPCA inherits two major problems. First,…

Machine Learning · Computer Science 2024-10-28 Zelin Ren , Xuebing Yang , Yuchen Jiang , Wensheng Zhang

Graph-based representations of point-cloud data are widely used in data science and machine learning, including epsilon-graphs that contain edges between pairs of data points that are nearer than epsilon and kNN-graphs that connect each…

Algebraic Topology · Mathematics 2022-06-13 Minh Quang Le , Dane Taylor

Single-cell RNA sequencing (scRNA-seq) provides unprecedented insights into cellular heterogeneity, enabling detailed analysis of complex biological systems at single-cell resolution. However, the high dimensionality and technical noise…

Genomics · Quantitative Biology 2025-09-04 Hojjat Torabi Goudarzi , Maziyar Baran Pouyan

This paper proposes an innovative extension of Principal Component Analysis (PCA) that transcends the traditional assumption of data lying in Euclidean space, enabling its application to data on Riemannian manifolds. The primary challenge…

Machine Learning · Statistics 2025-06-03 Oldemar Rodríguez

Principal Component Analysis (PCA) is a fundamental tool for representation learning, but its global linear formulation fails to capture the structure of data supported on curved manifolds. In contrast, manifold learning methods model…

Machine Learning · Computer Science 2026-04-22 Alexandre L. M. Levada

Principal component analysis (PCA) is a widely used technique for data analysis and dimension reduction with numerous applications in science and engineering. However, the standard PCA suffers from the fact that the principal components…

Optimization and Control · Mathematics 2009-07-14 Zhaosong Lu , Yong Zhang

Principal component analysis (PCA) is a well-known linear dimension-reduction method that has been widely used in data analysis and modeling. It is an unsupervised learning technique that identifies a suitable linear subspace for the input…

Machine Learning · Statistics 2021-09-10 Shaojie Xu , Joel Vaughan , Jie Chen , Agus Sudjianto , Vijayan Nair

Sparse Principal Component Analysis (sPCA) is a cardinal technique for obtaining combinations of features, or principal components (PCs), that explain the variance of high-dimensional datasets in an interpretable manner. This involves…

Optimization and Control · Mathematics 2025-12-02 Ryan Cory-Wright , Jean Pauphilet

In this paper, we propose a new method to perform Sparse Kernel Principal Component Analysis (SKPCA) and also mathematically analyze the validity of SKPCA. We formulate SKPCA as a constrained optimization problem with elastic net…

Machine Learning · Computer Science 2018-09-17 Rudrajit Das , Aditya Golatkar , Suyash P. Awate

Principal Component Analysis (PCA) is a popular method for dimension reduction and has attracted an unfailing interest for decades. More recently, kernel PCA (KPCA) has emerged as an extension of PCA but, despite its use in practice, a…

Machine Learning · Computer Science 2023-01-25 Maxime Haddouche , Benjamin Guedj , John Shawe-Taylor

Principal component analysis (PCA) is one of the most widely used dimension reduction and multivariate statistical techniques. From a probabilistic perspective, PCA seeks a low-dimensional representation of data in the presence of…

Machine Learning · Computer Science 2021-01-06 Chihao Zhang , Kuo Gai , Shihua Zhang

Persistent homology is a central tool in topological data analysis, but its application to large and noisy datasets is often limited by computational cost and the presence of spurious topological features. Noise not only increases data size…

Computational Geometry · Computer Science 2026-04-01 Seonmi Choi , Semin Oh , Jeong Rye Park , Seung Yeop Yang

Robust tensor principal component analysis (RTPCA) aims to separate the low-rank and sparse components from multi-dimensional data, making it an essential technique in the signal processing and computer vision fields. Recently emerging…

Computer Vision and Pattern Recognition · Computer Science 2025-01-20 Lanlan Feng , Ce Zhu , Yipeng Liu , Saiprasad Ravishankar , Longxiu Huang