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The formation of polarized signaling domains on cell membranes is a fundamental example of biological pattern formation. While such patterns resemble structures from equilibrium phase separation, they are intrinsically non-equilibrium,…

Biological Physics · Physics 2025-12-10 Damiano Andreghetti , Alfredo Braunstein , Luca Dall'Asta , Andrea Gamba

Systems of independent active particles embedded into a fluctuating environment are relevant to many areas of soft-matter science. We use a minimal model of noninteracting spin-carrying Brownian particles in a Gaussian field and show that…

Soft Condensed Matter · Physics 2018-07-18 Ruben Zakine , Jean-Baptiste Fournier , Frédéric Van Wijland

The dynamics of an active walker in a harmonic potential is studied experimentally, numerically and theoretically. At odds with usual models of self-propelled particles, we identify two dynamical states for which the particle condensates at…

Soft Condensed Matter · Physics 2019-02-20 Olivier Dauchot , Vincent Démery

We study the role of active coupling on the transport properties of homogeneously charged macromolecules in an infinitely dilute solution. An enzyme becomes actively bound to a segment of the macromolecule, exerting an electrostatic force…

Soft Condensed Matter · Physics 2024-05-24 Tapas Singha , Siao-Fong Li , Murugappan Muthukumar

Off-lattice active Brownian particles form clusters and undergo phase separation even in the absence of attractions or velocity-alignment mechanisms. Arguments that explain this phenomenon appeal only to the ability of particles to move…

Statistical Mechanics · Physics 2018-05-28 Stephen Whitelam , Katherine Klymko , Dibyendu Mandal

Membraneless droplets or liquid condensates formed via liquid-liquid phase separation (LLPS) play a pivotal role in cell biology and hold potential for biomedical engineering. While membraneless droplets are often studied in the context of…

Soft Condensed Matter · Physics 2025-11-07 Chenxi Liu , Ding Cao , Siyu Liu , Yilin Wu

Active matter comprises self-driven units, such as bacteria and synthetic microswimmers, that can spontaneously form complex patterns and assemble into functional microdevices. These processes are possible thanks to the out-of-equilibrium…

Soft Condensed Matter · Physics 2021-11-17 Jens Grauer , Falko Schmidt , Jesus Pineda , Benjamin Midtvedt , Hartmut Löwen , Giovanni Volpe , Benno Liebchen

We study motility-induced phase separation~(MIPS) in active AB binary mixtures undergoing the chemical reaction $A \rightleftharpoons B$. Starting from the evolution equations for the density fields $\rho_i(\vec r, t)$ describing MIPS, we…

Soft Condensed Matter · Physics 2025-05-05 Sayantan Mondal , Prasenjit Das

Emulsions ripen with an average droplet size increasing in time. In chemically active emulsions, coarsening can be absent, leading to a non-equilibrium steady state with mono-disperse droplet sizes. By considering a minimal model for phase…

Soft Condensed Matter · Physics 2024-09-06 Jonathan Bauermann , Giacomo Bartolucci , Job Boekhoven , Frank Jülicher , Christoph A. Weber

Molecular dynamics computer simulations are used to investigate thedynamics of a binary mixture of charged (Yukawa) particles with a size-ratio of 1:5. We find that the system undergoes a phase transition where the large particles…

Disordered Systems and Neural Networks · Physics 2015-06-25 Norio Kikuchi , Juergen Horbach

One of the intrinsic characteristics of far-from-equilibrium systems is the nonrelaxational nature of the system dynamics, which leads to novel properties that cannot be understood and described by conventional pathways based on…

Soft Condensed Matter · Physics 2020-11-25 Zhi-Feng Huang , Andreas M. Menzel , Hartmut Löwen

Biomolecular condensates play a crucial role in the spatial organization of living matter. These membrane-less organelles, resulting from liquid-liquid phase separation, operate far from thermodynamic equilibrium, with their size and…

Soft Condensed Matter · Physics 2025-05-12 Jacques Fries , Roxanne Berthin , Marie Jardat , Pierre Illien , Vincent Dahirel

Cell crawling crucially depends on the collective dynamics of the acto-myosin cytoskeleton. However, it remains an open question to what extent cell polarization and persistent motion depend on continuous regulatory mechanisms and…

Biological Physics · Physics 2023-08-11 Fenna Stegemerten , Karin John , Uwe Thiele

Living systems routinely consume energy to achieve motility, often using intricate biomolecular machinery. In this work, we show that active droplets can sustain indefinite self-propulsion of a spherical colloid in an otherwise homogeneous,…

Soft Condensed Matter · Physics 2026-05-01 Benjamin Sorkin , Ned S. Wingreen

Active Brownian particles (ABPs) are termed out to be a successful way of modeling the moving microorganism on the substrate. In recent studies, it is shown that such organisms can sense the characteristics of the substrate. Motivated by…

Soft Condensed Matter · Physics 2023-10-31 Pawan Kumar Mishra , Ajeya Krishna , Shradha Mishra

To study the interplay of jamming, cluster formation, and motility-induced phase separation in the zero temperature limit in two dimensions, we consider a simple model system consisting of a bidisperse mixture of disks that are only subject…

Soft Condensed Matter · Physics 2023-06-16 Michael Schmiedeberg

We propose a method for describing a phase behavior of a system consisting of particles of two sorts. The interaction of each species is described by interaction potentials containing the repulsive and attractive components. Asymmetry is…

Statistical Mechanics · Physics 2020-06-19 M. P. Kozlovskii , O. A. Dobush

Active materials are capable of converting free energy into directional motion, giving rise to striking dynamical phenomena. Developing a general understanding of their structure in relation to the underlying non-equilibrium physics would…

Soft Condensed Matter · Physics 2018-10-17 Nitin Kumar , Rui Zhang , Juan J. de Pablo , Margaret L. Gardel

Active transport of biomolecular condensates and cell migration in collectives are fundamental to development, homeostasis, and processes such as cancer progression, wound healing, and infection response. Yet how these assemblies are…

Soft Condensed Matter · Physics 2025-10-24 Hossein Vahid , Jens-Uwe Sommer , Abhinav Sharma

Systems driven far from equilibrium may exhibit anomalous density fluctuations: active matter with orientational order display giant density fluctuations at large scale, while systems of interacting particles close to an absorbing phase…

Statistical Mechanics · Physics 2026-03-23 Sara Dal Cengio , Romain Mari , Eric Bertin