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Universal Multimodal Retrieval (UMR) aims to map different modalities (e.g., visual and textual) into a shared embedding space for multi-modal retrieval. Existing UMR methods can be broadly divided into two categories: early-fusion…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Juan Li , Chuanghao Ding , Xujie Zhang , Cam-Tu Nguyen

Functional groups and moieties are chemical descriptors of biomolecules that can be used to interpret their properties and functions, leading to the understanding of chemical or biological mechanisms. These chemical building blocks, or…

Biomolecules · Quantitative Biology 2021-11-08 Yasemin Yesiltepe , Ryan S. Renslow , Thomas O. Metz

Geometric representation-conditioned molecule generation provides an effective paradigm that decouples molecule representation modeling from structure generation. By decoupling molecule generation into two stages-first generating a…

Machine Learning · Computer Science 2026-05-11 Shaoheng Yan , Zian Li , Cai Zhou , Qiaojing Huang , Kai Liu , Muhan Zhang

Mimicry is a fundamental learning mechanism in humans, enabling individuals to learn new tasks by observing and imitating experts. However, applying this ability to robots presents significant challenges due to the inherent differences…

Robotics · Computer Science 2025-09-23 Hanjung Kim , Jaehyun Kang , Hyolim Kang , Meedeum Cho , Seon Joo Kim , Youngwoon Lee

The integration of deep learning in medical imaging has shown great promise for enhancing diagnostic, therapeutic, and research outcomes. However, applying universal models across multiple modalities remains challenging due to the inherent…

Image and Video Processing · Electrical Eng. & Systems 2024-12-30 Yixin Chen , Lin Gao , Yajuan Gao , Rui Wang , Jingge Lian , Xiangxi Meng , Yanhua Duan , Leiying Chai , Hongbin Han , Zhaoping Cheng , Zhaoheng Xie

Molecular representation learning is pivotal in predicting molecular properties and advancing drug design. Traditional methodologies, which predominantly rely on homogeneous graph encoding, are limited by their inability to integrate…

Machine Learning · Computer Science 2025-03-24 Mukun Chen , Jia Wu , Shirui Pan , Fu Lin , Bo Du , Xiuwen Gong , Wenbin Hu

The performance of hyperspectral unmixing may be constrained by low spatial resolution, which can be enhanced using super-resolution in a multitask learning way. However, integrating super-resolution and unmixing directly may suffer two…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Ruiying Li , Bin Pan , Qiaoying Qu , Xia Xu , Zhenwei Shi

In this work, we study various hybrid models of entropy-based and representativeness sampling techniques in the context of active learning in medical segmentation, in particular examining the role of UMAP (Uniform Manifold Approximation and…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 H. S. Tan , Kuancheng Wang , Rafe Mcbeth

Molecular property prediction (MPP) is a fundamental but challenging task in the computer-aided drug discovery process. More and more recent works employ different graph-based models for MPP, which have made considerable progress in…

Machine Learning · Computer Science 2023-12-29 Bangyi Zhao , Weixia Xu , Jihong Guan , Shuigeng Zhou

Universal Multimodal Retrieval (UMR) aims to enable search across various modalities using a unified model, where queries and candidates can consist of pure text, images, or a combination of both. Previous work has attempted to adopt…

Computation and Language · Computer Science 2025-04-02 Xin Zhang , Yanzhao Zhang , Wen Xie , Mingxin Li , Ziqi Dai , Dingkun Long , Pengjun Xie , Meishan Zhang , Wenjie Li , Min Zhang

Molecular property prediction refers to the task of labeling molecules with some biochemical properties, playing a pivotal role in the drug discovery and design process. Recently, with the advancement of machine learning, deep…

Molecular Networks · Quantitative Biology 2024-01-10 Zeyu Wang , Tianyi Jiang , Jinhuan Wang , Qi Xuan

Molecular Property Prediction (MPP) plays a pivotal role across diverse domains, spanning drug discovery, material science, and environmental chemistry. Fueled by the exponential growth of chemical data and the evolution of artificial…

Machine Learning · Computer Science 2024-08-23 Tanya Liyaqat , Tanvir Ahmad , Chandni Saxena

The classification of medical images is a pivotal aspect of disease diagnosis, often enhanced by deep learning techniques. However, traditional approaches typically focus on unimodal medical image data, neglecting the integration of diverse…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Jun-En Ding , Chien-Chin Hsu , Chi-Hsiang Chu , Shuqiang Wang , Feng Liu

SMILES, a crucial textual representation of molecular structures, has garnered significant attention as a foundation for pre-trained language models (LMs). However, most existing pre-trained SMILES LMs focus solely on the single-token level…

Machine Learning · Computer Science 2025-06-10 Kangjie Zheng , Siyue Liang , Junwei Yang , Bin Feng , Zequn Liu , Wei Ju , Zhiping Xiao , Ming Zhang

Molecule-and-text cross-modal representation learning has emerged as a promising direction for enhancing the quality of molecular representation, thereby improving performance in various scientific fields. However, most approaches employ a…

Quantitative Methods · Quantitative Biology 2025-03-04 Yikun Zhang , Geyan Ye , Chaohao Yuan , Bo Han , Long-Kai Huang , Jianhua Yao , Wei Liu , Yu Rong

Real-world multimodal data usually exhibit complex structural relationships beyond traditional one-to-one mappings like image-caption pairs. Entities across modalities interact in intricate ways, with images and text forming diverse…

Machine Learning · Computer Science 2025-10-21 Xuying Ning , Dongqi Fu , Tianxin Wei , Wujiang Xu , Jingrui He

Machine learning interatomic potentials (MLIPs) enables molecular dynamics (MD) simulations with ab initio accuracy and has been applied to various fields of physical science. However, the performance and transferability of MLIPs are…

Chemical Physics · Physics 2024-04-16 Taoyong Cui , Chenyu Tang , Mao Su , Shufei Zhang , Yuqiang Li , Lei Bai , Yuhan Dong , Xingao Gong , Wanli Ouyang

There has been a surge of recent interest in learning representations for graph-structured data. Graph representation learning methods have generally fallen into three main categories, based on the availability of labeled data. The first,…

Machine Learning · Computer Science 2022-04-13 Ines Chami , Sami Abu-El-Haija , Bryan Perozzi , Christopher Ré , Kevin Murphy

Representation learning for images has been advanced by recent progress in more complex neural models such as the Vision Transformers and new learning theories such as the structural causal models. However, these models mainly rely on the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Zitan Chen , Zhuang Qi , Xiao Cao , Xiangxian Li , Xiangxu Meng , Lei Meng

Multimodal large language models (MLLMs) have made impressive progress in many applications in recent years. However, chemical MLLMs that can handle cross-modal understanding and generation remain underexplored. To fill this gap, we propose…

Machine Learning · Computer Science 2025-08-05 Qian Tan , Dongzhan Zhou , Peng Xia , Wanhao Liu , Wanli Ouyang , Lei Bai , Yuqiang Li , Tianfan Fu