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The paper presents a numerical method for simulating flow and mechanics in fractured rock. The governing equations that couple the effects in the rock mass and in the fractures are obtained using the discrete fracture-matrix approach. The…

Numerical Analysis · Mathematics 2024-03-13 Jan Stebel , Jakub Kružík , David Horák , Jan Březina , Michal Béreš

Fast and realistic coupling of blood flow and vessel wall is of great importance to virtual surgery. In this paper, we propose a novel data-driven coupling method that formulates physics-based blood flow simulation as a regression problem,…

Graphics · Computer Science 2019-01-25 Xuejie Mai , Zhiyong Yuan , Qianqian Tong , Tianchen Yuan , Jianhui Zhao

Modelling interfacial dynamics with soluble surfactants in a multiphase system is a challenging task. Here, we consider the numerical approximation of a phase-field surfactant model with fluid flow. The nonlinearly coupled model consists of…

Computational Physics · Physics 2020-03-02 Guangpu Zhu , Jisheng Kou , Shuyu Sun , Jun Yao , Aifen Li

We develop two mathematical lumped parameter models for blood pressure distribution in the Fontan blood flow circulation: an ODE based spatially homogeneous model and a PDE based spatially inhomogeneous model. We present numerical…

Analysis of PDEs · Mathematics 2018-06-08 J. P. Keener , M. Chugunova , R. M. Taranets , M. G. Doyle

3D motion estimation from cine cardiac magnetic resonance (CMR) images is important for the assessment of cardiac function and diagnosis of cardiovascular diseases. Most of the previous methods focus on estimating pixel-/voxel-wise motion…

Image and Video Processing · Electrical Eng. & Systems 2022-09-07 Qingjie Meng , Wenjia Bai , Tianrui Liu , Declan P O'Regan , Daniel Rueckert

In this work we present a novel computational method for embedding arbitrary curved one-dimensional (1D) fibers into three-dimensional (3D) solid volumes, as e.g. in fiber-reinforced materials. The fibers are explicitly modeled with highly…

Computational Engineering, Finance, and Science · Computer Science 2023-08-25 Ivo Steinbrecher , Matthias Mayr , Maximilian J. Grill , Johannes Kremheller , Christoph Meier , Alexander Popp

4D Flow is an MRI sequence which allows acquisition of 3D images of the heart. The data is typically acquired volumetrically, so it must be reformatted to generate cardiac long axis and short axis views for diagnostic interpretation. These…

Computer Vision and Pattern Recognition · Computer Science 2017-11-07 Matthieu Le , Jesse Lieman-Sifry , Felix Lau , Sean Sall , Albert Hsiao , Daniel Golden

A Coupled Natural Circulation Loop (CNCL) consists of two Natural Circulation Loops (NCL) coupled thermally via a common heat exchanger. The transient modelling of such systems that have practical relevance has not been reported in the…

Fluid Dynamics · Physics 2018-04-27 Akhil Dass , Sateesh Gedupudi

We propose four novel mathematical models, describing the microscopic mechanisms of force generation in the cardiac muscle tissue, which are suitable for multiscale numerical simulations of cardiac electromechanics. Such models are based on…

Subcellular Processes · Quantitative Biology 2021-01-27 Francesco Regazzoni , Luca Dedè , Alfio Quarteroni

In this paper, we present a novel general framework grounded in the factor graph theory to solve kinematic and dynamic problems for multi-body systems. Although the motion of multi-body systems is considered to be a well-studied problem and…

Robotics · Computer Science 2021-07-27 José-Luis Blanco-Claraco , Antonio Leanza , Giulio Reina

Cardiac myocytes are the fundamental cells composing the heart muscle. The propagation of electric signals and chemical quantities through them is responsible for their nonlinear contraction and dilatation. In this study, a theoretical…

Soft Condensed Matter · Physics 2018-08-01 Pietro Lenarda , Alessio Gizzi , Marco Paggi

Morphology of cardiovascular tissue is influenced by the unsteady behavior of the blood flow and vice versa. Therefore, the pathogenesis of several cardiovascular diseases is directly affected by the blood-flow dynamics. Understanding flow…

Clinical guidance systems have been widely adopted to help medical staffs to avoid preventable medical errors such as delay in diagnosis, treatment or untended deviations from best practice guidelines. However, because patient condition…

Computers and Society · Computer Science 2016-10-24 Maryam Rahmaniheris , Yu Jiang , Lui Sha

Atrioventricular valve regurgitation is a significant cause of morbidity and mortality in patients with acquired and congenital cardiac valve disease. Image-derived computational modeling of atrioventricular valves has advanced…

Tissues and Organs · Quantitative Biology 2022-02-01 Wensi Wu , Stephen Ching , Steve A. Maas , Andras Lasso , Patricia Sabin , Jeffrey A. Weiss , Matthew A. Jolley

Dynamical systems are ubiquitous within science and engineering, from turbulent flow across aircraft wings to structural variability of proteins. Although some systems are well understood and simulated, scientific imaging often confronts…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Ali SaraerToosi , Renbo Tu , Kamyar Azizzadenesheli , Aviad Levis

Accurate assessment of intraventricular blood flow is essential for evaluating hemodynamic conditions in patients supported by Left Ventricular Assist Devices (LVADs). However, clinical imaging is either incompatible with LVADs or yields…

Accurate 3D representations of cardiac structures allow quantitative analysis of anatomy and function. In this work, we propose a method for reconstructing complete 3D cardiac shapes from segmentations of sparse planes in CT angiography…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Gino E. Jansen , Carolina Brás , R. Nils Planken , Mark J. Schuuring , Berto J. Bouma , Ivana Išgum

Hemodynamic parameters such as pressure and wall shear stress play an important role in diagnosis, prognosis, and treatment planning in cardiovascular diseases. These parameters can be accurately computed using computational fluid dynamics…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Patryk Rygiel , Julian Suk , Kak Khee Yeung , Christoph Brune , Jelmer M. Wolterink

Heliospheric plasmas require multi-scale and multi-physics considerations. On one hand, MHD codes are widely used for global simulations of the solar-terrestrial environments, but do not provide the most elaborate physical description of…

Computational Physics · Physics 2020-12-09 S. P. Moschou , I. V. Sokolov , O. Cohen , G. Toth , J. J. Drake , Z. Huang , C. Garraffo , J. D. Alvarado-Gómez , T. Gombosi

Sharing a common clock signal among the nodes is crucial for communication in synchronized networks. This work presents a heartbeat-based synchronization scheme for body-worn nodes. The principles of this coordination technique combined…

Networking and Internet Architecture · Computer Science 2020-05-13 Robin Benarrouch , Ali Moin , Flavien Solt , Antoine Frappé , Andreia Cathelin , Andreas Kaiser , Jan Rabaey
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