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We propose a novel adaptive design for clinical trials with time-to-event outcomes and covariates (which may consist of or include biomarkers). Our method is based on the expected entropy of the posterior distribution of a proportional…

Applications · Statistics 2016-03-29 James E. Barrett

Honeypots are designed to trap the attacker with the purpose of investigating its malicious behavior. Owing to the increasing variety and sophistication of cyber attacks, how to capture high-quality attack data has become a challenge in the…

Cryptography and Security · Computer Science 2024-02-12 Wenjun Fan , Zhihui Du , Max Smith-Creasey , David Fernández

Engineering collective adaptive systems (CAS) with learning capabilities is a challenging task due to their multi-dimensional and complex design space. Data-driven approaches for CAS design could introduce new insights enabling system…

Software Engineering · Computer Science 2020-08-11 Mirko D'Angelo , Sona Ghahremani , Simos Gerasimou , Johannes Grohmann , Ingrid Nunes , Sven Tomforde , Evangelos Pournaras

The interAdapt R package is designed to be used by statisticians and clinical investigators to plan randomized trials. It can be used to determine if certain adaptive designs offer tangible benefits compared to standard designs, in the…

Applications · Statistics 2014-06-19 Aaron Fisher , Harris Jaffee , Michael Rosenblum

Anomaly detection (AD) is a crucial machine learning task that aims to learn patterns from a set of normal training samples to identify abnormal samples in test data. Most existing AD studies assume that the training and test data are drawn…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Tri Cao , Jiawen Zhu , Guansong Pang

One of the major goals of incident response is to help an organization or a system owner to quickly identify and halt the attacks to minimize the damages (and financial loss) to the system being attacked. Typical incident responses rely…

Cryptography and Security · Computer Science 2025-02-05 Anthony Cheuk Tung Lai , Siu Ming Yiu , Ping Fan Ke , Alan Ho

This study designs an adaptive experiment for efficiently estimating average treatment effects (ATEs). In each round of our adaptive experiment, an experimenter sequentially samples an experimental unit, assigns a treatment, and observes…

Methodology · Statistics 2024-06-21 Masahiro Kato , Akihiro Oga , Wataru Komatsubara , Ryo Inokuchi

In the past few years, augmented reality (AR) and virtual reality (VR) technologies have experienced terrific improvements in both accessibility and hardware capabilities, encouraging the application of these devices across various domains.…

Human-Computer Interaction · Computer Science 2019-10-29 Marco Cavallo , Mishal Dholakia , Matous Havlena , Kenneth Ocheltree , Mark Podlaseck

The presence of interference, where the outcome of an individual may depend on the treatment assignment and behavior of neighboring nodes, can lead to biased causal effect estimation. Current approaches to network experiment design focus on…

Machine Learning · Computer Science 2024-05-22 Zahra Fatemi , Jean Pouget-Abadie , Elena Zheleva

Critical and sophisticated cyberattacks often take multitudes of reconnaissance, exploitations, and obfuscation techniques to penetrate through well protected enterprise networks. The discovery and detection of attacks, though needing…

Cryptography and Security · Computer Science 2021-03-26 Shanchieh Jay Yang , Ahmet Okutan , Gordon Werner , Shao-Hsuan Su , Ayush Goel , Nathan D. Cahill

We propose a novel statistical method for testing the results of anomaly detection (AD) under domain adaptation (DA), which we call CAD-DA -- controllable AD under DA. The distinct advantage of the CAD-DA lies in its ability to control the…

Machine Learning · Statistics 2023-10-24 Vo Nguyen Le Duy , Hsuan-Tien Lin , Ichiro Takeuchi

The last decade has seen an explosion in data sources available for the monitoring and prediction of environmental phenomena. While several inferential methods have been developed that make predictions on the underlying process by combining…

Methodology · Statistics 2023-03-06 Eun-Hye Yoo , Andrew Zammit-Mangion , Michael G. Chipeta

Randomized A/B tests within online learning platforms represent an exciting direction in learning sciences. With minimal assumptions, they allow causal effect estimation without confounding bias and exact statistical inference even in small…

Methodology · Statistics 2023-06-13 Adam C. Sales , Ethan B. Prihar , Johann A. Gagnon-Bartsch , Neil T. Heffernan

In drug discovery, highly automated high-throughput laboratories are used to screen a large number of compounds in search of effective drugs. These experiments are expensive, so one might hope to reduce their cost by only experimenting on a…

Machine Learning · Computer Science 2025-04-15 Ihor Neporozhnii , Julien Roy , Emmanuel Bengio , Jason Hartford

The integration of real-world data (RWD) and randomized controlled trials (RCT) is increasingly important for advancing causal inference in scientific research. This combination holds great promise for enhancing the efficiency of causal…

Methodology · Statistics 2024-07-02 Xi Lin , Jens Magelund Tarp , Robin J. Evans

Network interference has attracted significant attention in the field of causal inference, encapsulating various sociological behaviors where the treatment assigned to one individual within a network may affect the outcomes of others, such…

Machine Learning · Computer Science 2025-02-11 Zhiheng Zhang , Zichen Wang

Adaptive treatment assignment algorithms, such as bandit algorithms, are increasingly used in digital health intervention clinical trials. Frequently, the data collected from these trials is used to conduct causal inference and related data…

Methodology · Statistics 2025-10-30 Kelly W. Zhang , Nowell Closser , Anna L. Trella , Susan A. Murphy

Integrated IPD-AD analysis, which combines individual participant data (IPD) with aggregate data (AD), is increasingly recognized as an effective strategy for generating more reliable and generalizable inferences from heterogeneous studies.…

Methodology · Statistics 2026-03-03 Ming-Yueh Huang , Jing Qin , Chiung-Yu Huang

Real-World Data (RWD), with its large sample sizes and rich clinical detail, offers a compelling alternative to randomized controlled trials (RCTs) for studying treatment effects in diverse and complex patient populations. However, its…

Applications · Statistics 2026-05-26 Yifei Xu , Hwiyoung Lee , Zhenyao Ye , Yezhi Pan , Jingsong Zhou , Yun Yang , Chixiang Chen , Shuo Chen

We introduce a new task called Adaptable Error Detection (AED), which aims to identify behavior errors in few-shot imitation (FSI) policies based on visual observations in novel environments. The potential to cause serious damage to…

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