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Recent technical advancements allow cardiac MRI (CMR) examinations in the presence of so-called MRI conditional active cardiac implants at 3.0T. However, the artifact burden caused by susceptibility effects remain an obstacle. All…

Medical Physics · Physics 2022-04-05 Theresa Reiter , Ingo Weiss , Oliver M. Weber , Wolfgang R. Bauer

Transcranial focused ultrasound (tFUS) is an emerging form of non-surgical human neuromodulation that confers advantages over existing electro and electromagnetic technologies by providing a superior spatial resolution on the millimeter…

Neurons and Cognition · Quantitative Biology 2016-03-02 Leo Ai , Jerel K. Mueller , Andrea Grant , Yigitcan Eryaman , Wynn Legon

Medical ultrasound imaging is the most widespread real-time non-invasive imaging system and its formulation comprises signal transmission, signal reception, and image formation. Ultrasound signal transmission modelling has been formalized…

Numerical Analysis · Mathematics 2023-08-09 Chiara Razzetta , Valentina Candiani , Marco Crocco , Federico Benvenuto

Dynamic and precise measurement of cerebral blood flow velocity is crucial in neuroscience and the diagnosis of cerebrovascular diseases. Traditional color Doppler ultrasound can only measure the velocity component along the ultrasound…

Medical Physics · Physics 2025-04-25 Shaoyuan Yan , Yiming Ding , Guoao Ma , Yapeng Fu , Kailiang Xu , Dean Ta

In vivo measurement of the mechanical properties of thin-walled soft tissues (e.g., mitral valve, artery and bladder) and in situ mechanical characterization of thin-walled artificial soft biomaterials in service are of great challenge and…

Soft Condensed Matter · Physics 2020-09-02 Guo-Yang Li , Qiong He , Robert Mangan , Guoqiang Xu , Chi Mo , Jianwen Luo , Michel Destrade , Yanping Cao

BabelBrain is an open-source standalone graphic-user-interface application designed for studies of neuromodulation using transcranial focused ultrasound. It calculates the transmitted acoustic field in the brain tissue, taking into account…

Medical Physics · Physics 2023-05-10 Samuel Pichardo

Electroencephalogram (EEG) provides noninvasive measures of brain activity and is found to be valuable for diagnosis of some chronic disorders. Specifically, pre-treatment EEG signals in alpha and theta frequency bands have demonstrated…

Applications · Statistics 2023-05-24 Bin Yang , Xingche Guo , Ji Meng Loh , Qinxia Wang , Yuanjia Wang

Various intervention therapies ranging from pharmaceutical to hi-tech tailored solutions have been available to treat difficulty in falling asleep commonly caused by insomnia in modern life. However, current techniques largely remain…

Systems and Control · Electrical Eng. & Systems 2022-11-07 Anh Nguyen , Galen Pogoncheff , Ban Xuan Dong , Nam Bui , Hoang Truong , Nhat Pham , Linh Nguyen , Hoang Huu Nguyen , Sy Duong-Quy , Sangtae Ha , Tam Vu

Stiff and dense fibrin networks in chronic blood clots impede drug penetration and distribution into the clot core, limiting the efficacy of thrombolytic therapies. Acoustic cavitation of microbubbles is a promising strategy to enhance drug…

Soft Condensed Matter · Physics 2026-05-29 Aarushi Bhargava , Gaurav Gardi , Metin Sitti

Continuously measured arterial blood velocity can provide insight into physiological parameters and potential disease states. The efficient and effective description of the temporal profiles of arterial velocity is crucial for both clinical…

Quantitative Methods · Quantitative Biology 2024-02-16 Justen R Geddes , Amanda Randles

Ultrasound contrast agents have been recently utilized in therapeutical implementations for targeted delivery of pharmaceutical substances. Radial pulsations of the encapsulated microbubbles under the action of an ultrasound field are…

Soft Condensed Matter · Physics 2018-11-29 Farzan Ghalichi , Sohrab Behnia , Farshad Mottaghi , Mohammad Yahyavi

Traditionally, the occurrence of cavitation has been related to the ratio between flow velocity and pressure gradient in the case of hydrodynamic cavitation, or some combination of vapor pressure and surface tension. However, both…

Fluid Dynamics · Physics 2024-04-16 Gianmaria Viciconte , Paolo Guida , Tadd Truscott , William L. Roberts

Novel approaches for predicting the outcomes of blood-brain barrier (BBB) opening with focused ultrasound (FUS) and microbubbles are highly desired. This study aims to explore machine learning-based methods for reliably predicting the…

Medical Physics · Physics 2023-06-08 Wenjing Li , Chenchen Bing , Haixin Dai , Rajiv Chopra , Qian Wang , Bingbing Cheng

The local beat-to-beat local pulse pressure (PP) and blood pressure waveform of arteries, especially central arteries, are important indicators of the course of cardiovascular diseases (CVDs). Nevertheless, noninvasive measurement of them…

Signal Processing · Electrical Eng. & Systems 2023-05-30 Lirui Xu , Pang Wu , Pan Xia , Fanglin Geng , Peng Wang , Xianxiang Chen , Zhenfeng Li , Lidong Du , Shuping Liu , Li Li , Hongbo Chang , Zhen Fang

The mechanical properties of biological fluids can serve as early indicators of disease, offering valuable insights into complex physiological and pathological processes. However, the existing technologies can hardly support high throughput…

Optics · Physics 2025-09-18 Zhonghao Li , Zhihan Cai , Chaoyang Gong

Typically, an ultrasound flow imaging system employs the conventional delay and sum (DAS) beamformer due to its inherent low complexity. But the conventional DAS technique offers poor contrast, low imaging resolution, and limited…

Signal Processing · Electrical Eng. & Systems 2022-06-24 A. N. Madhavanunni , Mahesh Raveendranatha Panicker

Contrary to geometric acoustics-based simulations where the spatial information is available in a tangible form, it is not straightforward to auralize wave-based simulations. A variety of methods have been proposed that compute the ear…

Audio and Speech Processing · Electrical Eng. & Systems 2025-09-22 Jens Ahrens

Segmentation of medical images is a fundamental task with numerous applications. While MRI, CT, and PET modalities have significantly benefited from deep learning segmentation techniques, more recent modalities, like functional ultrasound…

Image and Video Processing · Electrical Eng. & Systems 2025-07-24 Hana Sebia , Thomas Guyet , Mickaël Pereira , Marco Valdebenito , Hugues Berry , Benjamin Vidal

Observing brain activity in real-world settings offers exciting possibilities like the support of physical health, mental well-being, and thought-controlled interaction modalities. The development of such applications is, however, strongly…

Human-Computer Interaction · Computer Science 2021-02-02 Michael Thomas Knierim , Christoph Berger , Pierluigi Reali

Ultrasound is an important imaging modality for biological systems. High-frequency ultrasound can also (e.g., via acoustical nonlinearities) be used to provide deeply penetrating and high-resolution imaging of vascular structure via…

Optics · Physics 2015-09-08 Ivan S. Maksymov , Andrew D. Greentree
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