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Ultrasound is a key technology in healthcare, and it is being explored for non-invasive, wearable, continuous monitoring of vital signs. However, its widespread adoption in this scenario is still hindered by the size, complexity, and power…

A variety of numerical methods exist for the study of deformable particles in dense suspensions. None of the standard tools, however, currently include volume-changing objects such as oscillating microbubbles in three-dimensional periodic…

Biological Physics · Physics 2017-08-14 Achim Guckenberger , Stephan Gekle

The blood-brain barrier plays a decisive role in protecting the brain from toxins and pathogens. The ability to analyze the BBB opening (OBBB) is crucial for the treatment of many brain diseases, but it is very difficult to noninvasively…

Ultrasound waves propagating in water or soft biological tissue are strongly reflected when encountering the skull, which limits the use of ultrasound-based techniques in transcranial imaging and therapeutic applications. Current knowledge…

Medical Physics · Physics 2017-06-07 Héctor Estrada , Johannes Rebling , Daniel Razansky

Minimally invasive interventions performed inside brain vessels with the synergistic use of microcatheters pushed over guidewires have revolutionized the way aneurysms, stroke, arteriovenous malformations, brain tumors and other…

Photoacoustic imaging (PAI), by combining high optical contrast with ultrasonic resolution, offers a promising noninvasive approach for dynamic monitoring of cerebral vasculature. However, transcranial PAI still faces significant challenges…

Ultrasound contrast imaging is a specialized imaging technique that applies microbubble contrast agents to traditional medical sonography, providing real-time visualization of blood flow and vessels. Gas-filled microbubbles are injected…

Analysis of PDEs · Mathematics 2024-12-17 Vanja Nikolić , Teresa Rauscher

Integrated photonic sensors can provide large scale, flexible detection schemes. Photonic crystal slabs (PCS) offer a miniaturized platform for wideband, sensitive ultrasound detection by exploiting the photoelastic effect in water.…

Applied Physics · Physics 2021-08-17 Eric Y. Zhu , Maria Charles-Herrera , Cory Rewcastle , Raanan Gad , Li Qian , Ofer Levi

Passive acoustic mapping (PAM) is a promising tool for monitoring acoustic cavitation activities in the applications of ultrasound therapy. Data-adaptive beamformers for PAM have better image quality compared to the time exposure acoustics…

Artificial Intelligence · Computer Science 2024-12-04 Yi Zeng , Jinwei Li , Hui Zhu , Shukuan Lu , Jianfeng Li , Xiran Cai

Active arterial mechanics, governed by vascular smooth muscle contraction, are critical to physiological regulation, cardiovascular disease progression, and clinical diagnosis. Although various in vivo methods have been developed to assess…

Medical Physics · Physics 2026-01-21 Yuxuan Jiang , Yanping Cao

Ultrasound, alone or in concert with circulating microbubble contrast agents, has emerged as a promising modality for therapy and imaging of brain diseases. While this has become possible due to advancements in aberration correction…

Signal Processing · Electrical Eng. & Systems 2020-01-08 Scott Schoen , Costas D. Arvanitis

We describe the use of monolithic, buckled-dome cavities as ultrasound sensors. Patterned delamination within a compressively stressed thin film stack produces high-finesse plano-concave optical resonators with sealed and empty cavity…

Instrumentation and Detectors · Physics 2022-09-07 G. J. Hornig , K. G. Scheuer , E. B. Dew , R. Zemp , R. G. DeCorby

Mapping blood microflows of the whole brain is crucial for early diagnosis of cerebral diseases. Ultrasound localization microscopy (ULM) was recently applied to map and quantify blood microflows in 2D in the brain of adult patients down to…

Medical Physics · Physics 2023-04-12 Hugues Favre , Mathieu Pernot , Mickael Tanter , Clément Papadacci

In this paper we present an electronic system to perform a non-invasive measurement of the blood pressure based on the oscillometric method, which does not suffer from the limitations of the well-known auscultatory one. Moreover the…

Medical Physics · Physics 2012-12-05 Roberto Marani , Anna Gina Perri

Synchronous imaging is used in dynamic space-domain vibration profile studies of capacitively driven, thin n+ doped poly-silicon microbridges oscillating at rf frequencies. Fast and high-resolution actuation profile measurements of…

Mesoscale and Nanoscale Physics · Physics 2015-06-03 Yoav Linzon , Daniel J. Joe , Slava Krylov , Bojan Ilic , Juraj Topolancik , Jeevak M. Parpia , Halrod G. Craighead

Ultrasound localization microscopy (ULM) refers to a promising medical imaging modality that systematically leverages the advantages of contrast-enhanced ultrasound (CEUS) to surpass the diffraction barrier and delineate the microvascular…

Image and Video Processing · Electrical Eng. & Systems 2022-09-22 Md Ashikuzzaman , Brandon Helfield , Hassan Rivaz

Mesoporous silica nanoparticles have been reported as suitable drug carriers, but their successful delivery to target tissues following systemic administration remains a challenge. In the present work, ultrasound-induced inertial cavitation…

Tissues and Organs · Quantitative Biology 2021-03-18 JL Paris , C Mannris , M Cabanas , R Calisle , M Manzano , M Vallet-Regi , CC Coussios

Cerebral arterial blood flow (CABF) can be investigated in few seconds without any synchronization by Real-Time phase contrast. Significant changes in CABF were found between expiration and inspiration during normal breathing of healthy…

Signal Processing · Electrical Eng. & Systems 2022-07-27 Pan Liu , Sidy Fall , Serge Metanbou , Olivier Balédent

This paper provides a mathematical analysis of ultrafast ultrasound imaging. This newly emerging modality for biomedical imaging uses plane waves instead of focused waves in order to achieve very high frame rates. We derive the point spread…

Numerical Analysis · Mathematics 2017-01-09 Giovanni S. Alberti , Habib Ammari , Francisco Romero , Timothée Wintz

Microbubbles excited by acoustic fields inside water oscillate, and generate acoustic radiation forces and drag-induced acoustic streaming. These forces can be harnessed in various biomedical applications such as targeted drug delivery and…

Fluid Dynamics · Physics 2022-05-26 Amit Dolev , Murat Kaynak , Mahmut Selman Sakar