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Mini-proteins and peptides manifest dynamic conformational fluctuation and involve mutual interconversion among metastable states. A robust mapping of the conformational landscape underlying mini-proteins and peptides often requires…

Chemical Physics · Physics 2021-09-29 Satyabrata Bandyopadhyay , Jagannath Mondal

In active matter, the lack of momentum conservation makes non-reciprocal interactions the rule rather than the exception. They lead to a rich set of emerging behaviors that are hard to account for and to predict starting from the…

Statistical Mechanics · Physics 2024-02-06 Alberto Dinelli , Jérémy O'Byrne , Agnese Curatolo , Yongfeng Zhao , Peter Sollich , Julien Tailleur

Cortical neurons emit seemingly erratic trains of action potentials or "spikes," and neural network dynamics emerge from the coordinated spiking activity within neural circuits. These rich dynamics manifest themselves in a variety of…

Neurons and Cognition · Quantitative Biology 2022-04-01 Braden A. W. Brinkman , Han Yan , Arianna Maffei , Il Memming Park , Alfredo Fontanini , Jin Wang , Giancarlo La Camera

Under certain conditions, the dynamics of coarse-grained models of solvated proteins can be described using a Markov state model, which tracks the evolution of populations of configurations. The transition rates among states that appear in…

Soft Condensed Matter · Physics 2022-09-26 Margarita Colberg , Jeremy Schofield

We use analytical techniques based on an expansion in the inverse system size to study the stochastic evolutionary dynamics of finite populations of players interacting in a repeated prisoner's dilemma game. We show that a mechanism of…

Populations and Evolution · Quantitative Biology 2012-04-20 Alex J. Bladon , Tobias Galla , Alan J. McKane

Continuous-time models have been developed to capture features of animal movement across temporal scales. In particular, one popular model is the continuous-time correlated random walk, in which the velocity of an animal is formulated as an…

Quantitative Methods · Quantitative Biology 2018-08-07 Théo Michelot , Paul G. Blackwell

The problem of determining dynamical models and trajectories that describe observed time-series data allowing for the understanding, prediction and possibly control of complex systems in nature is of a great interest in a wide variety of…

Data Analysis, Statistics and Probability · Physics 2007-05-23 V. N. Smelyanskiy , D. G. Luchinsky , M. Millons

We present a modelling approach for diffusion in a complex medium characterized by a random length scale. The resulting stochastic process shows subdiffusion with a behavior in qualitative agreement with single particle tracking experiments…

Statistical Mechanics · Physics 2016-12-14 Daniel Molina-García , Tuan Minh Pham , Paolo Paradisi , Carlo Manzo , Gianni Pagnini

Dormancy is an essential strategy for microorganisms to cope with environmental stress. However, global ecosystem models typically ignore microbial dormancy, resulting in major model uncertainties. To facilitate the consideration of…

Quantitative Methods · Quantitative Biology 2014-02-20 Gangsheng Wang , Melanie A. Mayes , Lianhong Gu , Christopher W. Schadt

The consistency across scales of a recently developed mathematical thermodynamic structure, between a continuous stochastic nonlinear dynamical system (diffusion process with Langevin or Fokker-Planck equations) and its emergent discrete,…

Statistical Mechanics · Physics 2015-10-28 Moises Santillan , Hong Qian

The concept of a `persistent worm' is introduced, representing the smallest possible length of a wormlike micelle, and modelled by a bead-spring chain with sticky beads at the ends. Persistent worms are allowed to combine with each other at…

Soft Condensed Matter · Physics 2025-10-14 Avishek Kumar , Rico F. Tabor , P. Sunthar , J. Ravi Prakash

To investigate interactions between parasite species in a host, a population of field voles was studied longitudinally, with presence or absence of six different parasites measured repeatedly. Although trapping sessions were regular, a…

Applications · Statistics 2013-01-29 Chris Sherlock , Tatiana Xifara , Sandra Telfer , Mike Begon

The paper is devoted to the relationship between the continuous Markovian description of Levy flights developed previously and their equivalent representation in terms of discrete steps of a wandering particle, a certain generalization of…

Statistical Mechanics · Physics 2015-06-04 Ihor Lubashevsky

Imagine you walk in a plane. You move by making a step of a certain length per time interval in a chosen direction. Repeating this process by randomly sampling step length and turning angle defines a two-dimensional random walk in what we…

Biological Physics · Physics 2026-01-05 Norberto Lucero Azuara , Rainer Klages

Cell cultures exhibit rich and complex behaviors driven by dynamic metabolic interactions among cells. In this work, we present a model that captures these interactions through a framework inspired by statistical mechanics. Using Monte…

Biological Physics · Physics 2025-09-25 A. R. Batista-Tomás , C. Díaz-Faloh , R. Mulet

Macroscopic dynamical descriptions of complex physical systems are crucial for understanding and controlling material behavior. With the growing availability of data and compute, machine learning has become a promising alternative to…

Computational Physics · Physics 2026-03-24 Mengyi Chen , Pengru Huang , Kostya S. Novoselov , Qianxiao Li

The temporal evolution of step-edge fluctuations under electromigration conditions is analysed using a continuum Langevin model. If the electromigration driving force acts in the step up/down direction, and step-edge diffusion is the…

Materials Science · Physics 2009-11-13 P. J. Rous , T. W. Bole

Individual Neurons in the nervous systems exploit various dynamics. To capture these dynamics for single neurons, we tune the parameters of an electrophysiological model of nerve cells, to fit experimental data obtained by calcium imaging.…

Quantitative Methods · Quantitative Biology 2017-11-07 Magdalena Fuchs , Manuel Zimmer , Radu Grosu , Ramin M. Hasani

This letter presents a novel approach to extract reliable dense and long-range motion trajectories of articulated human in a video sequence. Compared with existing approaches that emphasize temporal consistency of each tracked point, we…

Computer Vision and Pattern Recognition · Computer Science 2016-03-30 Yuanyuan Wu , Xiaohai He , Byeongkeun Kang , Haiying Song , Truong Q. Nguyen

The two dominant approaches for the analysis of species-habitat associations in animals have been shown to reach divergent conclusions. Models fitted from the viewpoint of an individual (step selection functions), once scaled up, do not…

Quantitative Methods · Quantitative Biology 2018-06-27 Théo Michelot , Paul G. Blackwell , Jason Matthiopoulos