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Window profiles of amino acids in protein sequences are taken as a description of the amino acid environment. The relative entropy or Kullback-Leibler distance derived from profiles is used as a measure of dissimilarity for comparison of…

Biological Physics · Physics 2009-11-07 Xin Liu , Li-mei Zhang , Shan Guan , Wei-Mou Zheng

We propose a new unsupervised anomaly detection method based on the sliced-Wasserstein distance for training data selection in machine learning approaches. Our filtering technique is interesting for decision-making pipelines deploying…

Machine Learning · Computer Science 2025-04-18 Julien Pallage , Antoine Lesage-Landry

While the existing stochastic control theory is well equipped to handle dynamical systems with stochastic uncertainties, a paradigm shift using distance measure based decision making is required for the effective further exploration of the…

Optimization and Control · Mathematics 2025-12-02 Venkatraman Renganathan , Sei Zhen Khong

We introduce the Continuous Edit Distance (CED), a geodesic and elastic distance for time-varying persistence diagrams (TVPDs). The CED extends edit-distance ideas to TVPDs by combining local substitution costs with penalized…

Computational Geometry · Computer Science 2025-12-16 Sebastien Tchitchek , Mohamed Kissi , Julien Tierny

We introduce a new weight and corresponding metric over finite extension fields for asymmetric error correction. The weight distinguishes between elements from the base field and the ones outside of it, which is motivated by asymmetric…

Information Theory · Computer Science 2024-06-26 Markus Grassl , Anna-Lena Horlemann , Violetta Weger

We consider the following model for sampling pairs of strings: $s_1$ is a uniformly random bitstring of length $n$, and $s_2$ is the bitstring arrived at by applying substitutions, insertions, and deletions to each bit of $s_1$ with some…

Data Structures and Algorithms · Computer Science 2020-07-08 Arun Ganesh , Aaron Sy

Frameshift mutations in protein-coding DNA sequences produce a drastic change in the resulting protein sequence, which prevents classic protein alignment methods from revealing the proteins' common origin. Moreover, when a large number of…

Quantitative Methods · Quantitative Biology 2011-01-18 Marta L. Gîrdea , Laurent Noé , Gregory Kucherov

Gene annotation has traditionally required direct comparison of DNA sequences between an unknown gene and a database of known ones using string comparison methods. However, these methods do not provide useful information when a gene does…

Machine Learning · Computer Science 2019-09-17 James K. Senter , Taylor M. Royalty , Andrew D. Steen , Amir Sadovnik

We address the problem of computing a textural loss based on the statistics extracted from the feature activations of a convolutional neural network optimized for object recognition (e.g. VGG-19). The underlying mathematical problem is the…

Computer Vision and Pattern Recognition · Computer Science 2021-03-12 Eric Heitz , Kenneth Vanhoey , Thomas Chambon , Laurent Belcour

In this article, we propose tree edit distance with variables, which is an extension of the tree edit distance to handle trees with variables and has a potential application to measuring the similarity between mathematical formulas,…

Data Structures and Algorithms · Computer Science 2021-05-12 Tatsuya Akutsu , Tomoya Mori , Naotoshi Nakamura , Satoshi Kozawa , Yuhei Ueno , Thomas N. Sato

Non-autoregressive neural machine translation (NAT) usually employs sequence-level knowledge distillation using autoregressive neural machine translation (AT) as its teacher model. However, a NAT model often outputs shorter sentences than…

Computation and Language · Computer Science 2021-07-30 Yui Oka , Katsuhito Sudoh , Satoshi Nakamura

Similarity search is an important problem in information retrieval. This similarity is based on a distance. Symbolic representation of time series has attracted many researchers recently, since it reduces the dimensionality of these high…

Information Retrieval · Computer Science 2010-06-18 Muhammad Marwan Muhammad Fuad , Pierre-François Marteau

Pairwise Euclidean distance calculation is a fundamental step in many machine learning and data analysis algorithms. In real-world applications, however, these distances are frequently distorted by heteroskedastic noise$\unicode{x2014}$a…

Machine Learning · Statistics 2025-09-12 Keyi Li , Yuval Kluger , Boris Landa

We establish a general framework to study the rate of convergence of a Euler type approximation scheme with decreasing time steps to the invariant measure, for a general class of stochastic systems. The error is measured in general…

Probability · Mathematics 2026-03-03 Aurélien Alfonsi , Vlad Bally , Arturo Kohatsu-Higa

The prevalent approach to sequence to sequence learning maps an input sequence to a variable length output sequence via recurrent neural networks. We introduce an architecture based entirely on convolutional neural networks. Compared to…

Computation and Language · Computer Science 2017-07-26 Jonas Gehring , Michael Auli , David Grangier , Denis Yarats , Yann N. Dauphin

Trajectory inference is a critical problem in single-cell transcriptomics, which aims to reconstruct the dynamic process underlying a population of cells from sequencing data. Of particular interest is the reconstruction of differentiation…

Genomics · Quantitative Biology 2026-04-06 Elodie Maignant , Tim Conrad , Christoph von Tycowicz

Attention mechanism in sequence-to-sequence models is designed to model the alignments between acoustic features and output tokens in speech recognition. However, attention weights produced by models trained end to end do not always…

Audio and Speech Processing · Electrical Eng. & Systems 2022-04-27 Gene-Ping Yang , Hao Tang

Many machine learning models use the manipulation of dimensions as a driving force to enable models to identify and learn important features in data. In the case of sequential data this manipulation usually happens on the token dimension…

Machine Learning · Computer Science 2023-10-24 Daniel Biermann , Fabrizio Palumbo , Morten Goodwin , Ole-Christoffer Granmo

Neural Machine Translation model is a sequence-to-sequence converter based on neural networks. Existing models use recurrent neural networks to construct both the encoder and decoder modules. In alternative research, the recurrent networks…

Computation and Language · Computer Science 2021-05-04 Ritam Mallick , Seba Susan , Vaibhaw Agrawal , Rizul Garg , Prateek Rawal

Sequence comparison is a prerequisite to virtually all comparative genomic analyses. It is often realised by sequence alignment techniques, which are computationally expensive. This has led to increased research into alignment-free…

Data Structures and Algorithms · Computer Science 2018-06-08 Panagiotis Charalampopoulos , Maxime Crochemore , Gabriele Fici , Robert Mercas , Solon P. Pissis
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