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Conventional and deep learning-based methods have shown great potential in the medical imaging domain, as means for deriving diagnostic, prognostic, and predictive biomarkers, and by contributing to precision medicine. However, these…

Anomalies are samples that significantly deviate from the rest of the data and their detection plays a major role in building machine learning models that can be reliably used in applications such as data-driven design and novelty…

Machine Learning · Statistics 2023-06-19 Amin Yousefpour , Mehdi Shishehbor , Zahra Zanjani Foumani , Ramin Bostanabad

Manifold learning is a hot research topic in the field of computer science and has many applications in the real world. A main drawback of manifold learning methods is, however, that there is no explicit mappings from the input data…

Computer Vision and Pattern Recognition · Computer Science 2010-01-18 Hong Qiao , Peng Zhang , Di Wang , Bo Zhang

Deep learning based image compression has recently witnessed exciting progress and in some cases even managed to surpass transform coding based approaches that have been established and refined over many decades. However, state-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2020-08-25 Leonhard Helminger , Abdelaziz Djelouah , Markus Gross , Christopher Schroers

Autoencoders, which consist of an encoder and a decoder, are widely used in machine learning for dimension reduction of high-dimensional data. The encoder embeds the input data manifold into a lower-dimensional latent space, while the…

Numerical Analysis · Mathematics 2024-03-29 Juliane Braunsmann , Marko Rajković , Martin Rumpf , Benedikt Wirth

System identification has greatly benefited from deep learning techniques, particularly for modeling complex, nonlinear dynamical systems with partially unknown physics where traditional approaches may not be feasible. However, deep…

Machine Learning · Computer Science 2025-04-17 Marco Forgione , Ankush Chakrabarty , Dario Piga , Matteo Rufolo , Alberto Bemporad

Generative modeling of symmetric densities has a range of applications in AI for science, from drug discovery to physics simulations. The existing generative modeling paradigm for invariant densities combines an invariant prior with an…

Machine Learning · Computer Science 2026-04-14 Kusha Sareen , Daniel Levy , Arnab Kumar Mondal , Sékou-Oumar Kaba , Tara Akhound-Sadegh , Siamak Ravanbakhsh

Normalizing Flows (NFs) are universal density estimators based on Neural Networks. However, this universality is limited: the density's support needs to be diffeomorphic to a Euclidean space. In this paper, we propose a novel method to…

Machine Learning · Computer Science 2022-02-02 Christian Horvat , Jean-Pascal Pfister

Canonical transformation plays a fundamental role in simplifying and solving classical Hamiltonian systems. We construct flexible and powerful canonical transformations as generative models using symplectic neural networks. The model…

Statistical Mechanics · Physics 2020-04-29 Shuo-Hui Li , Chen-Xiao Dong , Linfeng Zhang , Lei Wang

Neuronal activity is found to lie on low-dimensional manifolds embedded within the high-dimensional neuron space. Variants of principal component analysis are frequently employed to assess these manifolds. These methods are, however,…

Neurons and Cognition · Quantitative Biology 2025-06-19 Peter Bouss , Sandra Nestler , Kirsten Fischer , Claudia Merger , Alexandre René , Moritz Helias

Datasets such as images, text, or movies are embedded in high-dimensional spaces. However, in important cases such as images of objects, the statistical structure in the data constrains samples to a manifold of dramatically lower…

Machine Learning · Computer Science 2019-10-29 Stefano Recanatesi , Matthew Farrell , Madhu Advani , Timothy Moore , Guillaume Lajoie , Eric Shea-Brown

Manifold learning has been proven to be an effective method for capturing the implicitly intrinsic structure of non-Euclidean data, in which one of the primary challenges is how to maintain the distortion-free (isometry) of the data…

Machine Learning · Computer Science 2024-09-24 Zihao Chen , Wenyong Wang , Yu Xiang

Real world data often lie on low-dimensional Riemannian manifolds embedded in high-dimensional spaces. This motivates learning degenerate normalizing flows that map between the ambient space and a low-dimensional latent space. However, if…

Machine Learning · Computer Science 2026-04-14 Hanlin Yu , Søren Hauberg , Marcelo Hartmann , Arto Klami , Georgios Arvanitidis

The manifold hypothesis is a core mechanism behind the success of deep learning, so understanding the intrinsic manifold structure of image data is central to studying how neural networks learn from the data. Intrinsic dataset manifolds and…

Image and Video Processing · Electrical Eng. & Systems 2022-09-19 Nicholas Konz , Hanxue Gu , Haoyu Dong , Maciej A. Mazurowski

Deep generative models such as diffusion and flow matching are powerful machine learning tools capable of learning and sampling from high-dimensional distributions. They are particularly useful when the training data appears to be…

High Energy Physics - Phenomenology · Physics 2026-04-30 Zachary Bogorad , Ibrahim Elsharkawy , Yonatan Kahn , Andrew J. Larkoski , Noam Levi

Canonicalization is a widely used strategy in equivariant machine learning, enforcing symmetry in neural networks by mapping each input to a standard form. Yet, it often introduces discontinuities that can affect stability during training,…

Machine Learning · Computer Science 2026-04-17 Ya-Wei Eileen Lin , Ron Levie

A common belief in high-dimensional data analysis is that data are concentrated on a low-dimensional manifold. This motivates simultaneous dimension reduction and regression on manifolds. We provide an algorithm for learning gradients on…

Statistics Theory · Mathematics 2010-02-24 Sayan Mukherjee , Qiang Wu , Ding-Xuan Zhou

Likelihood-based, or explicit, deep generative models use neural networks to construct flexible high-dimensional densities. This formulation directly contradicts the manifold hypothesis, which states that observed data lies on a…

Machine Learning · Statistics 2022-11-30 Gabriel Loaiza-Ganem , Brendan Leigh Ross , Jesse C. Cresswell , Anthony L. Caterini

Continuous Normalizing Flows (CNFs) are a class of generative models that transform a prior distribution to a model distribution by solving an ordinary differential equation (ODE). We propose to train CNFs on manifolds by minimizing…

Manifold learning seeks a low dimensional representation that faithfully captures the essence of data. Current methods can successfully learn such representations, but do not provide a meaningful set of operations that are associated with…

Machine Learning · Computer Science 2019-08-21 David Eklund , Søren Hauberg