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Variable selection for optimal treatment regime in a clinical trial or an observational study is getting more attention. Most existing variable selection techniques focused on selecting variables that are important for prediction, therefore…

Methodology · Statistics 2014-05-22 Ailin Fan , Wenbin Lu , Rui Song

Both cluster randomized trials and quasi-experimental designs are used to evaluate the impact of health and social policies and interventions. Stepped-wedge cluster randomized trials randomize a staggered adoption approach, while recent…

Methodology · Statistics 2026-04-15 Haidong Lu , Gregg S. Gonsalves , Fan Li , Guanyu Tong , Lee Kennedy-Shaffer

Sequential recommender systems (SRS) could capture dynamic user preferences by modeling historical behaviors ordered in time. Despite effectiveness, focusing only on the \textit{collaborative signals} from behaviors does not fully grasp…

Information Retrieval · Computer Science 2024-09-20 Mingyue Cheng , Hao Zhang , Qi Liu , Fajie Yuan , Zhi Li , Zhenya Huang , Enhong Chen , Jun Zhou , Longfei Li

Sequential recommender systems (SRSs) aim to predict the subsequent items which may interest users via comprehensively modeling users' complex preference embedded in the sequence of user-item interactions. However, most of existing SRSs…

Information Retrieval · Computer Science 2024-10-31 Chengkai Huang , Shoujin Wang , Xianzhi Wang , Lina Yao

We developed a study design for rare disease clinical trials (RDTs) that efficiently evaluate treatments, promotes access to new treatments during treatment development, and optimizes healthcare resource utilization for future treatment…

Applications · Statistics 2016-07-04 Jian Yong , Sohaib H. Mohammad , Yan Yuan

Background: Mycobacterium Tuberculosis (TB) is an infectious bacterial disease presenting similar symptoms to pneumonia; therefore, differentiating between TB and pneumonia is challenging. Therefore, the main aim of this study is proposing…

Machine Learning · Computer Science 2020-09-07 Toktam Khatibi , Ali Farahani , Hossein Sarmadian

Online marketplaces frequently run pricing experiments in environments where users choose from a list of items. In these settings, items compete for users' limited attention and demand, creating interference among items within a list:…

Econometrics · Economics 2026-03-17 Mahyar Habibi , Zahra Khanalizadeh , Negar Ziaeian

Preference feedback, in the form of pairwise comparisons rather than scalar scores, has seen increasing use in applications such as human-, laboratory-, and expert-in-the-loop design, as well as scientific discovery. We propose a Thompson…

Machine Learning · Statistics 2026-04-29 Joseph Lazzaro , Davide Buffelli , Da-shan Shiu , Sattar Vakili

Given a sequence of sets, where each set has a timestamp and contains an arbitrary number of elements, temporal sets prediction aims to predict the elements in the subsequent set. Previous studies for temporal sets prediction mainly focus…

Machine Learning · Computer Science 2023-08-29 Le Yu , Zihang Liu , Leilei Sun , Bowen Du , Chuanren Liu , Weifeng Lv

Staggered treatment adoption arises in the evaluation of policy impact and implementation in many settings, including both randomized stepped-wedge trials and non-randomized quasi-experiments with panel data. In both settings, getting an…

Methodology · Statistics 2024-10-14 Lee Kennedy-Shaffer

Adaptive sample size re-estimation, early stopping, and trial re-design at interim analyses can reduce expected sample sizes in randomised trials. Cluster randomised trials, in which groups of participants are randomly allocated to…

Methodology · Statistics 2026-03-09 Samuel I. Watson , James Martin

Adaptive designs have been proposed for clinical trials in which the nuisance parameters or alternative of interest are unknown or likely to be misspecified before the trial. Whereas most previous works on adaptive designs and mid-course…

Methodology · Statistics 2011-05-18 Jay Bartroff , Tze Leung Lai

The Bayes factor, the data-based updating factor from prior to posterior odds, is a principled measure of relative evidence for two competing hypotheses. It is naturally suited to sequential data analysis in settings such as clinical trials…

Methodology · Statistics 2026-01-07 Samuel Pawel , Leonhard Held

The Win Ratio has gained significant traction in cardiovascular trials as a novel method for analyzing composite endpoints (Pocock and others, 2012). Compared with conventional approaches based on time to the first event, the Win Ratio…

Methodology · Statistics 2024-10-10 Baoshan Zhang , Yuan Wu

Most clinical prediction studies are developed from retrospective cohorts and reported as if all patient information were observed at once. In practice, clinicians face a more consequential question: \emph{when is there already enough…

Methodology · Statistics 2026-04-27 Hui-Mean Foo , Yuan-chin Ivan Chang

Triple difference designs have become increasingly popular in empirical economics. The advantage of a triple difference design is that, within a treatment group, it allows for another subgroup of the population -- potentially less impacted…

Econometrics · Economics 2025-06-04 Laura Caron

In this paper, we analyze the asymptotic properties of the Two-Stage (TS) estimator -- a simulation-based parameter estimation method that constructs estimators offline from synthetic data. While TS offers significant computational…

Systems and Control · Electrical Eng. & Systems 2025-08-26 Braghadeesh Lakshminarayanan , Cristian R. Rojas

Rejective sampling improves design and estimation efficiency of single-phase sampling when auxiliary information in a finite population is available. When such auxiliary information is unavailable, we propose to use two-phase rejective…

Methodology · Statistics 2025-01-14 Shu Yang , Peng Ding

Sepsis, characterized by a dysregulated immune response to infection, results in significant mortality, morbidity, and healthcare costs. The timely prediction of sepsis progression is crucial for reducing adverse outcomes through early…

Machine Learning · Computer Science 2026-01-01 Alireza Rafiei , Farshid Hajati , Alireza Rezaee , Amirhossien Panahi , Shahadat Uddin

This paper analyzes difference-in-differences designs with a continuous treatment. We show that treatment-on-the-treated-type parameters are identified under a parallel trends assumption analogous to the binary treatment case. However,…

Econometrics · Economics 2026-01-05 Brantly Callaway , Andrew Goodman-Bacon , Pedro H. C. Sant'Anna