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Vitrimers are a special class of polymers that undergo dynamic cross-linking under thermal stimuli. Their ability to exchange covalent bonds can be harnessed to mitigate damage in a composite or to achieve recyclable aerospace composites.…

Materials Science · Physics 2020-12-25 Gurmeet Singh , Veera Sundararaghavan

The ability to reason beyond established knowledge allows Organic Chemists to solve synthetic problems and to invent novel transformations. Here, we propose a model which mimics chemical reasoning and formalises reaction prediction as…

Artificial Intelligence · Computer Science 2017-12-27 Marwin H. S. Segler , Mark P. Waller

Protein language models (PLMs) have transformed sequence-based protein analysis, yet most applications rely only on final-layer embeddings, which may overlook biologically meaningful information encoded in earlier layers. We systematically…

Quantitative Methods · Quantitative Biology 2025-12-02 Ajit Kumar , IndraPrakash Jha

There has been rapidly growing demand of polymeric materials coming from different aspects of modern life because of the highly diverse physical and chemical properties of polymers. Polymer informatics is an interdisciplinary research field…

Soft Condensed Matter · Physics 2020-10-16 Stephen Wu , Hironao Yamada , Yoshihiro Hayashi , Massimiliano Zamengo , Ryo Yoshida

Data scarcity, bias, and experimental noise are all frequently encountered problems in the application of deep learning to chemical and material science disciplines. Transfer learning has proven effective in compensating for the lack in…

Chemical Physics · Physics 2021-03-16 Florence H. Vermeire , William H. Green

This study presents an innovative approach to predicting VCSEL emission characteristics using transformer neural networks. We demonstrate how to modify the transformer neural network for applications in physics. Our model achieved high…

Disordered Systems and Neural Networks · Physics 2025-09-17 Aleksei V. Belonovskii , Elizaveta I. Girshova , Erkki Lähderanta , Mikhail Kaliteevski

Synthesis prediction is a key accelerator for the rapid design of advanced materials. However, determining synthesis variables such as the choice of precursor materials is challenging for inorganic materials because the sequence of…

Materials Science · Physics 2023-06-13 Tanjin He , Haoyan Huo , Christopher J. Bartel , Zheren Wang , Kevin Cruse , Gerbrand Ceder

Polymers are attractive in applications like flexible electronics and thermal interface materials due to their mechanical compliance and processability. However, conventional polymers have low thermal conductivity (TC), limiting their heat…

Materials Science · Physics 2026-03-25 Yuhan Liu , Jiaxin Xu , Renzheng Zhang , Meng Jiang , Tengfei Luo

Retrosynthesis is essential for designing synthetic pathways for complex molecules and can be revolutionized by AI to automate and accelerate chemical synthesis planning for drug discovery and materials science. Here, we propose a…

Chemical Physics · Physics 2024-12-02 Seongeun Yun , Won Bo Lee

Communication scene recognition has been widely applied in practice, but using deep learning to address this problem faces challenges such as insufficient data and imbalanced data distribution. To address this, we designed a weighted loss…

Econometrics · Economics 2026-02-10 Jiasong Han , Yufei Feng , Xiaofeng Zhong

Molecules and materials are the foundation for the development of modern advanced industries such as energy storage systems and semiconductor devices. However, traditional trial-and-error methods or theoretical calculations are highly…

Transformers have achieved great success across a wide range of applications, yet the theoretical foundations underlying their success remain largely unexplored. To demystify the strong capacities of transformers applied to versatile…

Machine Learning · Computer Science 2026-03-25 Chenyang Zhang , Qingyue Zhao , Quanquan Gu , Yuan Cao

Plasticisers (PLs) are small additives commonly incorporated into polymer composites to enhance processability and improve mechanical properties. Their effectiveness depends heavily on their miscibility within the polymer melt, yet…

Soft Condensed Matter · Physics 2025-05-07 Lois Smith , Jessica Steele , Hossein Ali Karimi-Varzaneh , Paola Carbone

Polymerization is a fundamental chemical process enabling large-scale production of material components across modern industries. By transforming a monomer mixture into a cross-linked polymer network, polymerization induces changes in…

Soft Condensed Matter · Physics 2025-12-24 Xuanhe Li , Tal Cohen

It is important to develop sustainable processes in materials science and manufacturing that are environmentally friendly. AI can play a significant role in decision support here as evident from our earlier research leading to tools…

Artificial Intelligence · Computer Science 2023-03-27 Aparna S. Varde , Jianyu Liang

Recent advancements in computational chemistry have leveraged the power of trans-former-based language models, such as MoLFormer, pre-trained using a vast amount of simplified molecular-input line-entry system (SMILES) sequences, to…

Biomolecules · Quantitative Biology 2024-11-05 Tianhao Peng , Yuchen Li , Xuhong Li , Jiang Bian , Zeke Xie , Ning Sui , Shahid Mumtaz , Yanwu Xu , Linghe Kong , Haoyi Xiong

Deep learning models for anticipating the products of organic reactions have found many use cases, including validating retrosynthetic pathways and constraining synthesis-based molecular design tools. Despite compelling performance on…

Machine Learning · Computer Science 2025-01-14 John Bradshaw , Anji Zhang , Babak Mahjour , David E. Graff , Marwin H. S. Segler , Connor W. Coley

We study the ability to maintain information in a population of reacting polymers under the influence of decay, i.e., spontaneous breakdown of large polymers. At a certain decay rate, it becomes impossible to maintain a significant…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Wim Hordijk , Jose F. Fontanari

Current paper presents the first attempt of the digitalization of a complex polymerization process representing free-radical polymerization of vinyl monomers in the presence of small additives of stable radicals TEMPO and C60 fullerene.…

Chemical Physics · Physics 2023-12-25 Elena F. Sheka

Crystal graph neural networks are widely applicable in modeling experimentally synthesized compounds and hypothetical materials with unknown synthesizability. In contrast, structure-agnostic predictive algorithms allow exploring previously…

Materials Science · Physics 2025-11-06 Ivan Rubtsov , Ivan Dudakov , Yuri Kuratov , Vadim Korolev