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Coronary CT angiography (CCTA) has established its role as a non-invasive modality for the diagnosis of coronary artery disease (CAD). The CAD-Reporting and Data System (CAD-RADS) has been developed to standardize communication and aid in…

The standard non-invasive imaging technique used to assess the severity and extent of Coronary Artery Disease (CAD) is Coronary Computed Tomography Angiography (CCTA). However, manual grading of each patient's CCTA according to the…

With coronary artery disease (CAD) persisting to be one of the leading causes of death worldwide, interest in supporting physicians with algorithms to speed up and improve diagnosis is high. In clinical practice, the severeness of CAD is…

Heart disease is one of the most common diseases in middle-aged citizens. Among the vast number of heart diseases, the coronary artery disease (CAD) is considered as a common cardiovascular disease with a high death rate. The most popular…

Coronary artery disease (CAD) remains the leading cause of death globally, with computed tomography coronary angiography (CTCA) serving as a key diagnostic tool. However, coronary arterial analysis using CTCA, such as identifying…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Shisheng Zhang , Ramtin Gharleghi , Sonit Singh , Daniel Moses , Dona Adikari , Arcot Sowmya , Susann Beier

Coronary artery disease, the leading cause of cardiovascular mortality worldwide, can be assessed non-invasively by coronary computed tomography angiography (CCTA). Despite progress in automated CCTA analysis using deep learning, clinical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Jinkui Hao , Gorkem Durak , Halil Ertugrul Aktas , Ulas Bagci , Bradley D. Allen , Nilay S. Shah , Bo Zhou

Assessing coronary artery plaque segments in coronary CT angiography scans is an important task to improve patient management and clinical outcomes, as it can help to decide whether invasive investigation and treatment are necessary. In…

Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Rene Lisasi , Michele Esposito , Chen Zhao

Coronary artery disease (CAD) remains the leading cause of death globally and invasive coronary angiography (ICA) is considered the gold standard of anatomical imaging evaluation when CAD is suspected. However, risk evaluation based on ICA…

Functionally significant coronary artery disease (CAD) is caused by plaque buildup in the coronary arteries, potentially leading to narrowing of the arterial lumen, i.e. coronary stenosis, that significantly obstructs blood flow to the…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Nils Hampe , Sanne G. M. van Velzen , Jean-Paul Aben , Carlos Collet , Ivana Išgum

Coronary artery disease (CAD) remains a leading cause of mortality worldwide, requiring accurate segmentation and stenosis detection using Coronary Computed Tomography angiography (CCTA). Existing methods struggle with challenges such as…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Ni Yao , Xiangyu Liu , Danyang Sun , Chuang Han , Yanting Li , Jiaofen Nan , Chengyang Li , Fubao Zhu , Weihua Zhou , Chen Zhao

Coronary Artery Disease (CAD) remains a leading cause of morbidity and mortality worldwide. Early detection is critical to recover patient outcomes and decrease healthcare costs. In recent years, machine learning (ML) advancements have…

Artificial Intelligence · Computer Science 2026-03-10 Karan Kumar Singh , Nikita Gajbhiye , Gouri Sankar Mishra

Diagnostic investigation has an important role in risk stratification and clinical decision making of patients with suspected and documented Coronary Artery Disease (CAD). However, the majority of existing tools are primarily focused on the…

Coronary artery disease (CAD) remains a prevalent cardiovascular condition, posing significant health risks worldwide. This pathology, characterized by plaque accumulation in coronary artery walls, leads to myocardial ischemia and various…

Image and Video Processing · Electrical Eng. & Systems 2024-06-14 Xinyun Liu , Chen Zhao

Coronary artery disease (CAD) is the dominant cause of death and hospitalization across the globe. Atherosclerosis, an inflammatory condition that gradually narrows arteries and has potentially fatal effects, is the most frequent cause of…

Cardiovascular disease (CVD) accounts for about half of non-communicable diseases. Vessel stenosis in the coronary artery is considered to be the major risk of CVD. Computed tomography angiography (CTA) is one of the widely used noninvasive…

Image and Video Processing · Electrical Eng. & Systems 2023-10-18 An Zeng , Chunbiao Wu , Meiping Huang , Jian Zhuang , Shanshan Bi , Dan Pan , Najeeb Ullah , Kaleem Nawaz Khan , Tianchen Wang , Yiyu Shi , Xiaomeng Li , Guisen Lin , Xiaowei Xu

The accuracy of coronary artery disease (CAD) diagnosis is dependent on a variety of factors, including demographic, symptom, and medical examination, ECG, and echocardiography data, among others. In this context, artificial intelligence…

Artificial Intelligence · Computer Science 2023-08-30 Elham Nasarian , Danial Sharifrazi , Saman Mohsenirad , Kwok Tsui , Roohallah Alizadehsani

Coronary artery disease (CAD) is a leading cause of cardiovascular-related mortality, and accurate stenosis detection is crucial for effective clinical decision-making. Coronary angiography remains the gold standard for diagnosing CAD, but…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Baixiang Huang , Yu Luo , Guangyu Wei , Songyan He , Yushuang Shao , Xueying Zeng

Various types of atherosclerotic plaque and varying grades of stenosis could lead to different management of patients with coronary artery disease. Therefore, it is crucial to detect and classify the type of coronary artery plaque, as well…

Computer Vision and Pattern Recognition · Computer Science 2018-12-11 Majd Zreik , Robbert W. van Hamersvelt , Jelmer M. Wolterink , Tim Leiner , Max A. Viergever , Ivana Isgum

We assessed the benefit of combining stress cardiac CT perfusion (CCTP) myocardial blood flow (MBF) with coronary CT angiography (CCTA) using our innovative CCTP software. By combining CCTA and CCTP, one can uniquely identify a flow…

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