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With respect to spatial overlap, CNN-based segmentation of short axis cardiovascular magnetic resonance (CMR) images has achieved a level of performance consistent with inter observer variation. However, conventional training procedures…

Image and Video Processing · Electrical Eng. & Systems 2020-08-24 Nick Byrne , James R. Clough , Giovanni Montana , Andrew P. King

Outlier, or anomaly, detection is essential for optimal performance of machine learning methods and statistical predictive models. It is not just a technical step in a data cleaning process but a key topic in many fields such as fraudulent…

Machine Learning · Computer Science 2020-02-19 O. Ramos Terrades , A. Berenguel , D. Gil

Electrocardiogram (ECG) can be reliably used as a measure to monitor the functionality of the cardiovascular system. Recently, there has been a great attention towards accurate categorization of heartbeats. While there are many…

Computers and Society · Computer Science 2018-11-06 Mohammad Kachuee , Shayan Fazeli , Majid Sarrafzadeh

Cardiac motion estimation is an important diagnostic tool to detect heart diseases and it has been explored with modalities such as MRI and conventional ultrasound (US) sequences. US cardiac motion estimation still presents challenges…

Computer Vision and Pattern Recognition · Computer Science 2017-04-26 Angelica I. Aviles , Thomas Widlak , Alicia Casals , Maartje M. Nillesen , Habib Ammari

We propose a novel method for topological analysis of unweighted graphs which is based on \textit{persistent homology}. The proposed method maps the input graph to a complete weighted graph where the weighting function maps each edge to a…

Algebraic Topology · Mathematics 2020-07-31 Padraig Corcoran

The problem of (point) forecasting $ \textit{univariate} $ time series is considered. Most approaches, ranging from traditional statistical methods to recent learning-based techniques with neural networks, directly operate on raw time…

Machine Learning · Computer Science 2021-07-21 Sebastian Zeng , Florian Graf , Christoph Hofer , Roland Kwitt

We introduce a method for training neural networks to perform image or volume segmentation in which prior knowledge about the topology of the segmented object can be explicitly provided and then incorporated into the training process. By…

Computer Vision and Pattern Recognition · Computer Science 2020-09-21 James R. Clough , Nicholas Byrne , Ilkay Oksuz , Veronika A. Zimmer , Julia A. Schnabel , Andrew P. King

Optimal operation of distribution grid resources relies on accurate estimation of its state and topology. Practical estimation of such quantities is complicated by the limited presence of real-time meters. This paper discusses a theoretical…

Systems and Control · Computer Science 2020-01-06 Deepjyoti Deka , Michael Chertkov , Scott Backhaus

Complex prediction models such as deep learning are the output from fitting machine learning, neural networks, or AI models to a set of training data. These are now standard tools in science. A key challenge with the current generation of…

Machine Learning · Computer Science 2022-10-21 Meng Liu , Tamal K. Dey , David F. Gleich

Spatial transcriptomics studies are becoming increasingly large and commonplace, necessitating simultaneous analysis of a large number of spatially resolved variables. Correspondingly, a diverse range of methodologies have been proposed to…

Quantitative Methods · Quantitative Biology 2025-09-09 James Boyle , Gregory Hamm , Eleanor Williams , Robin JG Hartman , Magnus Soderburg , Ian Henry , Michael Casey

Background and purpose: Heart disease has been one of the most important causes of death in the last 10 years, so the use of classification methods to diagnose and predict heart disease is very important. If this disease is predicted before…

Machine Learning · Computer Science 2021-03-16 Jafar Abdollahi , Babak Nouri-Moghaddam

Objective: The Mapper algorithm is a qualitative method in topological data analysis that constructs graphs from point clouds by combining dimensionality reduction and clustering techniques. The aim of this study is to apply Mapper,…

Quantitative Methods · Quantitative Biology 2026-04-22 Aina Ferrà Marcús , Carles Casacuberta , Josep Vives , Joan Guich , Gerard Amorós-Figueras , Jose M. Guerra

Topological correctness is critical for segmentation of tubular structures, which pervade in biomedical images. Existing topological segmentation loss functions are primarily based on the persistent homology of the image. They match the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Bo Wen , Haochen Zhang , Dirk-Uwe G. Bartsch , William R. Freeman , Truong Q. Nguyen , Cheolhong An

Identifying the qualitative changes in time-series data provides insights into the dynamics associated with such data. Such qualitative changes can be detected through topological approaches, which first embed the data into a…

Data Analysis, Statistics and Probability · Physics 2019-03-27 Quoc Hoan Tran , Yoshihiko Hasegawa

Topological invariants, including the Chern numbers, can topologically classify parameterized Hamiltonians. We find that topological invariants can be properly defined and calculated even if the parameter space is discrete, which is done by…

Mesoscale and Nanoscale Physics · Physics 2023-11-21 Youjiang Xu , Walter Hofstetter

Topological accuracy in medical image segmentation is a highly important property for downstream applications such as network analysis and flow modeling in vessels or cell counting. Recently, significant methodological advancements have…

Image and Video Processing · Electrical Eng. & Systems 2024-10-10 Alexander H. Berger , Nico Stucki , Laurin Lux , Vincent Buergin , Suprosanna Shit , Anna Banaszak , Daniel Rueckert , Ulrich Bauer , Johannes C. Paetzold

A method evaluating the sensitivity of a given parameter to topological changes is proposed within the method of moments paradigm. The basis functions are used as degrees of freedom which, when compared to the classical pixeling technique,…

Computational Physics · Physics 2019-03-07 Miloslav Capek , Lukas Jelinek , Mats Gustafsson

In this paper, we propose a concept to design, track, and compare application-specific feature definitions expressed as sets of critical points. Our work has been inspired by the observation that in many applications a large variety of…

Machine Learning · Computer Science 2020-11-18 Wito Engelke , Talha Bin Masood , Jakob Beran , Rodrigo Caballero , Ingrid Hotz

Usually, clinicians assess the correct hemodynamic behavior and fetal well-being during the gestational age thanks to their professional expertise, with the support of some indices defined for Doppler fetal waveforms. Although this approach…

Feature attributions are post-training analysis methods that assess how various input features of a machine learning model contribute to an output prediction. Their interpretation is straightforward when features act independently, but it…

Machine Learning · Computer Science 2026-01-29 Kurt Butler , Guanchao Feng , Petar Djuric