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Depression is underdiagnosed in primary care, yet timely identification remains critical. Recorded clinical encounters, increasingly common with digital scribing technologies, present an opportunity to detect depression from naturalistic…

Computation and Language · Computer Science 2026-04-09 Feng Chen , Manas Bedmutha , Janice Sabin , Andrea Hartzler , Nadir Weibel , Trevor Cohen

Depression has proven to be a significant public health issue, profoundly affecting the psychological well-being of individuals. If it remains undiagnosed, depression can lead to severe health issues, which can manifest physically and even…

Human-Computer Interaction · Computer Science 2024-12-03 Chayan Tank , Sarthak Pol , Vinayak Katoch , Shaina Mehta , Avinash Anand , Rajiv Ratn Shah

Mental health disorders remain among the leading cause of disability worldwide, yet conditions such as depression, anxiety, and Post-Traumatic Stress Disorder (PTSD) are frequently underdiagnosed or misdiagnosed due to subjective…

Computation and Language · Computer Science 2025-10-17 Jianfeng Zhu , Julina Maharjan , Xinyu Li , Karin G. Coifman , Ruoming Jin

Background: Depression is a major public health concern, affecting an estimated five percent of the global population. Early and accurate diagnosis is essential to initiate effective treatment, yet recognition remains challenging in many…

Signal Processing · Electrical Eng. & Systems 2025-11-21 Jana Weber , Marcel Weber , Juan Miguel Lopez Alcaraz

Depression, as a typical mental disorder, has become a prevalent issue significantly impacting public health. However, the prevention and treatment of depression still face multiple challenges, including complex diagnostic procedures,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Yu Luo , Nan Huang , Sophie Yu , Hendry Xu , Jerry Wang , Colin Wang , Zhichao Liu , Chen Zeng

With the emergence of AI techniques for depression diagnosis, the conflict between high demand and limited supply for depression screening has been significantly alleviated. Among various modal data, audio-based depression diagnosis has…

Cryptography and Security · Computer Science 2026-03-27 Xintao Hu , Feng-Qi Cui

When using AI to detect signs of depressive disorder, AI models habitually draw preemptive conclusions. We theorize that using chain-of-thought (CoT) prompting to evaluate Patient Health Questionnaire-8 (PHQ-8) scores will improve the…

Computation and Language · Computer Science 2024-08-28 Elysia Shi , Adithri Manda , London Chowdhury , Runeema Arun , Kevin Zhu , Michael Lam

Depression is a common mental disorder which has been affecting millions of people around the world and becoming more severe with the arrival of COVID-19. Nevertheless proper diagnosis is not accessible in many regions due to a severe…

Speech is a noninvasive digital phenotype that can offer valuable insights into mental health conditions, but it is often treated as a single modality. In contrast, we propose the treatment of patient speech data as a trimodal multimedia…

Computation and Language · Computer Science 2025-07-24 Mai Ali , Christopher Lucasius , Tanmay P. Patel , Madison Aitken , Jacob Vorstman , Peter Szatmari , Marco Battaglia , Deepa Kundur

Existing depression screening predominantly relies on standardized questionnaires (e.g., PHQ-9, BDI), which suffer from high misdiagnosis rates (18-34% in clinical studies) due to their static, symptom-counting nature and susceptibility to…

Neurons and Cognition · Quantitative Biology 2025-04-24 Zhenguang Zhong , Zhixuan Wang

Perinatal depression (PND) affects 1 in 5 mothers, with 85% lacking support. Digital health tools offer early identification and prevention, potentially reducing PND risk by over 50% and improving engagement. Despite high interest, user…

Quantitative Methods · Quantitative Biology 2025-05-13 Rachel L. Wiley , Jim Schwoebel , Joel Shor , Bindu Chanagala , Matias Caccia , Adolfo M. García , Sheehan D. Fisher , Martin G. Frasch

Mental distress like depression and anxiety contribute to the largest proportion of the global burden of diseases. Automated diagnosis systems of such disorders, empowered by recent innovations in Artificial Intelligence, can pave the way…

Audio and Speech Processing · Electrical Eng. & Systems 2023-06-23 Mashrura Tasnim , Malikeh Ehghaghi , Brian Diep , Jekaterina Novikova

Traditional screening practices for anxiety and depression pose an impediment to monitoring and treating these conditions effectively. However, recent advances in NLP and speech modelling allow textual, acoustic, and hand-crafted…

Sound · Computer Science 2023-01-02 Brian Diep , Marija Stanojevic , Jekaterina Novikova

Depression has been the leading cause of mental-health illness worldwide. Major depressive disorder (MDD), is a common mental health disorder that affects both psychologically as well as physically which could lead to loss of lives. Due to…

Computer Vision and Pattern Recognition · Computer Science 2019-09-05 Anupama Ray , Siddharth Kumar , Rutvik Reddy , Prerana Mukherjee , Ritu Garg

Suicide remains a public health challenge, necessitating improved detection methods to facilitate timely intervention and treatment. This systematic review evaluates the role of Artificial Intelligence (AI) and Machine Learning (ML) in…

Audio and Speech Processing · Electrical Eng. & Systems 2025-10-29 Ambre Marie , Marine Garnier , Thomas Bertin , Laura Machart , Guillaume Dardenne , Gwenolé Quellec , Sofian Berrouiguet

This study investigates the utility of speech signals for AI-based depression screening across varied interaction scenarios, including psychiatric interviews, chatbot conversations, and text readings. Participants include depressed patients…

Sound · Computer Science 2024-06-13 Yangbin Chen , Chenyang Xu , Chunfeng Liang , Yanbao Tao , Chuan Shi

We developed computational models to predict the emergence of depression and Post-Traumatic Stress Disorder in Twitter users. Twitter data and details of depression history were collected from 204 individuals (105 depressed, 99 healthy). We…

Non-invasive methods for diagnosing mental health conditions, such as speech analysis, offer promising potential in modern medicine. Recent advancements in machine learning, particularly speech foundation models, have shown significant…

Audio and Speech Processing · Electrical Eng. & Systems 2024-10-01 Marc de Gennes , Adrien Lesage , Martin Denais , Xuan-Nga Cao , Simon Chang , Pierre Van Remoortere , Cyrille Dakhlia , Rachid Riad

Depression is the most common psychological disorder and is considered as a leading cause of disability and suicide worldwide. An automated system capable of detecting signs of depression in human speech can contribute to ensuring timely…

Sound · Computer Science 2023-02-21 Mashrura Tasnim , Jekaterina Novikova
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