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Related papers: MOFDiff: Coarse-grained Diffusion for Metal-Organi…

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Coarse-grained models are a core computational tool in theoretical chemistry and biophysics. A judicious choice of a coarse-grained model can yield physical insight by isolating the essential degrees of freedom that dictate the…

Statistical Mechanics · Physics 2023-04-12 Shriram Chennakesavalu , David J. Toomer , Grant M. Rotskoff

The ability to rapidly develop materials with desired properties has a transformative impact on a broad range of emerging technologies. In this work, we introduce a new framework based on the diffusion model, a recent generative machine…

Accurate prediction of physical properties is critical for discovering and designing novel materials. Machine learning technologies have attracted significant attention in the materials science community for their potential for large-scale…

Materials Science · Physics 2021-11-24 Boyu Zhang , Mushen Zhou , Jianzhong Wu , Fuchang Gao

Molecular generation with diffusion models has emerged as a promising direction for AI-driven drug discovery and materials science. While graph diffusion models have been widely adopted due to the discrete nature of 2D molecular graphs,…

Artificial Intelligence · Computer Science 2026-02-20 Hojung Jung , Rodrigo Hormazabal , Jaehyeong Jo , Youngrok Park , Kyunggeun Roh , Se-Young Yun , Sehui Han , Dae-Woong Jeong

Metal-organic framework (MOF) derived materials formed through high temperature processes show great potential as catalysts. However, understanding of structure-property relationships between the initial MOF and the resulting MOF-derived…

Materials Science · Physics 2026-01-26 Connor W. Edwards , Oliver M. Linder-Patton , Jack D. Evans

For a considerable time, researchers have focused on developing a method that establishes a deep connection between the generative diffusion model and mathematical physics. Despite previous efforts, progress has been limited to the pursuit…

Computer Vision and Pattern Recognition · Computer Science 2023-04-11 Weiyang Jin , Yongpei Zhu , Yuxi Peng

Metal-organic frameworks (MOFs) are a major target of machine-learning-based property prediction, yet most models assume that a single framework representation maps to a single property value. This assumption becomes problematic for…

Materials Science · Physics 2026-04-22 Seunghee Han , Jaewoong Lee , Jihan Kim

Motif scaffolding seeks to design scaffold structures for constructing proteins with functions derived from the desired motif, which is crucial for the design of vaccines and enzymes. Previous works approach the problem by inpainting or…

Biomolecules · Quantitative Biology 2024-06-06 Ke Liu , Weian Mao , Shuaike Shen , Xiaoran Jiao , Zheng Sun , Hao Chen , Chunhua Shen

Metal-organic frameworks (MOFs) can provide exceptional porosity for molecular guest encapsulation useful for emergent applications in sensing, gas storage, drug delivery and optoelectronics. Central to the realisation of such applications…

Soft Condensed Matter · Physics 2021-01-05 Annika F. Möslein , Mario Gutiérrez , Boiko Cohen , Jin-Chong Tan

With the advancement of AIGC, video frame interpolation (VFI) has become a crucial component in existing video generation frameworks, attracting widespread research interest. For the VFI task, the motion estimation between neighboring…

Computer Vision and Pattern Recognition · Computer Science 2024-08-05 Zhilin Huang , Yijie Yu , Ling Yang , Chujun Qin , Bing Zheng , Xiawu Zheng , Zikun Zhou , Yaowei Wang , Wenming Yang

Amorphous carbon (a-C) materials have diverse interesting and useful properties, but the understanding of their atomic-scale structures is still incomplete. Here, we report on extensive atomistic simulations of the deposition and growth of…

Materials Science · Physics 2020-11-05 Miguel A. Caro , Gábor Csányi , Tomi Laurila , Volker L. Deringer

Reconstructing materials in the real world has always been a difficult problem in computer graphics. Accurately reconstructing the material in the real world is critical in the field of realistic rendering. Traditionally, materials in…

Computer Vision and Pattern Recognition · Computer Science 2022-05-26 Zhiyao Luo , Hongnan Chen

Structure-based drug design (SBDD), which aims to generate molecules that can bind tightly to the target protein, is an essential problem in drug discovery, and previous approaches have achieved initial success. However, most existing…

Machine Learning · Computer Science 2024-04-04 Xinze Li , Penglei Wang , Tianfan Fu , Wenhao Gao , Chengtao Li , Leilei Shi , Junhong Liu

Multi-modality image fusion aims to combine different modalities to produce fused images that retain the complementary features of each modality, such as functional highlights and texture details. To leverage strong generative priors and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-24 Zixiang Zhao , Haowen Bai , Yuanzhi Zhu , Jiangshe Zhang , Shuang Xu , Yulun Zhang , Kai Zhang , Deyu Meng , Radu Timofte , Luc Van Gool

Nuclear Magnetic Resonance (NMR) spectroscopy is a central characterization method for molecular structure elucidation, yet interpreting NMR spectra to deduce molecular structures remains challenging due to the complexity of spectral data…

Chemical Physics · Physics 2025-07-15 Qingsong Yang , Binglan Wu , Xuwei Liu , Bo Chen , Wei Li , Gen Long , Xin Chen , Mingjun Xiao

Designing biological sequences that satisfy multiple, often conflicting, functional and biophysical criteria remains a central challenge in biomolecule engineering. While discrete flow matching models have recently shown promise for…

Machine Learning · Computer Science 2025-05-15 Tong Chen , Yinuo Zhang , Sophia Tang , Pranam Chatterjee

There has been a growing interest in developing diffusion-based Graph Neural Networks (GNNs), building on the connections between message passing mechanisms in GNNs and physical diffusion processes. However, existing methods suffer from…

Machine Learning · Computer Science 2025-08-18 Asela Hevapathige , Asiri Wijesinghe , Ahad N. Zehmakan

Large language models have demonstrated remarkable reasoning capabilities across diverse natural language tasks. However, comparable breakthroughs in scientific discovery are more limited, because understanding complex physical phenomena…

Machine Learning · Computer Science 2025-10-27 Jiyu Cui , Fang Wu , Haokai Zhao , Minggao Feng , Xenophon Evangelopoulos , Andrew I. Cooper , Yejin Choi

We investigate the existence of linear magnetism in the metal organic framework materials MOF-74-Fe, MOF-74-Co, and MOF-74-Ni, using first-principles density functional theory. MOF-74 displays regular quasi-linear chains of open-shell…

Materials Science · Physics 2013-03-08 Pieremanuele Canepa , Yves J. Chabal , T. Thonhauser

Simulations have acted as a cornerstone to understand MOF/polymer interface structure, however, no molecular-level simulation has yet been performed at the nanoparticle scale. In this work, a hybrid MARTINI/Force Matching (FM) force field…

Chemical Physics · Physics 2024-10-22 Cecilia M. S. Alvares , Rocio Semino