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Deep learning has shown significant potential in diagnosing neurodegenerative diseases from MRI data. However, most existing methods rely heavily on large volumes of labeled data and often yield representations that lack interpretability.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Fangqi Cheng , Yingying Zhao , Xiaochen Yang

Labeling medical images depends on professional knowledge, making it difficult to acquire large amount of annotated medical images with high quality in a short time. Thus, making good use of limited labeled samples in a small dataset to…

Computer Vision and Pattern Recognition · Computer Science 2022-10-04 Peng Jiang , Juan Liu , Lang Wang , Zhihui Ynag , Hongyu Dong , Jing Feng

Modeling dynamical systems is crucial for a wide range of tasks, but it remains challenging due to complex nonlinear dynamics, limited observations, or lack of prior knowledge. Recently, data-driven approaches such as Neural Ordinary…

Interpretability is a key issue when applying deep learning models to longitudinal brain MRIs. One way to address this issue is by visualizing the high-dimensional latent spaces generated by deep learning via self-organizing maps (SOM). SOM…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Jiahong Ouyang , Qingyu Zhao , Ehsan Adeli , Wei Peng , Greg Zaharchuk , Kilian M. Pohl

Ordinary differential equations (ODEs) can provide mechanistic models of temporally local changes of processes, where parameters are often informed by external knowledge. While ODEs are popular in systems modeling, they are less established…

Methodology · Statistics 2025-07-10 Maren Hackenberg , Astrid Pechmann , Clemens Kreutz , Janbernd Kirschner , Harald Binder

We propose a novel second-order optimization framework for training the emerging deep continuous-time models, specifically the Neural Ordinary Differential Equations (Neural ODEs). Since their training already involves expensive gradient…

Machine Learning · Computer Science 2021-11-09 Guan-Horng Liu , Tianrong Chen , Evangelos A. Theodorou

Current 3D semi-supervised segmentation methods face significant challenges such as limited consideration of contextual information and the inability to generate reliable pseudo-labels for effective unsupervised data use. To address these…

Computer Vision and Pattern Recognition · Computer Science 2023-11-22 Sanaz Karimijafarbigloo , Reza Azad , Yury Velichko , Ulas Bagci , Dorit Merhof

The success of self-supervised learning (SSL) has mostly been attributed to the availability of unlabeled yet large-scale datasets. However, in a specialized domain such as medical imaging which is a lot different from natural images, the…

Computer Vision and Pattern Recognition · Computer Science 2023-06-30 Soumitri Chattopadhyay , Soham Ganguly , Sreejit Chaudhury , Sayan Nag , Samiran Chattopadhyay

Automated medical image segmentation plays a key role in quantitative research and diagnostics. Convolutional neural networks based on the U-Net architecture are the state-of-the-art. A key disadvantage is the hard-coding of the receptive…

Image and Video Processing · Electrical Eng. & Systems 2019-10-24 Hans Pinckaers , Geert Litjens

Developing successful artificial intelligence systems in practice depends on both robust deep learning models and large, high-quality data. However, acquiring and labeling data can be prohibitively expensive and time-consuming in many…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Saba Dadsetan , Mohsen Hejrati , Shandong Wu , Somaye Hashemifar

Many successful methods developed for medical image analysis that are based on machine learning use supervised learning approaches, which often require large datasets annotated by experts to achieve high accuracy. However, medical data…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Banafshe Felfeliyan , Abhilash Hareendranathan , Gregor Kuntze , David Cornell , Nils D. Forkert , Jacob L. Jaremko , Janet L. Ronsky

Dynamic magnetic resonance imaging (MRI) plays an indispensable role in cardiac diagnosis. To enable fast imaging, the k-space data can be undersampled but the image reconstruction poses a great challenge of high-dimensional processing.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-03 Zi Wang , Min Xiao , Yirong Zhou , Chengyan Wang , Naiming Wu , Yi Li , Yiwen Gong , Shufu Chang , Yinyin Chen , Liuhong Zhu , Jianjun Zhou , Congbo Cai , He Wang , Di Guo , Guang Yang , Xiaobo Qu

Although self-supervised learning enables us to bootstrap the training by exploiting unlabeled data, the generic self-supervised methods for natural images do not sufficiently incorporate the context. For medical images, a desirable method…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Li Sun , Ke Yu , Kayhan Batmanghelich

Discontinuities and delayed terms are encountered in the governing equations of a large class of problems ranging from physics and engineering to medicine and economics. These systems cannot be properly modelled and simulated with standard…

Artificial Intelligence · Computer Science 2024-09-27 Thibault Monsel , Onofrio Semeraro , Lionel Mathelin , Guillaume Charpiat

I propose a novel framework that integrates stochastic differential equations (SDEs) with deep generative models to improve uncertainty quantification in machine learning applications involving structured and temporal data. This approach,…

Machine Learning · Statistics 2026-01-09 James Rice

We propose a novel Stochastic Differential Equation (SDE) framework to address the problem of learning uncertainty-aware representations for graph-structured data. While Graph Neural Ordinary Differential Equations (GNODEs) have shown…

Machine Learning · Computer Science 2025-09-15 Richard Bergna , Sergio Calvo-Ordoñez , Felix L. Opolka , Pietro Liò , Jose Miguel Hernandez-Lobato

Numerical simulation of ordinary differential equations (ODEs) can be challenging when the system exhibits high accelerations and rapidly changing dynamics. Under these conditions the ODE solver often needs to take very small time steps in…

Numerical Analysis · Mathematics 2026-05-11 Andrew Tagg , Andrew Frandsen , Andrew Ning

Computer-aided diagnosis via deep learning relies on large-scale annotated data sets, which can be costly when involving expert knowledge. Semi-supervised learning (SSL) mitigates this challenge by leveraging unlabeled data. One effective…

Machine Learning · Computer Science 2020-05-25 Prashnna Kumar Gyawali , Sandesh Ghimire , Pradeep Bajracharya , Zhiyuan Li , Linwei Wang

Is self-supervised deep learning (DL) for medical image analysis already a serious alternative to the de facto standard of end-to-end trained supervised DL? We tackle this question for medical image classification, with a particular focus…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Maximilian Nielsen , Laura Wenderoth , Thilo Sentker , René Werner

Unsupervised anomaly detection aims to build models to effectively detect unseen anomalies by only training on the normal data. Although previous reconstruction-based methods have made fruitful progress, their generalization ability is…

Machine Learning · Computer Science 2022-01-04 Yuxin Zhang , Jindong Wang , Yiqiang Chen , Han Yu , Tao Qin
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