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Medical diagnosis requires the effective synthesis of visual manifestations and clinical metadata. However, existing methods often treat metadata as isolated tags, failing to exploit the rich semantic knowledge embedded in clinical…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Yiqing Wang , Chunming He , Ming-Chen Lu , Mercy Pawar , Leslie Niziol , Maria Woodward , Sina Farsiu

The joint interpretation of multi-modal and multi-view fundus images is critical for retinopathy prevention, as different views can show the complete 3D eyeball field and different modalities can provide complementary lesion areas. Compared…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Yonghao Huang , Leiting Chen , Chuan Zhou

Widespread outreach programs using remote retinal imaging have proven to decrease the risk from diabetic retinopathy, the leading cause of blindness in the US. However, this process still requires manual verification of image quality and…

Computer Vision and Pattern Recognition · Computer Science 2016-12-14 Arjun Raj Rajanna , Kamelia Aryafar , Rajeev Ramchandran , Christye Sisson , Ali Shokoufandeh , Raymond Ptucha

Existing multi-modal learning methods on fundus and OCT images mostly require both modalities to be available and strictly paired for training and testing, which appears less practical in clinical scenarios. To expand the scope of clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Lehan Wang , Chongchong Qi , Chubin Ou , Lin An , Mei Jin , Xiangbin Kong , Xiaomeng Li

Diabetic Retinopathy (DR) is one of the microvascular complications of Diabetes Mellitus, which remains as one of the leading causes of blindness worldwide. Computational models based on Convolutional Neural Networks represent the state of…

Computer Vision and Pattern Recognition · Computer Science 2020-07-31 Santiago Toledo-Cortés , Melissa De La Pava , Oscar Perdómo , Fabio A. González

Self-supervised learning (SSL) has emerged as a powerful technique for improving the efficiency and effectiveness of deep learning models. Contrastive methods are a prominent family of SSL that extract similar representations of two…

Longitudinal NLP tasks require reasoning over temporally ordered text to detect persistence and change in human behavior and opinions. However, in-context learning with large language models struggles on tasks where models must integrate…

Computation and Language · Computer Science 2026-04-21 Iqra Ali , Talia Tseriotou , Mahmud Elahi Akhter , Yuxiang Zhou , Maria Liakata

Despite the revolutionary impact of AI and the development of locally trained algorithms, achieving widespread generalized learning from multi-modal data in medical AI remains a significant challenge. This gap hinders the practical…

Computer Vision and Pattern Recognition · Computer Science 2024-01-24 Fatema-E Jannat , Sina Gholami , Minhaj Nur Alam , Hamed Tabkhi

Convolutional neural networks (CNNs) have been successfully employed in recent years for the detection of radiological abnormalities in medical images such as plain x-rays. To date, most studies use CNNs on individual examinations in…

Machine Learning · Statistics 2018-10-11 Ruggiero Santeramo , Samuel Withey , Giovanni Montana

Due to the complexity of medical image acquisition and the difficulty of annotation, medical image datasets inevitably contain noise. Noisy data with wrong labels affects the robustness and generalization ability of deep neural networks.…

Computer Vision and Pattern Recognition · Computer Science 2025-04-18 Junlin Hou , Jilan Xu , Rui Feng , Hao Chen

Diabetes Mellitus (DM) can lead to significant microvasculature disruptions that eventually causes diabetic retinopathy (DR), or complications in the eye due to diabetes. If left unchecked, this disease can increase over time and eventually…

Image and Video Processing · Electrical Eng. & Systems 2022-08-10 Meysam Tavakoli , Patrick Kelley

Oculomics - the concept of predicting systemic diseases, such as cardiovascular disease and dementia, through retinal imaging - has advanced rapidly due to the data efficiency of transformer-based foundation models like RETFound.…

Machine Learning · Computer Science 2026-01-29 Hyunmin Kim , Yukun Zhou , Rahul A. Jonas , Lie Ju , Sunjin Hwang , Pearse A. Keane , Siegfried K. Wagner

3D reconstruction is a useful tool for surgical planning and guidance. However, the lack of available medical data stunts research and development in this field, as supervised deep learning methods for accurate disparity estimation rely…

Computer Vision and Pattern Recognition · Computer Science 2023-04-06 Alistair Weld , Joao Cartucho , Chi Xu , Joseph Davids , Stamatia Giannarou

Diabetic retinopathy (DR) is one of the leading causes of blindness in the working-age population of developed countries, caused by a side effect of diabetes that reduces the blood supply to the retina. Deep neural networks have been widely…

Computer Vision and Pattern Recognition · Computer Science 2022-08-05 Jose Miguel Arrieta Ramos , Oscar Perdómo , Fabio A. González

Disease progression modeling (DPM) using longitudinal data is a challenging task in machine learning for healthcare that can provide clinicians with better tools for diagnosis and monitoring of disease. Existing DPM algorithms neglect…

Computer Vision and Pattern Recognition · Computer Science 2018-08-17 Mostafa Mehdipour Ghazi , Mads Nielsen , Akshay Pai , M. Jorge Cardoso , Marc Modat , Sebastien Ourselin , Lauge Sørensen

The upsurge in pre-trained large models started by ChatGPT has swept across the entire deep learning community. Such powerful models demonstrate advanced generative ability and multimodal understanding capability, which quickly set new…

Computer Vision and Pattern Recognition · Computer Science 2025-02-28 Ning Ding , Yehui Tang , Zhongqian Fu , Chao Xu , Kai Han , Yunhe Wang

Diabetic retinopathy (DR) is a complication of diabetes, and one of the major causes of vision impairment in the global population. As the early-stage manifestation of DR is usually very mild and hard to detect, an accurate diagnosis via…

Computer Vision and Pattern Recognition · Computer Science 2022-12-14 Yuhan Zheng , Fuping Wu , Bartłomiej W. Papież

We propose a convolution neural network based algorithm for simultaneously diagnosing diabetic retinopathy and highlighting suspicious regions. Our contributions are two folds: 1) a network termed Zoom-in-Net which mimics the zoom-in…

Computer Vision and Pattern Recognition · Computer Science 2017-06-15 Zhe Wang , Yanxin Yin , Jianping Shi , Wei Fang , Hongsheng Li , Xiaogang Wang

Predicting whether a treatment leads to meaningful improvement is a central challenge in personalized medicine, particularly when disease progression manifests as subtle visual changes over time. While data-driven deep learning (DL) offers…

Image and Video Processing · Electrical Eng. & Systems 2025-11-21 Jana Armouti , Nikhil Madaan , Rohan Panda , Tom Fox , Laura Hutchins , Amita Krishnan , Ricardo Rodriguez , Bennett DeBoisblanc , Deva Ramanan , John Galeotti , Gautam Gare

Joint models initially dedicated to a single longitudinal marker and a single time-to-event need to be extended to account for the rich longitudinal data of cohort studies. Multiple causes of clinical progression are indeed usually…

Applications · Statistics 2016-01-26 Cécile Proust-Lima , Jean-François Dartigues , Hélène Jacqmin-Gadda