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The functions and elasticities of the cell are largely related to the structures of the cytoskeletons underlying the lipid bi-layer. Among various cell types, the Red Blood Cell (RBC) possesses a relatively simple cytoskeletal structure.…

Biological Physics · Physics 2016-01-20 Lipeng Lai , Xiaofeng Xu , Chwee Teck Lim , Jianshu Cao

Many biological processes are supported by special molecules, called motor proteins or molecular motors, that transport cellular cargoes along linear protein filaments and can reversibly associate to their tracks. Stimulated by these…

Statistical Mechanics · Physics 2021-11-17 Akriti Jindal , Anatoly B. Kolomeisky , Arvind Kumar Gupta

Despite decades of research on blood flow, an analogue of Navier-Stokes equations that accurately describe blood flow properties has not been established yet. The reason behind this is that the properties of blood flow seem \`a priori non…

Understanding how red blood cell (RBC) suspensions navigate porous materials is critical for for both fundamental physiology, such as maternal-fetal exchange in the placenta, and transformative biomedical applications, including rapid,…

Soft Condensed Matter · Physics 2025-09-03 Sampad Laha , Ananta Kumar Nayak , Alexander Farutin , Suman Chakraborty , Chaouqi Misbah

A simple model accounting for the ejection of heavy particles from the vortical structures of a turbulent flow is introduced. This model involves a space and time discretization of the dynamics and depends on only two parameters: the…

Chaotic Dynamics · Physics 2009-11-13 Jeremie Bec , Raphael Chetrite

Biological cells can actively tune their intracellular architecture according to their overall shape. Here we explore the rheological implication of such coupling in a minimal model of a dense cellular material where each cell exerts an…

Soft Condensed Matter · Physics 2022-04-13 Shao-Zhen Lin , Matthias Merkel , Jean-François Rupprecht

Percolation clusters are random fractals whose geometrical and transport properties can be characterized with the help of probability distribution functions. Using renormalized field theory, we determine the asymptotic form of various of…

Statistical Mechanics · Physics 2015-05-13 Hans-Karl Janssen , Olaf Stenull

We investigate the dynamics of the Red Blood Cell (RBC) in microfluidic channels under oscillatory flows. The simulations employ a hybrid continuum-particle approach, in which the cell membrane and cytosol fluid are modeled using…

Fluid Dynamics · Physics 2023-07-18 Lahcen Akerkouch , Trung Bao Le

Red Blood Cells (RBCs) are the simplest cell types with complex dynamical and viscoelastic phenomenology. While the mechanical rigidity and the flickering noise of RBCs have been extensively investigated, an accurate determination of the…

Biological Physics · Physics 2023-08-25 M. Gironella-Torrent , G. Bergamaschi , R. Sorkin , G. Wuite , F. Ritort

We present a numerical analysis of the rheology of a suspension of red blood cells (RBCs) in a wall-bounded shear flow. The flow is assumed as almost inertialess. The suspension of RBCs, modeled as biconcave capsules whose membrane follows…

Fluid Dynamics · Physics 2019-07-24 Naoki Takeishi , Marco E. Rosti , Yohsuke Imai , Shigeo Wada , Luca Brandt

The fast blood stream of animals is associated with large shear stresses. Consequently, blood cells have evolved a special morphology and a specific internal architecture allowing them to maintain their integrity over several weeks. For…

Subcellular Processes · Quantitative Biology 2022-10-12 Serge Dmitrieff , Adolfo Alsina , Aastha Mathur , François Nédélec

Two motions of oscillation and vacillating breathing (swing) of a red blood cell have been observed in bounded Poiseuille flows (Phys. Rev. E 85, 16307 (2012)). To understand such motions, we have studied the oscillating motion of a…

Fluid Dynamics · Physics 2013-04-19 Lingling Shi , Yao Yu , Tsorng-Whay Pan , Roland Glowinski

We present new results from a direct numerical simulation of a three dimensional homogeneous Rayleigh-Benard system (HRB), i.e. a convective cell with an imposed linear mean temperature profile along the vertical direction. We measure the…

Chaotic Dynamics · Physics 2007-05-23 L. Biferale , E. Calzavarini , F. Toschi , R. Tripiccione

We use a minimal model for a dense suspension undergoing thickening and thinning to investigate microstructural changes in 2d simulations. Our simulations show that in steady flow the contact network contains distinct building blocks which…

Soft Condensed Matter · Physics 2026-04-15 William C. J. Buchholtz , Daniel L. Blair , Jeffrey S. Urbach , H. A. Vinutha , Emanuela Del Gado

Osmotic conditions play an important role in the cell properties of human red blood cells (RBCs), which are crucial for the pathological analysis of some blood diseases such as malaria. Over the past decades, numerous efforts have mainly…

The distribution of Red Blood Cells in a confined channel flow is inhomogeneous and shows a marked depletion near the walls due to a competition between migration away from the walls and shear-induced diffusion resulting from interactions…

Biological Physics · Physics 2015-06-15 Xavier Grandchamp , Gwennou Coupier , Aparna Srivastav , Christophe Minetti , Thomas Podgorski

The deformability of human red blood cells (RBCs), which comprise almost 99% of the cells in whole blood, is largely related not only to pathophysiological blood flow but also to the levels of intracellular compounds. Therefore, statistical…

How can repulsive and attractive forces, acting on a conservative system, create stable traveling patterns or branching instabilities? We have proposed to study this question in the framework of the hyperbolic Keller-Segel system with…

Pattern Formation and Solitons · Physics 2015-05-20 Benoit Perthame , Christian Schmeiser , Min Tang , Nicolas Vauchelet

Dynamical polydispersity in single-particle properties, for example a fluctuating particle size, shape, charge density, etc., is intrinsic to responsive colloids (RCs), such as biomacromolecules or microgels, but is typically not resolved…

Soft Condensed Matter · Physics 2021-05-26 Upayan Baul , Joachim Dzubiella

We study the rheology of a soft particulate system where the inter-particle interactions are weakly attractive. Using extensive molecular dynamics simulations, we scan across a wide range of packing fractions ($\phi$), attraction strengths…

Soft Condensed Matter · Physics 2016-11-30 Ehsan Irani , Pinaki Chaudhuri , Claus Heussinger