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Establishing precise control over the shape and the interactions of the microscopic building blocks is essential for design of macroscopic soft materials with novel structural, optical and mechanical properties. Here, we demonstrate robust…

Biological materials are self-assembled with near-atomic precision in living cells, whereas synthetic 3D structures generally lack such precision and controllability. Recently, DNA nanotechnology, especially DNA origami technology, has been…

DNA nanotechnology allows for the realization of complex nanoarchitectures in which the spatial arrangements of different constituents and most functions can be enabled by DNA. When optically active components are integrated in such…

Biological Physics · Physics 2021-05-10 Pengfei Zhan , Steffen Both , Thomas Weiss , Na Liu

The controlled assembly of solid-state spins with nanoscale spatial precision is an outstanding challenge for quantum technology. Here, we combine DNA-based patterning with nitrogen-vacancy (NV) ensemble quantum sensors in diamond to form…

The specificity and simplicity of the Watson-Crick base pair interactions make DNA one of the most versatile construction materials for creating nanoscale structures and devices. Among several DNA-based approaches, the DNA origami technique…

Optics · Physics 2021-05-04 Anton Kuzyk , Ralf Jungmann , Guillermo P. Acuna , Na Liu

We report spin-selective tunneling of electrons along natural and artificial double-stranded DNA (dsDNA) sandwiched by nonmagnetic leads. The results reveal that the spin polarization strongly depends on the dsDNA sequence and is dominated…

Soft Condensed Matter · Physics 2015-06-11 Ai-Min Guo , Qing-feng Sun

Spin filtering is an essential operation in spintronics that allows creation and detection of spin polarized carriers. Transition metal ferromagnets are used as spin filters in most cases, though their spin filtering efficiency is only…

Mesoscale and Nanoscale Physics · Physics 2017-10-27 K. M. Alam , Sandipan Pramanik

We use the oxDNA coarse-grained model to provide a detailed characterization of the fundamental structural properties of DNA origamis, focussing on archetypal 2D and 3D origamis. The model reproduces well the characteristic pattern of helix…

Soft Condensed Matter · Physics 2019-02-21 Benedict E. K. Snodin , John S. Schreck , Flavio Romano , Ard A. Louis , Jonathan P. K. Doye

Recent advances enable the creation of nanoscale building blocks with complex geometries and interaction specificities for self-assembly. This nearly boundless design space necessitates design principles for defining the mutual interactions…

Soft Condensed Matter · Physics 2024-03-29 Daichi Hayakawa , Thomas E. Videbæk , Gregory M. Grason , W. Benjamin Rogers

We present a modular DNA origami design approach to address the challenges of assembling geometrically complex nanoscale structures, including those with nonuniform Gaussian curvature. This approach features a core structure that completely…

DNA origami is a powerful method to achieve nanoscale folded structures. Despite rapid improvements in folding and purification methods, DNA origami objects are still often produced in small quantities and studied at single molecule scale.…

Engineering shape and interactions of nanoscopic building blocks allows for the assembly of rationally designed macroscopic three-dimensional (3D) materials with spatial accuracy inaccessible to top-down fabrication methods. Owing to its…

Coordinating functional parts to operate in concert is essential for machinery. In gear trains, meshed gears are compactly interlocked, working together to impose rotation or translation. In photosynthetic systems, a variety of biological…

Biological Physics · Physics 2021-05-10 Pengfei Zhan , Maximilian J. Urban , Steffen Both , Xiaoyang Duan , Anton Kuzyk , Thomas Weiss , Na Liu

DNA origami is a widely used method to construct nanostructures by self-assembling designed DNA strands. These structures are often used as "pegboards" for templated assembly of proteins, gold nanoparticles, aptamers, and other molecules,…

Soft Condensed Matter · Physics 2024-11-05 Matthew Sample , Hao Liu , Thong Diep , Michael Matthies , Petr Šulc

Surface plasmon resonances generated in metallic nanostructures can be utilized to tailor electromagnetic fields. The precise spatial arrangement of such structures can result in surprising optical properties that are not found in any…

Intercalation of drug molecules into synthetic DNA nanostructures formed through self-assembled origami has been postulated as a valuable future method for targeted drug delivery. This is due to the excellent biocompatibility of synthetic…

An ideal nanofabrication method should allow the organization of nanoparticles and molecules with nanometric positional precision, stoichiometric control and well-defined orientation. The DNA origami technique has evolved into a highly…

The functionalization of atomically-thin transition metal dichalcogenides (TMDs) with organic molecules is a promising approach for realizing nanoscale optoelectronic devices with tailored functionalities, such as quantum light generation…

We show how coarse-grained modelling combined with umbrella sampling using distance-based order parameters can be applied to compute the free-energy landscapes associated with mechanical deformations of large DNA nanostructures. We…

Soft Condensed Matter · Physics 2022-02-21 Chak Kui Wong , Chuyan Tang , John S. Schreck , Jonathan P. K. Doye

DNA origami consists of a long scaffold strand and short staple strands that self-assemble into a target 2D or 3D shape. It is a widely used construct in nucleic acid nanotechnology, offering a cost-effective way to design and create…

Soft Condensed Matter · Physics 2024-09-23 Sarah Haggenmueller , Michael Matthies , Matthew Sample , Petr Šulc
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