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Although generative models hold promise for discovering molecules with optimized desired properties, they often fail to suggest synthesizable molecules that improve upon the known molecules seen in training. We find that a key limitation is…

Machine Learning · Computer Science 2025-01-07 Evan R. Antoniuk , Peggy Li , Nathan Keilbart , Stephen Weitzner , Bhavya Kailkhura , Anna M. Hiszpanski

In this work, we show how a genetic algorithm (GA) can be used to find step-by-step solutions to introductory physics problems. Our perspective is that the underlying task for this is one of finding a sequence of equations that will lead to…

Neural and Evolutionary Computing · Computer Science 2025-08-18 Tom Bensky , Justin Kopcinski

Most current work in NLP utilizes deep learning, which requires a lot of training data and computational power. This paper investigates the strengths of Genetic Algorithms (GAs) for extractive summarization, as we hypothesized that GAs…

Computation and Language · Computer Science 2022-01-11 William Chen , Kensal Ramos , Kalyan Naidu Mullaguri , Annie S. Wu

Genetic algorithms are heuristic optimization techniques inspired by Darwinian evolution, which are characterized by successfully finding robust solutions for optimization problems. Here, we propose a subroutine-based quantum genetic…

Quantum Physics · Physics 2024-06-07 Rubén Ibarrondo , Giancarlo Gatti , Mikel Sanz

Software Testing is a process to identify the quality and reliability of software, which can be achieved through the help of proper test data. However, doing this manually is a difficult task due to the presence of number of predicate nodes…

Software Engineering · Computer Science 2014-01-22 Yeresime Suresh , Santanu Ku. Rath

We recently reported that the simple genetic algorithm (SGA) is capable of performing a remarkable form of sublinear computation which has a straightforward connection with the general problem of interacting attributes in data-mining. In…

Neural and Evolutionary Computing · Computer Science 2009-05-18 Keki M. Burjorjee

When a Genetic Algorithm (GA), or a stochastic algorithm in general, is employed in a statistical problem, the obtained result is affected by both variability due to sampling, that refers to the fact that only a sample is observed, and…

Computation · Statistics 2019-03-07 Manuel Rizzo , Francesco Battaglia

In recent years the scientific community has devoted much effort in the development of deep learning models for the generation of new molecules with desirable properties (i.e. drugs). This has produced many proposals in literature. However,…

Machine Learning · Computer Science 2020-08-24 Davide Rigoni , Nicolò Navarin , Alessandro Sperduti

Graph neural networks (GNNs) have emerged as powerful tools to accurately predict materials and molecular properties in computational discovery pipelines. In this article, we exploit the invertible nature of these neural networks to…

Machine Learning · Computer Science 2024-06-06 Félix Therrien , Edward H. Sargent , Oleksandr Voznyy

Generative methods (Gen-AI) are reviewed with a particular goal of solving tasks in machine learning and Bayesian inference. Generative models require one to simulate a large training dataset and to use deep neural networks to solve a…

Computation · Statistics 2025-05-20 Maria Nareklishvili , Nick Polson , Vadim Sokolov

There are a number of ways to procedurally generate interesting three-dimensional shapes, and a method where a cellular neural network is combined with a mesh growth algorithm is presented here. The aim is to create a shape from a genetic…

Neural and Evolutionary Computing · Computer Science 2016-03-30 Hugo Martay

Universal induction relies on some general search procedure that is doomed to be inefficient. One possibility to achieve both generality and efficiency is to specialize this procedure w.r.t. any given narrow task. However, complete…

Neural and Evolutionary Computing · Computer Science 2018-09-13 Alexey Potapov , Sergey Rodionov

The integration of artificial intelligence (AI) in early-stage drug discovery offers unprecedented opportunities for exploring chemical space and accelerating hit-to-lead optimization. However, docking optimization in generative approaches…

Quantitative Methods · Quantitative Biology 2025-10-03 Ekaterina Podplutova , Anastasia Vepreva , Olga A. Konovalova , Vladimir Vinogradov , Dmitrii O. Shkil , Andrei Dmitrenko

Application of Genetic Algorithm (GA) for determination of parameters of an analytical representation of diatomic molecule potential is presented. GA can be used for finding potential characteristics of an electronic energy state which can…

Chemical Physics · Physics 2020-05-12 Tomasz Urbanczyk , Jaroslaw Koperski

We introduce genetic algorithms as a means to analyze supernovae type Ia data and extract model-independent constraints on the evolution of the Dark Energy equation of state. Specifically, we will give a brief introduction to the genetic…

Cosmology and Nongalactic Astrophysics · Physics 2010-01-15 C. Bogdanos , Savvas Nesseris

A while ago, the ideas of evolutionary biology inspired computer scientists to develop a thriving nowadays field of evolutionary computation (EC), in general, and genetic algorithms (GA), in particular. At the same time, the directed…

Quantitative Methods · Quantitative Biology 2019-12-09 Alexander Spirov , Ekaterina Myasnikova

Music Generation (MG) is an interesting research topic that links the art of music and Artificial Intelligence (AI). The goal is to train an artificial composer to generate infinite, fresh, and pleasurable musical pieces. Music has…

Sound · Computer Science 2020-04-10 Majid Farzaneh , Rahil Mahdian Toroghi

Convolutional Neural Networks (CNNs) have gained a significant attraction in the recent years due to their increasing real-world applications. Their performance is highly dependent to the network structure and the selected optimization…

Neural and Evolutionary Computing · Computer Science 2019-10-01 Parsa Esfahanian , Mohammad Akhavan

One important feature of complex systems are problem domains that have many local minima and substructure. Biological systems manage these local minima by switching between different subsystems depending on their environmental or…

Neural and Evolutionary Computing · Computer Science 2022-08-25 Ankit Grover , Vaishali Yadav , Bradly Alicea

Multiprocessor task scheduling is an important and computationally difficult problem. This paper proposes a comparison study of genetic algorithm and list scheduling algorithm. Both algorithms are naturally parallelizable but have heavy…

Performance · Computer Science 2010-02-08 S. R. Vijayalakshmi , G. Padmavathi