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Meta-analytic methods tend to take all-or-nothing approaches to study-level heterogeneity, assuming all studies are heterogeneous or homogeneous, leading to inefficiency and/or bias in estimation and inference. In this paper, we develop a…

Methodology · Statistics 2026-03-12 Elizabeth M. Davis , Emily C. Hector

We consider the problem of statistical inference for a class of partially-observed diffusion processes, with discretely-observed data and finite-dimensional parameters. We construct unbiased estimators of the score function, i.e. the…

Methodology · Statistics 2021-05-12 Jeremy Heng , Jeremie Houssineau , Ajay Jasra

Multivariate density estimation is a popular technique in statistics with wide applications including regression models allowing for heteroskedasticity in conditional variances. The estimation problems become more challenging when…

Methodology · Statistics 2018-08-15 Zhen Li , Lili Wu , Weilian Zhou , Sujit Ghosh

Wide conditions are provided to guarantee asymptotic unbiasedness and L^2-consistency of the introduced estimates of the Kullback-Leibler divergence for probability measures in R^d having densities w.r.t. the Lebesgue measure. These…

Statistics Theory · Mathematics 2019-07-02 Alexander Bulinski , Denis Dimitrov

Switching dynamical systems provide a powerful, interpretable modeling framework for inference in time-series data in, e.g., the natural sciences or engineering applications. Since many areas, such as biology or discrete-event systems, are…

Machine Learning · Computer Science 2021-09-30 Lukas Köhs , Bastian Alt , Heinz Koeppl

Many applications in image-guided surgery and therapy require fast and reliable non-linear, multi-modal image registration. Recently proposed unsupervised deep learning-based registration methods have demonstrated superior performance…

Image and Video Processing · Electrical Eng. & Systems 2022-10-07 Gerard Snaauw , Michele Sasdelli , Gabriel Maicas , Stephan Lau , Johan Verjans , Mark Jenkinson , Gustavo Carneiro

Information theoretic quantities play an important role in various settings in machine learning, including causality testing, structure inference in graphical models, time-series problems, feature selection as well as in providing privacy…

Information Theory · Computer Science 2018-10-30 Arman Rahimzamani , Himanshu Asnani , Pramod Viswanath , Sreeram Kannan

We correct claims about lower bounds on mutual information (MI) between real-valued random variables made in A. Kraskov {\it et al.}, Phys. Rev. E {\bf 69}, 066138 (2004). We show that non-trivial lower bounds on MI in terms of linear…

Data Analysis, Statistics and Probability · Physics 2013-05-29 David V. Foster , Peter Grassberger

Mutual information has many applications in image alignment and matching, mainly due to its ability to measure the statistical dependence between two images, even if the two images are from different modalities (e.g., CT and MRI). It…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Jiecheng Liao , Junhao Lu , Jeff Ji , Jiacheng He

The problem of how to properly quantify redundant information is an open question that has been the subject of much recent research. Redundant information refers to information about a target variable S that is common to two or more…

Information Theory · Computer Science 2017-07-14 Robin A. A. Ince

Phase-amplitude coupling is a phenomenon observed in several neurological processes, where the phase of one signal modulates the amplitude of another signal with a distinct frequency. The modulation index (MI) is a common technique used to…

Methodology · Statistics 2023-10-10 Marco Antonio Pinto-Orellana , Hernando Ombao , Beth Lopour

Efficient information processing is crucial for both living organisms and engineered systems. The mutual information rate, a core concept of information theory, quantifies the amount of information shared between the trajectories of input…

Molecular Networks · Quantitative Biology 2025-09-01 Manuel Reinhardt , Age J. Tjalma , Anne-Lena Moor , Christoph Zechner , Pieter Rein ten Wolde

We are assisting at a growing interest in the development of learning architectures with application to digital communication systems. Herein, we consider the detection/decoding problem. We aim at developing an optimal neural architecture…

Information Theory · Computer Science 2022-09-02 Andrea M. Tonello , Nunzio A. Letizia

Variational mutual information (MI) estimators are widely used in unsupervised representation learning methods such as contrastive predictive coding (CPC). A lower bound on MI can be obtained from a multi-class classification problem, where…

Machine Learning · Computer Science 2020-12-04 Jiaming Song , Stefano Ermon

Current meta-learning approaches focus on learning functional representations of relationships between variables, i.e. on estimating conditional expectations in regression. In many applications, however, we are faced with conditional…

Machine Learning · Statistics 2021-02-25 Jean-Francois Ton , Lucian Chan , Yee Whye Teh , Dino Sejdinovic

An important feature of kernel mean embeddings (KME) is that the rate of convergence of the empirical KME to the true distribution KME can be bounded independently of the dimension of the space, properties of the distribution and smoothness…

Statistics Theory · Mathematics 2025-04-17 Geoffrey Wolfer , Pierre Alquier

Cross-modality data translation has attracted great interest in image computing. Deep generative models (\textit{e.g.}, GANs) show performance improvement in tackling those problems. Nevertheless, as a fundamental challenge in image…

Computer Vision and Pattern Recognition · Computer Science 2023-02-01 Zihao Wang , Yingyu Yang , Maxime Sermesant , Hervé Delingette , Ona Wu

We introduce a framework for generating highly multimodal datasets with explicitly calculable mutual information (MI) between modalities. This enables the construction of benchmark datasets that provide a novel testbed for systematic…

Machine Learning · Statistics 2026-02-26 Raheem Karim Hashmani , Garrett W. Merz , Helen Qu , Mariel Pettee , Kyle Cranmer

Estimating the mutual information from samples from a joint distribution is a challenging problem in both science and engineering. In this work, we realize a variational bound that generalizes both discriminative and generative approaches.…

Machine Learning · Statistics 2023-06-05 Marco Federici , David Ruhe , Patrick Forré

The mutual information between two jointly distributed random variables $X$ and $Y$ is a functional of the joint distribution $P_{XY},$ which is sometimes difficult to handle or estimate. A coarser description of the statistical behavior of…

Information Theory · Computer Science 2016-11-17 Yanjun Han , Or Ordentlich , Ofer Shayevitz