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Background: Lung cancer was known as primary cancers and the survival rate of cancer is about 15%. Early detection of lung cancer is the leading factor in survival rate. All symptoms (features) of lung cancer do not appear until the cancer…

Artificial Intelligence · Computer Science 2016-01-26 Mitra Montazeri , Mahdieh Soleymani Baghshah , Ahmad Enhesari

Accurate lung tumor segmentation is crucial for improving diagnosis, treatment planning, and patient outcomes in oncology. However, the complexity of tumor morphology, size, and location poses significant challenges for automated…

Image and Video Processing · Electrical Eng. & Systems 2026-02-16 Elena Mulero Ayllón , Massimiliano Mantegna , Linlin Shen , Paolo Soda , Valerio Guarrasi , Matteo Tortora

Accurate classification of lung diseases from chest CT scans plays an important role in computer-aided diagnosis systems. However, medical imaging datasets often suffer from severe class imbalance, which may significantly degrade the…

Image and Video Processing · Electrical Eng. & Systems 2026-03-18 Kejin Lu , Jianfa Bai , Qingqiu Li , Runtian Yuan , Jilan Xu , Junlin Hou , Yuejie Zhang , Rui Feng

Recurrence and metastasis have been regarded as two of the greatest obstacles for curing cancer. Cancer stem cell (CSC) have been found. They contribute to cancer development with the distinct feature of recurrence and resistance to the…

Cell Behavior · Quantitative Biology 2018-08-20 Chong Yu , Qiong Liu , Cong Chen , Jin Wang

Objectives: To develop and validate a deep learning (DL)-based primary tumor biopsy signature for predicting axillary lymph node (ALN) metastasis preoperatively in early breast cancer (EBC) patients with clinically negative ALN. Methods: A…

Image and Video Processing · Electrical Eng. & Systems 2022-06-09 Feng Xu , Chuang Zhu , Wenqi Tang , Ying Wang , Yu Zhang , Jie Li , Hongchuan Jiang , Zhongyue Shi , Jun Liu , Mulan Jin

One of the deadliest cancers, lung cancer necessitates an early and precise diagnosis. Because patients have a better chance of recovering, early identification of lung cancer is crucial. This review looks at how to diagnose lung cancer…

Machine Learning · Computer Science 2025-01-22 Omid Shahriyar , Babak Nuri Moghaddam , Davoud Yousefi , Abbas Mirzaei , Farnaz Hoseini

Clinical management of cancer has continuously evolved for several decades. Biochemical, molecular and genomics approaches have brought and still bring numerous insights into cancerous diseases. It is now accepted that some phenomena,…

Primary tumors often emerge within genetically altered fields of premalignant cells that appear histologically normal but have a high chance of progression to malignancy. Clinical observations have suggested that these premalignant fields…

Populations and Evolution · Quantitative Biology 2013-09-06 Jasmine Foo , Kevin Leder , Marc Ryser

With the development of computer technology, various models have emerged in artificial intelligence. The transformer model has been applied to the field of computer vision (CV) after its success in natural language processing (NLP).…

Computer Vision and Pattern Recognition · Computer Science 2022-07-05 Ruina Sun , Yuexin Pang

Infectious diseases remain one of the major causes of human mortality and suffering. Mathematical models have been established as an important tool for capturing the features that drive the spread of the disease, predicting the progression…

Cancer is a leading cause of death in many countries. An early diagnosis of cancer based on biomedical imaging ensures effective treatment and a better prognosis. However, biomedical imaging presents challenges to both clinical institutions…

Computer Vision and Pattern Recognition · Computer Science 2023-01-24 Hosein Barzekar , Yash Patel , Ling Tong , Zeyun Yu

In recent years, advances in the development of whole-slide images have laid a foundation for the utilization of digital images in pathology. With the assistance of computer images analysis that automatically identifies tissue or cell…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Jun Wang , Qianying Liu , Haotian Xie , Zhaogang Yang , Hefeng Zhou

Current analysis of tumor proliferation, the most salient prognostic biomarker for invasive breast cancer, is limited to subjective mitosis counting by pathologists in localized regions of tissue images. This study presents the first…

Computer Vision and Pattern Recognition · Computer Science 2016-10-12 Manan Shah , Christopher Rubadue , David Suster , Dayong Wang

Lymph node metastasis (LNM) is a significant prognostic factor in patients with head and neck cancer, and the ability to predict it accurately is essential for treatment optimization. PET and CT imaging are routinely used for LNM…

Importance: Lung cancer is the leading cause of cancer mortality in the US, responsible for more deaths than breast, prostate, colon and pancreas cancer combined and it has been recently demonstrated that low-dose computed tomography (CT)…

The advancement of computer-aided detection systems had a significant impact on clinical analysis and decision-making on human disease. Lung cancer requires more attention among the numerous diseases being examined because it affects both…

Image and Video Processing · Electrical Eng. & Systems 2023-05-24 Jafar Abdollahi

Early diagnosis of lung cancer is challenging due to biological uncertainty and the limited understanding of the biological mechanisms driving nodule progression. To address this, we propose Nodule-Aligned Multimodal (Latent) Diffusion…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 James Song , Yifan Wang , Chuan Zhou , Liyue Shen

Early detection of lung cancer has been proven to decrease mortality significantly. A recent development in computed tomography (CT), spectral CT, can potentially improve diagnostic accuracy, as it yields more information per scan than…

Computer Vision and Pattern Recognition · Computer Science 2020-07-01 Linde S. Hesse , Pim A. de Jong , Josien P. W. Pluim , Veronika Cheplygina

Lung cancer is one of the major causes of death worldwide, and Vietnam is not an exception. This disease is the second most common type of cancer globally and the second most common cause of death in Vietnam, just after liver cancer, with…

Machine Learning · Computer Science 2025-04-14 Ngoc Hong Tran , Lan Kim Vien , Ngoc-Thao Thi Le

Lung cancer has the highest mortality rate of deadly cancers in the world. Early detection is essential to treatment of lung cancer. However, detection and accurate diagnosis of pulmonary nodules depend heavily on the experiences of…

Image and Video Processing · Electrical Eng. & Systems 2022-04-12 Chenglong Wang , Yun Liu , Fen Wang , Chengxiu Zhang , Yida Wang , Mei Yuan , Guang Yang