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We introduce a superstatistical model for the progression statistics of malignant cancer cells. The metastatic cascade is modeled as a complex nonequilibrium system with several macroscopic pathways and inverse-chi-square distributed…

Medical Physics · Physics 2007-11-30 L. Leon Chen , Christian Beck

Cancer stage is a large determinant of patient prognosis and management in many cancer types, and is often assessed using medical imaging modalities, such as CT and MRI. These medical images contain rich information that can be explored to…

Image and Video Processing · Electrical Eng. & Systems 2022-03-11 Jianan Chen , Anne L. Martel

According to GHO (Global Health Observatory (GHO), the high prevalence of a large variety of diseases such as Ischaemic heart disease, stroke, lung cancer disease and lower respiratory infections have remained the top killers during the…

Artificial Intelligence · Computer Science 2020-09-17 Mayssa Ben Kahla , Dalel Kanzari , Ahmed Maalel

As biomedical sciences discover new layers of complexity in the mechanisms of life and disease, mathematical models trying to catch up with these developments become mathematically intractable. As a result, in the grand scheme of things,…

Quantitative Methods · Quantitative Biology 2019-06-06 Leonid Hanin

Lung cancer is the leading cause for cancer related deaths. As such, there is an urgent need for a streamlined process that can allow radiologists to provide diagnosis with greater efficiency and accuracy. A powerful tool to do this is…

Computer Vision and Pattern Recognition · Computer Science 2017-03-29 Devinder Kumar , Mohammad Javad Shafiee , Audrey G. Chung , Farzad Khalvati , Masoom A. Haider , Alexander Wong

Brain metastases affect approximately between 20% and 40% of cancer patients and are commonly treated with radiotherapy or radiosurgery. Early prediction of recurrence following treatment could enable timely clinical intervention and…

Image and Video Processing · Electrical Eng. & Systems 2025-12-18 Ines Faria , Matheus Silva , Crystian Saraiva , Jose Soares , Victor Alves

With an estimated 160,000 deaths in 2018, lung cancer is the most common cause of cancer death in the United States. Lung cancer CT screening has been shown to reduce mortality by up to 40% and is now included in US screening guidelines.…

Image and Video Processing · Electrical Eng. & Systems 2020-07-28 Daniel Korat

Lung cancer is the leading cause of cancer-related mortality worldwide. Lung cancer screening (LCS) using annual low-dose computed tomography (CT) scanning has been proven to significantly reduce lung cancer mortality by detecting cancerous…

Metastasis represents one of the main clinical challenge in cancer treatment since it is associated with the majority of deaths. Recent technological advances allow quantification of the dynamics of the process by means of noninvasive…

Tissues and Organs · Quantitative Biology 2015-11-06 Sébastien Benzekry , J. M. L. Ebos

Collectively, lung cancer, breast cancer and melanoma was diagnosed in over 535,340 people out of which, 209,400 deaths were reported [13]. It is estimated that over 600,000 people will be diagnosed with these forms of cancer in 2015. Most…

Machine Learning · Computer Science 2015-09-29 Mohnish Chakravarti , Tanay Kothari

A recently proposed single progenitor cell model for skin cell proliferation [Clayton et al., Nature v446, 185 (2007)] is extended to incorporate homeostasis as a fixed point of the dynamics. Unlimited cell proliferation in such a model can…

Cell Behavior · Quantitative Biology 2009-03-05 Patrick B. Warren

Using fiducial markers on patient's body surface to predict the tumor location is a widely used approach in lung cancer radiotherapy. The purpose of this work is to propose an algorithm that automatically identifies a sparse set of…

Medical Physics · Physics 2015-06-04 Bin Dong , Yan Jiang Graves , Xun Jia , Steve B. Jiang

The present study shows that the performance of CNN is not significantly different from the best classical methods and human doctors for classifying mediastinal lymph node metastasis of NSCLC from PET/CT images. Because CNN does not need…

Computer Vision and Pattern Recognition · Computer Science 2017-02-09 Hongkai Wang , Zongwei Zhou , Yingci Li , Zhonghua Chen , Peiou Lu , Wenzhi Wang , Wanyu Liu , Lijuan Yu

Lung cancer (LC) remains the primary cause of cancer-related mortality, largely due to late-stage diagnoses. Effective strategies for early detection are therefore of paramount importance. In recent years, machine learning (ML) has…

The early detection and nuanced subtype classification of non-small cell lung cancer (NSCLC), a predominant cause of cancer mortality worldwide, is a critical and complex issue. In this paper, we introduce an innovative integration of…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Salma Hassan , Hamad Al Hammadi , Ibrahim Mohammed , Muhammad Haris Khan

Medical imaging is a critical initial tool used by clinicians to determine a patient's cancer diagnosis, allowing for faster intervention and more reliable patient prognosis. At subsequent stages of patient diagnosis, genetic information is…

Computer Vision and Pattern Recognition · Computer Science 2025-12-03 Rahul Mehta

Lung cancer is the leading cause of cancer death and morbidity worldwide. Many studies have shown machine learning models to be effective at detecting lung nodules from chest X-ray images. However, these techniques have yet to be embraced…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Michael J. Horry , Subrata Chakraborty , Biswajeet Pradhan , Manoranjan Paul , Douglas P. S. Gomes , Anwaar Ul-Haq

Survival prediction is a crucial task associated with cancer diagnosis and treatment planning. This paper presents a novel approach to survival prediction by harnessing comprehensive information from CT and PET scans, along with associated…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Aiman Farooq , Deepak Mishra , Santanu Chaudhury

Statistical models for predicting lung cancer have the potential to facilitate earlier diagnosis of malignancy and avoid invasive workup of benign disease. Many models have been published, but comparative studies of their utility in…

Lung cancer is the leading cause of cancer-related death worldwide, and early diagnosis is critical to improving patient outcomes. To diagnose cancer, a highly trained pulmonologist must navigate a flexible bronchoscope deep into the…

Computer Vision and Pattern Recognition · Computer Science 2019-07-19 Jake Sganga , David Eng , Chauncey Graetzel , David B. Camarillo