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During the noisy intermediate-scale quantum (NISQ) era, quantum computational approaches refined to overcome the challenge of limited quantum resources are highly valuable. However, the accuracy of the molecular properties predicted by most…

Quantum Physics · Physics 2023-12-20 Shih-Kai Chou , Jyh-Pin Chou , Alice Hu , Yuan-Chung Cheng , Hsi-Sheng Goan

Noisy quantum annealing experiments on Rydberg atom arrays produce measurement outcomes that deviate from ideal distributions, complicating performance evaluation. To enable a data-driven benchmarking methodology for quantum devices that…

Quantum Physics · Physics 2026-02-06 Juyoung Park , Junwoo Jung , Jaewook Ahn

Quantum computing not only holds the potential to solve long-standing problems in quantum physics, but also to offer speed-ups across a broad spectrum of other fields. However, due to the noise and the limited scale of current quantum…

Quantum Physics · Physics 2024-03-05 Julien Gacon

Variational algorithms are a promising paradigm for utilizing near-term quantum devices for modeling electronic states of molecular systems. However, previous bounds on the measurement time required have suggested that the application of…

In the race towards quantum computing, the potential benefits of quantum neural networks (QNNs) have become increasingly apparent. However, Noisy Intermediate-Scale Quantum (NISQ) processors are prone to errors, which poses a significant…

Artificial Intelligence · Computer Science 2023-11-27 Erik B. Terres Escudero , Danel Arias Alamo , Oier Mentxaka Gómez , Pablo García Bringas

Variational quantum algorithms provide a direct, physics-based approach to protein structure prediction, but their accuracy is limited by the coarse resolution of the energy landscapes generated on current noisy devices. We propose a hybrid…

Emerging Technologies · Computer Science 2025-10-09 Yuqi Zhang , Yuxin Yang , Feixiong Chen , Cheng-Chang Lu , Nima Saeidi , Samuel L. Volchenboum , Junhan Zhao , Siwei Chen , Weiwen Jiang , Qiang Guan

Quantum machine learning is considered one of the flagship applications of quantum computers, where variational quantum circuits could be the leading paradigm both in the near-term quantum devices and the early fault-tolerant quantum…

Quantum Physics · Physics 2024-12-17 Yuqing Li , Jinglei Cheng , Xulong Tang , Youtao Zhang , Frederic T. Chong , Junyu Liu

We present a quantum chemistry benchmark for noisy intermediate-scale quantum computers that leverages the variational quantum eigensolver, active space reduction, a reduced unitary coupled cluster ansatz, and reduced density purification…

Quantum computing has the potential to revolutionize quantum chemistry and material science by offering solutions to complex problems unattainable with classical computers. However, the development of efficient quantum algorithms that are…

The Variational Quantum Eigensolver (VQE) algorithm, as applied to finding the ground state of a Hamiltonian, is particularly well-suited for deployment on noisy intermediate-scale quantum (NISQ) devices. Here we utilize the VQE algorithm…

Quantum Physics · Physics 2024-11-28 Younes Javanmard , Ugne Liaubaite , Tobias J. Osborne , Xusheng Xu , Man-Hong Yung

Recently, tremendous progress has been made in the field of quantum science and technologies: different platforms for quantum simulation as well as quantum computing, ranging from superconducting qubits to neutral atoms, are starting to…

Hybrid quantum-classical algorithms have been proposed to circumvent noise limitations in quantum computers. Such algorithms delegate only a calculation of the expectation value to the quantum computer. Among them, the Variational Quantum…

Strongly Correlated Electrons · Physics 2022-11-02 Baptiste Anselme Martin , Pascal Simon , Marko J. Rančić

We describe a resource-efficient approach to studying many-body quantum states on noisy, intermediate-scale quantum devices. We employ a sequential generation model that allows us to bound the range of correlations in the resulting…

Quantum Physics · Physics 2021-03-05 Johannes Borregaard , Matthias Christandl , Daniel Stilck França

Quantum computational chemistry has emerged as an important application of quantum computing. Hybrid quantum-classical computing methods, such as variational quantum eigensolvers (VQE), have been designed as promising solutions to quantum…

As a hybrid quantum-classical algorithm, the variational quantum eigensolver is widely applied in quantum chemistry simulations, especially in computing the electronic structure of complex molecular systems. However, on existing noisy…

Quantum Physics · Physics 2025-01-28 Wanqi Sun , Jungang Xu , Chenghua Duan

Characterisation protocols have so far played a central role in the development of noisy intermediate-scale quantum (NISQ) computers capable of impressive quantum feats. This trajectory is expected to continue in building the next…

Quantum subspace diagonalization and quantum Krylov algorithms offer a feasible, pre- or early-fault tolerant alternative to quantum phase estimation for using quantum computers to estimate the low-lying spectra of quantum systems. However,…

Near-term quantum computers are noisy, and therefore must run algorithms with a low circuit depth and qubit count. Here we investigate how noise affects a quantum neural network (QNN) for state discrimination, applicable on near-term…

Quantum Physics · Physics 2021-01-27 Andrew Patterson , Hongxiang Chen , Leonard Wossnig , Simone Severini , Dan Browne , Ivan Rungger

Synthesizable molecular design (also known as synthesizable molecular optimization) is a fundamental problem in drug discovery, and involves designing novel molecular structures to improve their properties according to drug-relevant oracle…

Machine Learning · Computer Science 2026-05-07 Dannong Wang , Jintai Chen , Yingzhou Lu , Minjie Shen , Lulu Chen , Zhiding Liang , Tianfan Fu , Xiao-Yang Liu

Noisy-Intermediate-Scale-Quantum (NISQ) devices are nowadays starting to become available to the final user, hence potentially allowing to show the quantum speedups predicted by the quantum information theory. However, before implementing…

Quantum Physics · Physics 2023-03-02 Paolo Braccia , Leonardo Banchi , Filippo Caruso
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