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The brain can learn to solve a wide range of tasks with high temporal and energetic efficiency. However, most biological models are composed of simple single compartment neurons and cannot achieve the state-of-art performances of artificial…

Neurons and Cognition · Quantitative Biology 2026-04-13 Cristiano Capone , Cosimo Lupo , Paolo Muratore , Pier Stanislao Paolucci

Representing networks in a low dimensional latent space is a crucial task with many interesting applications in graph learning problems, such as link prediction and node classification. A widely applied network representation learning…

Machine Learning · Computer Science 2019-11-21 Abdulkadir Çelikkanat , Fragkiskos D. Malliaros

We develop an approach for Bayesian learning of spatiotemporal dynamical mechanistic models. Such learning consists of statistical emulation of the mechanistic system that can efficiently interpolate the output of the system from arbitrary…

Methodology · Statistics 2025-07-11 Sudipto Banerjee , Xiang Chen , Ian Frankenburg , Daniel Zhou

Energy-Based Models (EBMs) have proven to be a highly effective approach for modelling densities on finite-dimensional spaces. Their ability to incorporate domain-specific choices and constraints into the structure of the model through…

Machine Learning · Computer Science 2023-02-24 Jen Ning Lim , Sebastian Vollmer , Lorenz Wolf , Andrew Duncan

Stochastic discriminative EM (sdEM) is an online-EM-type algorithm for discriminative training of probabilistic generative models belonging to the exponential family. In this work, we introduce and justify this algorithm as a stochastic…

Machine Learning · Computer Science 2017-04-05 Andres R. Masegosa

Current state-of-the-art generative models map noise to data distributions by matching flows or scores. A key limitation of these models is their inability to readily integrate available partial observations and additional priors. In…

Traditional molecule generation methods often rely on sequence- or graph-based representations, which can limit their expressive power or require complex permutation-equivariant architectures. This paper introduces a novel paradigm for…

Machine Learning · Computer Science 2025-02-18 Van Khoa Nguyen , Maciej Falkiewicz , Giangiacomo Mercatali , Alexandros Kalousis

Equilibrium Propagation (EP) is a powerful and more bio-plausible alternative to conventional learning frameworks such as backpropagation. The effectiveness of EP stems from the fact that it relies only on local computations and requires…

Neural and Evolutionary Computing · Computer Science 2023-08-23 Malyaban Bal , Abhronil Sengupta

Energy-based modeling is a promising approach to unsupervised learning, which yields many downstream applications from a single model. The main difficulty in learning energy-based models with the "contrastive approaches" is the generation…

Machine Learning · Computer Science 2021-11-30 Kirill Neklyudov , Priyank Jaini , Max Welling

Sequential neuronal activity underlies a wide range of processes in the brain. Neuroscientific evidence for neuronal sequences has been reported in domains as diverse as perception, motor control, speech, spatial navigation and memory.…

Adaptation and Self-Organizing Systems · Physics 2020-04-03 Sascha Frölich , Dimitrije Marković , Stefan J. Kiebel

The recently developed variational autoencoders (VAEs) have proved to be an effective confluence of the rich representational power of neural networks with Bayesian methods. However, most work on VAEs use a rather simple prior over the…

Machine Learning · Computer Science 2017-08-29 Prasoon Goyal , Zhiting Hu , Xiaodan Liang , Chenyu Wang , Eric Xing

Imbalanced classification remains a pervasive challenge in machine learning, particularly when minority samples are too scarce to provide a robust discriminative boundary. In such extreme scenarios, conventional models often suffer from…

Machine Learning · Computer Science 2026-04-29 Hongfei Wu , Ruijian Han , Yancheng Yuan

The free energy principle (FEP) in the neurosciences stipulates that all viable agents induce and minimize informational free energy in the brain to fit their environmental niche. In this study, we continue our effort to make the FEP a more…

Neurons and Cognition · Quantitative Biology 2021-01-25 Chang Sub Kim

Energy-based models (EBMs) are flexible generative architectures inspired by statistical physics, but their learning and generative properties remain poorly understood. Here, we analyze a solvable EBM in the high-dimensional limit: the…

Machine Learning · Computer Science 2026-05-12 Thomas Tulinski , Simona Cocco , Rémi Monasson , Jorge Fernandez-De-Cossio-Diaz

Graph neural networks (GNNs), which propagate the node features through the edges and learn how to transform the aggregated features under label supervision, have achieved great success in supervised feature extraction for both node-level…

Machine Learning · Statistics 2022-11-01 Yilin He , Chaojie Wang , Hao Zhang , Bo Chen , Mingyuan Zhou

The ability to accurately model random fields plays a critical role in science and engineering for problems involving uncertain, spatially-varying quantities such as heterogeneous material properties and turbulent flows. Deep generative…

A well-known approach to describe the dynamics of an open quantum system is to compute the master equation evolving the reduced density matrix of the system. This approach plays an important role in describing excitation transfer through…

Quantum Physics · Physics 2022-10-25 Kimara Naicker , Ilya Sinayskiy , Francesco Petruccione

We consider the closely related problems of sampling from a distribution known up to a normalizing constant, and estimating said normalizing constant. We show how variational autoencoders (VAEs) can be applied to this task. In their…

Machine Learning · Computer Science 2022-09-22 George T. Cantwell

Gaussian state space models have been used for decades as generative models of sequential data. They admit an intuitive probabilistic interpretation, have a simple functional form, and enjoy widespread adoption. We introduce a unified…

Machine Learning · Statistics 2016-12-06 Rahul G. Krishnan , Uri Shalit , David Sontag

Generative models have emerged as powerful tools in medical imaging, enabling tasks such as segmentation, anomaly detection, and high-quality synthetic data generation. These models typically rely on learning meaningful latent…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Jordi Malé , Juan Fortea , Mateus Rozalem-Aranha , Neus Martínez-Abadías , Xavier Sevillano
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