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Artificial Intelligence (AI) is rapidly embedded in critical decision-making systems, however their foundational ``black-box'' models require eXplainable AI (XAI) solutions to enhance transparency, which are mostly oriented to experts,…

Machine Learning · Computer Science 2025-06-17 Eva Paraschou , Ioannis Arapakis , Sofia Yfantidou , Sebastian Macaluso , Athena Vakali

Super-resolution microscopy, or nanoscopy, enables the use of fluorescent-based molecular localization tools to study molecular structure at the nanoscale level in the intact cell, bridging the mesoscale gap to classical structural biology…

Subcellular Processes · Quantitative Biology 2024-05-28 Ivan R. Nabi , Ben Cardoen , Ismail M. Khater , Guang Gao , Timothy H. Wong , Ghassan Hamarneh

Trust and interpretability are crucial for the use of Artificial Intelligence (AI) in scientific research, but current models often operate as black boxes offering limited transparency and justifications for their outputs. We introduce…

Optical multilayer thin-films are fundamental components that enable the precise control of reflectance, transmittance, and phase shift in the design of photonic systems. Rapid and accessible simulation of these structures holds critical…

Computational Physics · Physics 2025-10-27 Bahrem Serhat Danis , Esra Zayim

Deep learning (DL) has revolutionized the field of document image analysis, showcasing superhuman performance across a diverse set of tasks. However, the inherent black-box nature of deep learning models still presents a significant…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Saifullah Saifullah , Stefan Agne , Andreas Dengel , Sheraz Ahmed

Computational workflows are a common class of application on supercomputers, yet the loosely coupled and heterogeneous nature of workflows often fails to take full advantage of their capabilities. We created Colmena to leverage the massive…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-08-27 Logan Ward , J. Gregory Pauloski , Valerie Hayot-Sasson , Yadu Babuji , Alexander Brace , Ryan Chard , Kyle Chard , Rajeev Thakur , Ian Foster

As machine learning models become increasingly prevalent in medical diagnostics, the need for interpretability and transparency becomes paramount. The XAI Renaissance signifies a significant shift in the field, aiming to redefine the…

Machine Learning · Computer Science 2023-06-05 Sujith K Mandala

Explainable artificial intelligence (XAI) is one of the most intensively developed area of AI in recent years. It is also one of the most fragmented with multiple methods that focus on different aspects of explanations. This makes difficult…

Artificial Intelligence · Computer Science 2024-09-10 Szymon Bobek , Grzegorz J. Nalepa

The past decade has seen significant progress in artificial intelligence (AI), which has resulted in algorithms being adopted for resolving a variety of problems. However, this success has been met by increasing model complexity and…

Machine Learning · Computer Science 2021-11-15 Waddah Saeed , Christian Omlin

Explainable AI (XAI) has been proposed as a valuable tool to assist in downstream tasks involving human and AI collaboration. Perhaps the most psychologically valid XAI techniques are case based approaches which display 'whole' exemplars to…

Artificial Intelligence · Computer Science 2023-11-07 Eoin Kenny , Eoin Delaney , Mark Keane

As the manufacturing industry advances with sensor integration and automation, the opaque nature of deep learning models in machine learning poses a significant challenge for fault detection and diagnosis. And despite the related predictive…

Artificial Intelligence · Computer Science 2024-06-11 Ahmed Maged , Salah Haridy , Herman Shen

Artificial Intelligence (AI) has continued to achieve tremendous success in recent times. However, the decision logic of these frameworks is often not transparent, making it difficult for stakeholders to understand, interpret or explain…

Machine Learning · Computer Science 2025-01-20 Fuseini Mumuni , Alhassan Mumuni

Super-resolution imaging has revolutionized the study of systems ranging from molecular structures to distant galaxies. However, existing super-resolution methods require extensive calibration and retraining for each imaging setup, limiting…

Optics · Physics 2026-03-24 Dominik Vašinka , Filip Juráň , Jaromír Běhal , Miroslav Ježek

Explainable Artificial Intelligence (XAI) is a rising field in AI. It aims to produce a demonstrative factor of trust, which for human subjects is achieved through communicative means, which Machine Learning (ML) algorithms cannot solely…

Machine Learning · Computer Science 2021-03-09 Jamie Andrew Duell

We describe and demonstrate an optimization-based x-ray image reconstruction framework called Adorym. Our framework provides a generic forward model, allowing one code framework to be used for a wide range of imaging methods ranging from…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 Ming Du , Saugat Kandel , Junjing Deng , Xiaojing Huang , Arnaud Demortiere , Tuan Tu Nguyen , Remi Tucoulou , Vincent De Andrade , Qiaoling Jin , Chris Jacobsen

The design of astronomical hardware operating at the diffraction limit requires optimisation of physical optical simulations of the instrument with respect to desired figures of merit, such as photometric or astrometric precision. System…

Instrumentation and Methods for Astrophysics · Physics 2026-04-02 Louis Desdoigts , Benjamin Pope , Michael Gully-Santiago , Peter Tuthill

The recent Artificial Intelligence (AI) revolution has opened transformative possibilities for the humanities, particularly in unlocking the visual-artistic content embedded in historical illuminated manuscripts. While digital archives now…

Information Retrieval · Computer Science 2026-01-13 Yoav Evron , Michal Bar-Asher Siegal , Michael Fire

We present jax-cosmo, a library for automatically differentiable cosmological theory calculations. It uses the JAX library, which has created a new coding ecosystem, especially in probabilistic programming. As well as batch acceleration,…

Cosmology and Nongalactic Astrophysics · Physics 2023-05-01 Jean-Eric Campagne , François Lanusse , Joe Zuntz , Alexandre Boucaud , Santiago Casas , Minas Karamanis , David Kirkby , Denise Lanzieri , Yin Li , Austin Peel

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

Scientific discovery increasingly entails long-horizon exploration of complex hypothesis spaces, yet most existing approaches emphasize final performance while offering limited insight into how scientific exploration unfolds over time,…