Related papers: Discontinuous Galerkin approximations of the heter…
Neurocognitive disorders, such as Alzheimer's and Parkinson's, have a wide social impact. These proteinopathies involve misfolded proteins accumulating into neurotoxic aggregates. Mathematical and computational models describing the…
Many neurodegenerative diseases are connected to the spreading of misfolded prionic proteins. In this paper, we analyse the process of misfolding and spreading of both $\alpha$-synuclein and Amyloid-$\beta$, related to Parkinson's and…
This spreading of prion proteins is at the basis of brain neurodegeneration. This paper deals with the numerical modelling of the misfolding process of $\alpha$-synuclein in Parkinson's disease. We introduce and analyze a discontinuous…
The spreading of misfolded proteins is a known hallmark in some neurodegenerative diseases, known as proteinopathies. A significant example is the tau protein, associated with many pathologies, such as Alzheimer's. In this work, we discuss…
Epilepsy is a clinical neurological disorder characterized by recurrent and spontaneous seizures consisting of abnormal high-frequency electrical activity in the brain. In this condition, the transmembrane potential dynamics are…
We present and analyze a high-order discontinuous Galerkin method for the space discretization of the wave propagation model in thermo-poroelastic media. The proposed scheme supports general polytopal grids. Stability analysis and…
We study the numerical approximation of a coupled hyperbolic-parabolic system by a family of discontinuous Galerkin space-time finite element methods. The model is rewritten as a first-order evolutionary problem that is treated by the…
We present and analyze a discontinuous Galerkin method for the numerical modelling of the non-linear fully-coupled thermo-poroelastic problem. For the spatial discretization, we design a high-order discontinuous Galerkin method on polygonal…
This work presents a structure-preserving, high-order, unconditionally stable numerical method for approximating the solution to the Fisher-Kolmogorov equation on polytopic meshes, with a particular focus on its application in simulating…
We propose an $hp$-adaptive discontinuous Galerkin finite element method (DGFEM) to approximate the solution of a static crack boundary value problem. The mathematical model describes the behavior of a geometrically linear strain-limiting…
We introduce and analyze a discontinuous Galerkin method for the numerical modelling of the equations of Multiple-Network Poroelastic Theory (MPET) in the dynamic formulation. The MPET model can comprehensively describe functional changes…
This article presents a unified mathematical framework for modeling coupled poro-viscoelastic and thermo-viscoelastic phenomena, formulated as a system of first-order in time partial differential equations. The model describes the evolution…
We study the numerical approximation by space-time finite element methods of a multi-physics system coupling hyperbolic elastodynamics with parabolic transport and modeling poro- and thermoelasticity. The equations are rewritten as a…
The aim of this work is to introduce and analyze a finite element discontinuous Galerkin method on polygonal meshes for the numerical discretization of acoustic waves propagation through poroelastic materials. Wave propagation is modeled by…
This paper proposes semi-discrete and fully discrete hybridizable discontinuous Galerkin (HDG) methods for the Burgers' equation in two and three dimensions. In the spatial discretization, we use piecewise polynomials of degrees $ k \ (k…
The aim of this paper is to apply a high-order discontinuous-in-time scheme to second-order hyperbolic partial differential equations (PDEs). We first discretize the PDEs in time while keeping the spatial differential operators…
The aim of this paper is to introduce, analyse and test in practice a new mathematical model describing the interplay between biological tissue atrophy driven by pathogen diffusion, with applications to neurodegenerative disorders. This…
This work aims at presenting a Discontinuous Galerkin (DG) formulation employing a spectral basis for two important models employed in cardiac electrophysiology, namely the monodomain and bidomain models. The use of DG methods is motivated…
This work is concerned with the analysis of a space-time finite element discontinuous Galerkin method on polytopal meshes (XT-PolydG) for the numerical discretization of wave propagation in coupled poroelastic-elastic media. The…
We propose and analyze a hybridized discontinuous Galerkin (HDG) method for the spherically symmetric Einstein--scalar system in Bondi gauge. After rewriting the model as a local first-order PDE--ODE system by introducing suitable scaled…