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Ultrasound localization microscopy has enabled super-resolution vascular imaging through precise localization of individual ultrasound contrast agents (microbubbles) across numerous imaging frames. However, analysis of high-density regions…
Recently, super-resolution ultrasound imaging with ultrasound localization microscopy (ULM) has received much attention. However, ULM relies on low concentrations of microbubbles in the blood vessels, ultimately resulting in long…
Ultrasound Localization Microscopy (ULM) can map microvessels at a resolution of a few micrometers (\mu m). Transcranial ULM remains challenging in presence of aberrations caused by the skull, which lead to localization errors. Herein, we…
Resolving arterial flows is essential for understanding cardiovascular pathologies, improving diagnosis, and monitoring patient condition. Ultrasound contrast imaging uses microbubbles to enhance the scattering of the blood pool, allowing…
Ultrasound Localization Microscopy (ULM) is a non-invasive technique that allows for the imaging of micro-vessels in vivo, at depth and with a resolution on the order of ten microns. ULM is based on the sub-resolution localization of…
Ultrasound Localization Microscopy (ULM) has recently enabled the mapping of the cerebral vasculature in vivo with a resolution ten times smaller than the wavelength used, down to ten microns. However, with frame rates up to 20.000 frames…
Transcranial ultrasound imaging is usually limited by skull-induced attenuation and high-order aberrations. By using contrast agents such as microbubbles in combination with ultrafast imaging, not only can the signal-to-noise ratio be…
Ultrasound Localization Microscopy (ULM) offers a cost-effective modality for microvascular imaging by using intravascular contrast agents (microbubbles). However, ULM has a fundamental trade-off between acquisition time and spatial…
Object segmentation and structure localization are important steps in automated image analysis pipelines for microscopy images. We present a convolution neural network (CNN) based deep learning architecture for segmentation of objects in…
Ultrasound localization microscopy offers new radiation-free diagnostic tools for vascular imaging deep within the tissue. Sequential localization of echoes returned from inert microbubbles with low-concentration within the bloodstream…
The purpose of this study is to enable in-vivo three-dimensional (3-D) ultrasound localization microscopy (ULM) of posterior ocular microvasculature using a 256-channel system and a 1024-element matrix array, and to overcome limitations of…
Mapping blood microflows of the whole brain is crucial for early diagnosis of cerebral diseases. Ultrasound localization microscopy (ULM) was recently applied to map and quantify blood microflows in 2D in the brain of adult patients down to…
Super-resolution ultrasound (SR-US) is a powerful imaging technique for capturing microvasculature and blood flow at high spatial resolution. However, accurate microbubble (MB) localization remains a key challenge, as errors in localization…
Super-resolution ultrasound imaging through microbubble (MB) localisation and tracking, also known as ultrasound localisation microscopy, allows non-invasive sub-diffraction resolution imaging of microvasculature in animals and humans. The…
Super-resolution ultrasound imaging relies on the sub-wavelength localization of microbubble contrast agents. By tracking individual microbubbles, the velocity and flow within microvessels can be estimated. However, a 2D super-resolution…
Ultrasound localization microscopy (ULM) enables microvascular imaging at spatial resolutions beyond the acoustic diffraction limit, offering significant clinical potentials. However, ULM performance relies heavily on microbubble (MB)…
Ultrasound localization microscopy (ULM) refers to a promising medical imaging modality that systematically leverages the advantages of contrast-enhanced ultrasound (CEUS) to surpass the diffraction barrier and delineate the microvascular…
Health professionals extensively use Two- Dimensional (2D) Ultrasound (US) videos and images to visualize and measure internal organs for various purposes including evaluation of muscle architectural changes. US images can be used to…
Deep learning methods can be found in many medical imaging applications. Recently, those methods were applied directly to the RF ultrasound multi-channel data to enhance the quality of the reconstructed images. In this paper, we apply a…
One primary technical challenge in photoacoustic microscopy (PAM) is the necessary compromise between spatial resolution and imaging speed. In this study, we propose a novel application of deep learning principles to reconstruct…