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Datasets from single-molecule experiments often reflect a large variety of molecular behaviour. The exploration of such datasets can be challenging, especially if knowledge about the data is limited and a priori assumptions about expected…

Data Analysis, Statistics and Probability · Physics 2020-04-06 Anton Vladyka , Tim Albrecht

We present a methodology for using unlabeled data to design semi-supervised learning (SSL) methods that improve the predictive performance of supervised learning for regression tasks. The main idea is to design different mechanisms for…

Methodology · Statistics 2025-11-18 Oren Yuval , Saharon Rosset

Missing value imputation is an important practical problem. There is a large body of work on it, but there does not exist any work that formulates the problem in a structured output setting. Also, most applications have constraints on the…

Machine Learning · Computer Science 2013-11-12 Rahul Kidambi , Vinod Nair , Sundararajan Sellamanickam , S. Sathiya Keerthi

Missing data is a pervasive problem in epidemiology, with multiple imputation (MI) a commonly used analysis method. MI is valid when data are missing at random (MAR). However, definitions of MAR with multiple incomplete variables are not…

Methodology · Statistics 2025-04-14 Paul Madley-Dowd , Rachael A. Hughes , Maya B. Mathur , Jon Heron , Kate Tilling

Missing data are ubiquitous in real world applications and, if not adequately handled, may lead to the loss of information and biased findings in downstream analysis. Particularly, high-dimensional incomplete data with a moderate sample…

Machine Learning · Computer Science 2022-12-23 Zongyu Dai , Zhiqi Bu , Qi Long

Missing data present challenges in data analysis. Naive analyses such as complete-case and available-case analysis may introduce bias and loss of efficiency, and produce unreliable results. Multiple imputation (MI) is one of the most widely…

Methodology · Statistics 2019-05-15 Domonique W. Hodge , Sandra E. Safo , Qi Long

Balancing the distributions of the confounders across the exposure levels in an observational study through matching or weighting is an accepted method to control for confounding due to these variables when estimating the association…

Methodology · Statistics 2021-08-24 Farhad Pishgar , Noah Greifer , Clémence Leyrat , Elizabeth Stuart

Diabetes is a serious chronic metabolic disease. In the recent years, more and more consumer technology enterprises focusing on human health are committed to implementing accurate and non-invasive blood glucose algorithm in their products.…

Machine Learning · Computer Science 2025-03-05 Yiting Wei , Bingo Wing-Kuen Ling , Qing Liu , Jiaxin Liu

Data from discovery proteomic and phosphoproteomic experiments typically include missing values that correspond to proteins that have not been identified in the analyzed sample. Replacing the missing values with random numbers, a process…

Quantitative Methods · Quantitative Biology 2019-10-01 Matus Medo , Daniel M. Aebersold , Michaela Medova

In the last couple of decades, there has been major advancements in the domain of missing data imputation. The techniques in the domain include amongst others: Expectation Maximization, Neural Networks with Evolutionary Algorithms or…

Neural and Evolutionary Computing · Computer Science 2015-12-07 Collins Leke , Tshilidzi Marwala , Satyakama Paul

As the availability of omics data has increased in the last few years, more multi-omics data have been generated, that is, high-dimensional molecular data consisting of several types such as genomic, transcriptomic, or proteomic data, all…

Genomics · Quantitative Biology 2023-02-09 Roman Hornung , Frederik Ludwigs , Jonas Hagenberg , Anne-Laure Boulesteix

The integration of DNA methylation data with a Whole Slide Image (WSI) offers significant potential for enhancing the diagnostic precision of central nervous system (CNS) tumor classification in neuropathology. While existing approaches…

Computer Vision and Pattern Recognition · Computer Science 2024-12-12 Omnia Alwazzan , Amaya Gallagher-Syed , Thomas O. Millner , Sebastian Brandner , Ioannis Patras , Silvia Marino , Gregory Slabaugh

Missing data can pose a challenge for machine learning (ML) modeling. To address this, current approaches are categorized into feature imputation and label prediction and are primarily focused on handling missing data to enhance ML…

Machine Learning · Computer Science 2023-09-19 Laixin Xie , Yang Ouyang , Longfei Chen , Ziming Wu , Quan Li

Missing values are largely inevitable in gene expression microarray studies. Data sets often have significant omissions due to individuals dropping out of experiments, errors in data collection, image corruptions, and so on. Missing data…

Quantitative Methods · Quantitative Biology 2018-09-18 Marie Li

In the integrative analyses of omics data, it is often of interest to extract data representation from one data type that best reflect its relations with another data type. This task is traditionally fulfilled by linear methods such as…

Applications · Statistics 2021-03-30 Tianwei Yu

Time series classification with missing data is a prevalent issue in time series analysis, as temporal data often contain missing values in practical applications. The traditional two-stage approach, which handles imputation and…

Machine Learning · Computer Science 2024-08-13 Pengshuai Yao , Mengna Liu , Xu Cheng , Fan Shi , Huan Li , Xiufeng Liu , Shengyong Chen

Missing values, widely called as \textit{sparsity} in literature, is a common characteristic of many real-world datasets. Many imputation methods have been proposed to address this problem of data incompleteness or sparsity. However, the…

Machine Learning · Computer Science 2022-07-28 Vishwas Choudhary , Binay Gupta , Anirban Chatterjee , Subhadip Paul , Kunal Banerjee , Vijay Agneeswaran

Multimodal approaches that integrate histology and genomics hold strong potential for precision oncology. However, phenotypic and genotypic heterogeneity limits the quality of intra-modal representations and hinders effective inter-modal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Yupei Zhang , Yating Huang , Wanming Hu , Lequan Yu , Hujun Yin , Chao Li

Graph neural networks (GNNs) are popular weapons for modeling relational data. Existing GNNs are not specified for attribute-incomplete graphs, making missing attribute imputation a burning issue. Until recently, many works notice that GNNs…

Machine Learning · Computer Science 2022-12-01 Ziqi Gao , Yifan Niu , Jiashun Cheng , Jianheng Tang , Tingyang Xu , Peilin Zhao , Lanqing Li , Fugee Tsung , Jia Li

Often in real-world datasets, especially in high dimensional data, some feature values are missing. Since most data analysis and statistical methods do not handle gracefully missing values, the first step in the analysis requires the…

Machine Learning · Statistics 2016-12-08 Yehezkel S. Resheff , Daphna Weinshall