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In the genome biology research, regulatory genome modeling is an important topic for many regulatory downstream tasks, such as promoter classification, transaction factor binding sites prediction. The core problem is to model how regulatory…

Genomics · Quantitative Biology 2021-11-04 Shentong Mo , Xi Fu , Chenyang Hong , Yizhen Chen , Yuxuan Zheng , Xiangru Tang , Zhiqiang Shen , Eric P Xing , Yanyan Lan

Using language models (LMs) pre-trained in a self-supervised setting on large corpora and then fine-tuning for a downstream task has helped to deal with the problem of limited label data for supervised learning tasks such as Named Entity…

Computation and Language · Computer Science 2023-08-21 Pavlova Vera , Mohammed Makhlouf

Pre-trained language models have recently contributed to significant advances in NLP tasks. Recently, multi-modal versions of BERT have been developed, using heavy pre-training relying on vast corpora of aligned textual and image data,…

Computation and Language · Computer Science 2020-12-17 Thomas Scialom , Patrick Bordes , Paul-Alexis Dray , Jacopo Staiano , Patrick Gallinari

Language model pretraining has led to significant performance gains but careful comparison between different approaches is challenging. Training is computationally expensive, often done on private datasets of different sizes, and, as we…

Computation and Language · Computer Science 2019-07-29 Yinhan Liu , Myle Ott , Naman Goyal , Jingfei Du , Mandar Joshi , Danqi Chen , Omer Levy , Mike Lewis , Luke Zettlemoyer , Veselin Stoyanov

As Large Language Models (LLMs) achieve remarkable empirical success through scaling model and data size, pretraining has become increasingly critical yet computationally prohibitive, hindering rapid development. Despite the availability of…

Computation and Language · Computer Science 2026-02-06 Ji Zhao , Yufei Gu , Shitong Shao , Xun Zhou , Liang Xiang , Zeke Xie

Bridging the exponentially growing gap between the numbers of unlabeled and labeled protein sequences, several studies adopted semi-supervised learning for protein sequence modeling. In these studies, models were pre-trained with a…

Biomolecules · Quantitative Biology 2021-09-20 Seonwoo Min , Seunghyun Park , Siwon Kim , Hyun-Soo Choi , Byunghan Lee , Sungroh Yoon

Semantic networks, such as the knowledge graph, can represent the knowledge leveraging the graph structure. Although the knowledge graph shows promising values in natural language processing, it suffers from incompleteness. This paper…

Computation and Language · Computer Science 2022-04-29 Da Li , Sen Yang , Kele Xu , Ming Yi , Yukai He , Huaimin Wang

Pre-trained Language Models (PLMs) have achieved great success on Machine Reading Comprehension (MRC) over the past few years. Although the general language representation learned from large-scale corpora does benefit MRC, the poor support…

Computation and Language · Computer Science 2021-05-19 Fangkai Jiao , Yangyang Guo , Yilin Niu , Feng Ji , Feng-Lin Li , Liqiang Nie

Over recent years, an increasing amount of compute and data has been poured into training large language models (LLMs), usually by doing one-pass learning on as many tokens as possible randomly selected from large-scale web corpora. While…

Computation and Language · Computer Science 2023-08-24 Kushal Tirumala , Daniel Simig , Armen Aghajanyan , Ari S. Morcos

Large pre-trained models have been vital in recent advancements in domains like language and vision, making model training for individual downstream tasks more efficient and provide superior performance. However, tackling time-series…

Machine Learning · Computer Science 2024-12-06 Harshavardhan Kamarthi , B. Aditya Prakash

Massively multilingual language models such as multilingual BERT offer state-of-the-art cross-lingual transfer performance on a range of NLP tasks. However, due to limited capacity and large differences in pretraining data sizes, there is a…

Computation and Language · Computer Science 2021-09-13 Jonas Pfeiffer , Ivan Vulić , Iryna Gurevych , Sebastian Ruder

Fine-tuning pre-trained models provides significant advantages in downstream performance. The ubiquitous nature of pre-trained models such as BERT and its derivatives in natural language processing has also led to a proliferation of…

Computation and Language · Computer Science 2024-05-06 Thennal D K , Ganesh Nathan , Suchithra M S

The pre-trained foundation models (PFMs) have become essential for facilitating large-scale multimodal learning. Researchers have effectively employed the ``pre-train, prompt, and predict'' paradigm through prompt learning to induce…

Computation and Language · Computer Science 2025-12-24 Xiang Chen , Yixin Ou , Quan Feng , Lei Li , Piji Li , Haibo Ye , Sheng-Jun Huang , Shuofei Qiao , Shumin Deng , Huajun Chen , Ningyu Zhang

For most natural language processing tasks, the dominant practice is to finetune large pretrained transformer models (e.g., BERT) using smaller downstream datasets. Despite the success of this approach, it remains unclear to what extent…

Computation and Language · Computer Science 2023-05-29 Kundan Krishna , Saurabh Garg , Jeffrey P. Bigham , Zachary C. Lipton

Background: Identifying relationships between clinical events and temporal expressions is a key challenge in meaningfully analyzing clinical text for use in advanced AI applications. While previous studies exist, the state-of-the-art…

Computation and Language · Computer Science 2020-04-15 Hong Guan , Jianfu Li , Hua Xu , Murthy Devarakonda

Artificial intelligence and machine learning have shown great promise in their ability to accelerate novel materials discovery. As researchers and domain scientists seek to unify and consolidate chemical knowledge, the case for models with…

Prompt learning has achieved great success in efficiently exploiting large-scale pre-trained models in natural language processing (NLP). It reformulates the downstream tasks as the generative pre-training ones to achieve consistency, thus…

Computer Vision and Pattern Recognition · Computer Science 2023-12-18 Ning Liao , Bowen Shi , Xiaopeng Zhang , Min Cao , Junchi Yan , Qi Tian

Recurrent neural networks with differentiable attention mechanisms have had success in generative and classification tasks. We show that the classification performance of such models can be enhanced by guiding a randomly initialized model…

Machine Learning · Computer Science 2017-12-18 Jack Lindsey

Every data selection method inherently has a target. In practice, these targets often emerge implicitly through benchmark-driven iteration: researchers develop selection strategies, train models, measure benchmark performance, then refine…

Many modern sequential recommender systems use deep neural networks, which can effectively estimate the relevance of items but require a lot of time to train. Slow training increases expenses, hinders product development timescales and…

Information Retrieval · Computer Science 2022-07-18 Aleksandr Petrov , Craig Macdonald
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