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Related papers: Exploring the Influence of Parametrized Pulsatilit…

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Image-based computational fluid dynamics (CFD) has emerged as a powerful tool to study cardiovascular flows while 2D echocardiography (echo) is the most widely used non-invasive imaging modality for diagnosis of heart disease. Here, echo is…

Computer vision methods typically optimize for first-order dynamics (e.g., optical flow). However, in many cases the properties of interest are subtle variations in higher-order changes, such as acceleration. This is true in the cardiac…

Image and Video Processing · Electrical Eng. & Systems 2022-03-29 Brian L. Hill , Xin Liu , Daniel McDuff

Three-dimensional cardiovascular fluid dynamics simulations typically require computation of several cardiac cycles before they reach a periodic solution, rendering them computationally expensive. Furthermore, there is currently no…

Computational Engineering, Finance, and Science · Computer Science 2021-06-28 Martin R. Pfaller , Jonathan Pham , Nathan M. Wilson , David W. Parker , Alison L. Marsden

Unnatural dynamics of the notorious vortex in the left ventricle is often associated with cardiac disease. Understanding how different cardiac diseases alter the flow physics in the left ventricle may therefore provide a powerful tool for…

Medical Physics · Physics 2019-03-18 Giuseppe Di Labbio , Lyes Kadem

Cardiopulmonary resuscitation (CPR) is one of the essential tools to ensure oxygen supply during cardiac arrest. However, the precise effects of chest compression are not quantifiable to this day. This often results in a low quality of…

Directional fluid flow in perivascular spaces surrounding cerebral arteries is hypothesized to play a key role in brain solute transport and clearance. While various drivers for pulsatile flow, such as cardiac or respiratory pulsations, are…

Fluid Dynamics · Physics 2023-10-05 Ingeborg G. Gjerde , Marie E. Rognes , Antonio L. Sanchez

Continuously measured arterial blood velocity can provide insight into physiological parameters and potential disease states. The efficient and effective description of the temporal profiles of arterial velocity is crucial for both clinical…

Quantitative Methods · Quantitative Biology 2024-02-16 Justen R Geddes , Amanda Randles

Left ventricular assist devices (LVADs) are mechanical pumps, which can be used to support heart failure (HF) patients as bridge to transplant and destination therapy. To automatically adjust the LVAD speed, a physiological control system…

Systems and Control · Electrical Eng. & Systems 2021-05-04 Masoud Fetanat , Michael Stevens , Christopher Hayward , Nigel H. Lovell

Although atrial fibrillation (AF), a common arrhythmia, frequently presents in patients with underlying valvular disease, its hemodynamic contributions are not fully understood. The present work aimed to computationally study how physical…

Understanding the formation, propagation, and breakdown of the main vortex ring (VR) is essential for characterizing left ventricular (LV) hemodynamics, as its dynamics have been linked to the onset and progression of cardiovascular…

Fluid Dynamics · Physics 2025-07-30 Eneko Lazpita , Michael Neidlin , Jesus Garicano-Mena , Soledad Le Clainche

Percutaneous catheter pumps are intraventricular temporary mechanical circulatory support (MCS) devices that are positioned across the aortic valve into the left ventricle (LV) and provide continuous antegrade blood flow from the LV into…

Medical Physics · Physics 2023-12-11 Greg W. Burgreen , Mansur Zhussupbekov , Rodrigo Méndez Rojano , James F. Antaki

Advances in computational science offer a principled pipeline for predictive modeling of cardiovascular flows and aspire to provide a valuable tool for monitoring, diagnostics and surgical planning. Such models can be nowadays deployed on…

Machine Learning · Computer Science 2019-09-19 Georgios Kissas , Yibo Yang , Eileen Hwuang , Walter R. Witschey , John A. Detre , Paris Perdikaris

Methods: A method of the pulsation for a pVAD is proposed (AP-pVAD Model). AP-pVAD Model consists of two parts: NPQ Model and LSTM-Transformer Model. (1)The NPQ Model determines the mathematical relationship between motor speed, pressure,…

Medical Physics · Physics 2025-03-11 Chaoran E , Chenghan Chen , Yuyang Shi , Haiyun Wang , Peixin Hua , Xiwen Zhang

Understanding the interaction between the valves and walls of the heart is important in assessing and subsequently treating heart dysfunction. With advancements in cardiac imaging, nonlinear mechanics and computational techniques, it is now…

Medical Physics · Physics 2017-04-07 Hao Gao , Liuyang Feng , Nan Qi , Colin Berry , Boyce Griffith , Xiaoyu Luo

Usually, clinicians assess the correct hemodynamic behavior and fetal well-being during the gestational age thanks to their professional expertise, with the support of some indices defined for Doppler fetal waveforms. Although this approach…

The impact of increased stiffness and pulsatile load on the circulation and their influence on heart performance have been documented not only for cardiovascular events but also for ventricular dysfunctions. For this reason, computer models…

Numerical Analysis · Mathematics 2021-11-11 Federica Caforio , Christoph M. Augustin , Jordi Alastruey , Matthias A. F. Gsell , Gernot Plank

A minimal model for mechanical motion of the left ventricle is proposed. The model assumes the left ventricle to be a harmonic oscillator with two distinct phases, simulating the systolic and diastolic phases, at which both the amplitude…

Medical Physics · Physics 2007-05-23 S. Dubi , C. Dubi , Y. Dubi

Computational fluid dynamics (CFD) models of blood flow in the left ventricle (LV) and aorta are important tools for analyzing the mechanistic links between myocardial deformation and flow patterns. Typically, the use of image-based…

There are more than 300,000 heart valves implanted annually worldwide with about 50% of them being mechanical valves. The heart valve replacement is often a common treatment for severe valvular disease. However, valves may dysfunction…

Fluid Dynamics · Physics 2018-03-12 Fardin Khalili , Peshala T. Gamage , Hansen Mansy

Valvular heart diseases are growing concern in impoverished parts of the world, such as Southern-Africa, claiming more than 31 % of total deaths related to cardiovascular diseases. The ability to model the effects of regurgitant and…

Medical Physics · Physics 2022-04-11 Ryno Laubscher , Jacques Liebenberg , Philip Herbst